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Genetic Ties and the Family - - Bog - Johns Hopkins University Press - Plusbog.dk

Genetic Ties and the Family - - Bog - Johns Hopkins University Press - Plