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Protein Evolution - Laszlo Patthy - Bog - John Wiley and Sons Ltd - Plusbog.dk

This book provides an up-to-date summary of the principles of protein evolution and discusses both the methods available to analyze the evolutionary history of proteins as well as those for predicting their structure-function relationships.

DKK 759.00

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Proteomics for Biological Discovery - - Bog - John Wiley and Sons Ltd - Plusbog.dk

An update to the popular guide to proteomics technology applications in biomedical research Building on the strength of the original edition, this book presents the state of the art in the field of proteomics and offers students and scientists new tools and techniques to advance their own research. Written by leading experts in the field, it provides readers with an understanding of new and emerging directions for proteomics research and applications. Proteomics for Biological Discovery begins by discussing the emergence of proteomics technologies and summarizing the potential insights to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are thoroughly covered, from underlying concepts to limitations and future directions. Later chapters provide an overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, applied proteomics, and bioinformatics relevant to proteomics. Chapters cover: Quantitative Proteomics for Differential Protein Expression Profiling; Protein Microarrays; Protein Biomarker Discovery; Biomarker Discovery using Mass Spectrometry Imaging; Protein-Protein Interactions; Mass Spectrometry Of Intact Protein Complexes; Crosslinking Applications in Structural Proteomics; Functional Proteomics; High Resolution Interrogation of Biological Systems via Mass Cytometry; Characterization of Drug-Protein Interactions by Chemoproteomics; Phosphorylation; Large-Scale Phosphoproteomics; and Probing Glycoforms of Individual Proteins Using Antibody-Lectin Sandwich Arrays. Presents a comprehensive and coherent review of the major issues in proteomic technology development, bioinformatics, strategic approaches, and applicationsChapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applicationsFeatures new coverage of mass spectrometry for high throughput proteomic measurements, and novel quantitation strategies such as spectral counting and stable isotope labelingDiscusses higher level integrative aspects, including technical challenges and applications for drug discoveryOffers new chapters on biomarker discovery, global phosphorylation analysis, proteomic profiling using antibodies, and single cell mass spectrometry Proteomics for Biological Discovery is an excellent advanced resource for graduate students, postdoctoral fellows, and scientists across all the major fields of biomedical science.

DKK 1007.00

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Cannabinoids - Vincenzo Di Marzo - Bog - John Wiley and Sons Ltd - Plusbog.dk

Cannabinoids is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors protein molecules on the surface of cells known as cannabinoid receptors.

DKK 992.00

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Proteins - Gary Walsh - Bog - John Wiley and Sons Ltd - Plusbog.dk

Proteins Biochemistry and Biotechnology 2e is a definitive source of information for all those interested in protein science, and particularly the commercial production and isolation of specific proteins, and their subsequent utilization for applied purposes in industry and medicine.

DKK 520.00

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Glycobiology of the Immune Response, Volume 1253 - - Bog - John Wiley and Sons Ltd - Plusbog.dk

Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein-binding partners (lectins) play central roles in all innate and adaptive immune responses.

DKK 379.00

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Annals Meeting Reports - G Protein-Coupled Receptors, Complex Drugs and Regulatory Guidance, Fetal Programming and Environmental Exposures, Volume

This Annals volume presents three scholarly meeting reports: (1) biomarkers in nutrition: new frontiers in research and application; (2) the new revolution in toxicology: The good, the bad, and the ugly; and (3) neuroprotection after cerebral ischemia.

DKK 617.00

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Cell Biology - Sr Bolsover - Bog - John Wiley and Sons Ltd - Plusbog.dk

An accessible and straightforward intro to cell biology In the newly revised Fourth Edition of Cell Biology: A Short Course, a distinguished team of researchers delivers a concise and accessible introduction to modern cell biology, integrating knowledge from genetics, molecular biology, biochemistry, physiology, and microscopy. The book places a strong emphasis on drawing connections between basic science and medicine. Telling the story of cells as the units of life in a colorful and student-friendly manner, Cell Biology: A Short Course takes an “essentials only” approach. It conveys critical points without overburdening the reader with extraneous or secondary information. Clear diagrams and examples from current research accompany special boxed sections that focus on the importance of cell biology in medicine and industry. A new feature, “BrainBoxes” describes some of the key people who created the current understanding of Cell Biology. The book has been thoroughly revised and updated since the last edition and includes: Thorough introduction to cells and tissues, membranes, organelles, and the structure of DNA and genetic codeExplorations of DNA as a data storage medium, transcription and the control of gene expression, and recombinant DNA and genetic engineeringDiscussion of the manufacture of proteins, protein structure, and intracellular protein traffickingDescription of ions and voltages, intracellular and extracellular signalingIntroduction to the cytoskeleton and cell movementDiscussion of cell division and apoptosis Perfect for undergraduate students seeking an accessible, one-stop reference on cell biology, Cell Biology: A Short Course is also an ideal reference for pre-med students.

DKK 717.00

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Nutrition and Stroke - Salah Gariballa - Bog - John Wiley and Sons Ltd - Plusbog.dk

Stroke is a common and devasting event, which often results in death or major loss of independence, with immense human and financial costs. In the developed world stroke accounts for around 10 per cent of all deaths and is the most important single cause of severe disability among western people living in their own homes. Futhermore, in the next 30 years, the burden of stroke will grow substantially in most developing nations. There is now substantial evidence that dietary habits not only influence the prevalence of stroke, but also its course and outcome once it has occurred. The author, Salah Gariballa, who has many years’ experience working in this area, carefully presents and reviews this information in a user-friendly and accessible manner. The book is divided into three major sections. Section I covers nutrition and ageing and includes chapters on the challenge of stroke, ageing changes and nutrition, macro- and micronutrient intake in elderly people and the diagnosis of protein-energy undernutrition. Section II deals with nutritional factors and the risk of stroke, and includes details of the role of dietary and nutritional factors in stroke prevention, antioxidants and risk from ischaemic stroke, homocysteine and endothelial dysfunction. The final section of the book covers nutrition factors following stroke, including cerebral ischaemia, protein-energy undernutrition and the nutritional status and support of stroke and special stroke patients. A final chapter looks at probable future directions, including important recommendations. Nutrition and stroke is essential reading for nutritionists, dietitians and many other groups of health professionals, including general practitioners, gerontologists, occupational therapists and nursing staff. Personnel in pharmaceutical and food companies involved in the formulation of dietary supplements and nutraceuticals will find much of interest within the book’s covers. Those dealing with the prevention and treatment of stroke around the world should read this book, and copies should be available in libraries of universities and medical schools worldwide.

DKK 828.00

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Horse Nutrition and Feeding - Sarah Pilliner - Bog - John Wiley and Sons Ltd - Plusbog.dk

Horses have been taken from their natural environment and enclosed in paddocks and stables, dramatically changing both life-style and feeding habits. Feeding time has been greatly reduced and cereal and protein concentrates introduced into the diet. As a result, horses are prone to many problems associated with feeding. This book clearly explains the science of nutrition and combines this with the art of feeding to encourage an understanding of how to feed horses to keep them healthy, and allow them to reach their full performance potential. This new edition - the first since 1992 - has been fully updated and extended to include new feeds and feeding practices and explains new advances in scientific knowledge. It provides clear guidelines for feeding competition horses, older horses and problem animals, and explains the role of feeds and feeding in maintaining the immune system and soundness. Horse Nutrition and Feeding is the recognised text for students studying horses at colleges, for BHS examinations, and for horse-owners.

DKK 474.00

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COVID-19 - H Pennington - Bog - John Wiley and Sons Ltd - Plusbog.dk

Within days of the first reports of patients suffering from a mysterious pneumonia in Wuhan, scientists in China had produced a complete genetic sequence of the virus and confirmed that it was a novel SARS-like coronavirus. The genetic sequence was deposited in a public database, making the genetic code available to scientists anywhere in the world. The result was that weeks before the WHO declared the outbreak a global public health emergency and months before COVID-19 was formally designated a pandemic, virologists around the world were already studying the protein spikes on the virus and designing vaccines, which were developed much more quickly, and turned out to be much more effective, than even the most optimistic had predicted. All of this was possible because a biological revolution had taken place a decade earlier: the world had moved into the postgenomic era. In this book, the distinguished microbiologist Hugh Pennington argues that COVID-19 is the first ‘postgenomic pandemic’ – that is, the first pandemic to sweep the world after the postgenomic era was initiated in 2008. Pennington explains the science behind this crucial development and shows how it has revolutionized our ways of understanding and dealing with pandemics, including the pandemic that brought our world to its knees.

DKK 360.00

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Equine Clinical Nutrition - Rebecca L. Remillard - Bog - John Wiley and Sons Ltd - Plusbog.dk

EQUINE CLINICAL NUTRITION Authoritative resource on the nutritional management of horses, now incorporating the iterative learning process The second edition of Equine Clinical Nutrition is a fully updated and expanded revision of the classic student text on nutritional management of horses, covering updated nutrient recommendations, rations, feeding management, clinical nutrition and many other important topics in the field. To aid in reader comprehension, this new edition takes a new instructional approach to nutritional management using an iterative sequence of defined procedures. Divided into distinct sections for easy accessibility, this book is a comprehensive resource for feeding practices and management of healthy and sick horses alike. A thorough understanding of life stages, anatomy, physiology, and behavior underpins the practice of clinical nutrition. Sample topics covered in Equine Clinical Nutrition include: The evolution of horses to changing food supply, the importance of their microbiome, and the behavior patterns of feeding and drinking Nutrient metabolism of water, energy, protein, minerals, and vitamins, plus ration assessment, farm investigations, forages, and toxic plants Manufactured feeds, dietary supplements, USA feed regulations, and feed safety protocols Nutritional assessment of horses by life stage, recognizing pain and discomfort behaviors, and dietary management of weight and major system disorders Equine Clinical Nutrition is an essential text for students of veterinary medicine, animal science, pre-veterinary programs, and a desk reference for equine practitioners wanting practical clinical feeding recommendations. With comprehensive coverage of the topic, it is an essential text for everything related to nutrition in horses.

DKK 741.00

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Amino Acid Metabolism - David A. Bender - Bog - John Wiley and Sons Ltd - Plusbog.dk

Amino Acid Metabolism, 3 rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other nitrogenous compounds in animals, and the microbiological reactions involved in release of nitrogen gas back into the atmosphere. Mammalian (mainly human) protein and amino acid requirements are considered in detail, and the methods that are used to determine them. Chapters consider individual amino acids, grouped according to their metabolic origin, and discussing their biosynthesis (in plants and micro-organisms for those that are dietary essentials for human beings), major metabolic roles (mainly in human metabolism) and catabolism (again mainly in human metabolism). There is also discussion of regulatory mechanisms for all these metabolic pathways, and of metabolic and genetic diseases affecting the (human) metabolism of amino acids. Throughout the book the emphasis is on the nutritional importance of amino acids, integration and control of metabolism and metabolic and other disturbances of relevance to human biochemistry and health. - - Completely revised edition of this comprehensive text covering all the latest findings in amino acid metabolism research - - Written by an authority in the field - - Covers new advances in structural biology - - Clear illustrations of all structures and metabolic pathways - - Full list of recommended further reading for each chapter and bibliography of papers cited in the text -

DKK 931.00

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Chicken - Paul R. Josephson - Bog - John Wiley and Sons Ltd - Plusbog.dk

Why has the chicken become the meat par excellence, the most plentifully eaten and popular animal protein in the world, consumed from Beijing to Barcelona? As renowned historian Paul Josephson shows, the story of the chicken's rise involves a whole host of factors; from art, to nineteenth-century migration patterns to cold-war geopolitics. And whereas sheep needed too much space, or the cow was difficult to transport, these compact, lightweight birds produced relatively little waste, were easy to transport and could happily peck away in any urban back garden. Josephson tells this story from all sides: the transformation of the chicken from backyard scratcher to hyper-efficient industrial meat-product has been achieved due to the skill of entrepreneurs who first recognized the possibilities of chicken meat and the gene scientists who bred the plumpest and most fertile birds. But it has also been forced through by ruthless capitalists and lobbyists for “big farmer”, at the expense of animal welfare and the environment. With no sign of our lust for chicken abating, we're now reaching a crisis point: billions of birds are slaughtered every year, after having lived lives that are nasty, brutish and short. The waste from these victims is polluting rivers and poisoning animals. We’re now plunging “egg-first” into environmental disaster. Alongside this story Josephson tells another, of an animal with endearing characteristics who, arguably, can lay claim to being man’s best friend long before the dog reared its snout or the cat came in from the cold. Lionized in medieval romances and modern cartoons, the chicken’s relationship to humanity runs deep; by treating these animals as mere food products, we become less than human.

DKK 189.00

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Cancer Chemotherapy - - Bog - John Wiley and Sons Ltd - Plusbog.dk

Provides a clear and accessible summary of all stages and aspects of the discovery, design, development, validation and clinical use of anticancer drugs This new edition provides an update on the current state of the art of cancer chemotherapy and clinical practice and presents new pipeline anticancer agents and promising therapeutic strategies that are emerging alongside new breakthroughs in cancer biology. Its unique approach enables students to gain an understanding of the pathological, physiological, and molecular processes governing malignancy, while also introducing the role of health professionals and scientists in the research and treatment of cancer. Invaluable for its clarity and accessibility, Cancer Chemotherapy: Basic Science to the Clinic, 2nd Edition offers complete coverage of the scientific and clinical aspects of the creation, development, and administration of drugs or drug regimens used in the treatment of the disease. Chapters look at: cancer epidemiology and histopathology; carcinogenesis; current research; tumor hypoxia; antiangiogenic and antivascular agents; protein kinase and Ras blockers; new targets associated with development such as Hedgehog and Wnt signaling; stem cells; immunotherapy and oncolytic viruses; and more. - - Presents a clear, accessible, and comprehensive approach to cancer chemotherapy from basic science to clinical practice - - Offers a major update that reflects the latest developments in personalized chemotherapy - - Provides in-depth coverage of advances in biomarker diagnostics - - Includes new chapters/sections on bioinformatics and the ‘omic sciences’; pharmaceutical strategies used to achieve tumor-selective drug delivery; and cancer cell autophagy - - Combines descriptions of both clinical protocol and explanations of the drug design process in one self-contained book - - Features numerous diagrams and illustrations to enhance reader understanding - Aimed at upper undergraduate, graduate, and medical students, Cancer Chemotherapy: Basic Science to the Clinic, 2nd Edition is also an excellent reference for health professional, especially clinicians specializing in Clinical Oncology, and their patients who want to gain an understanding of cancer and available treatment options.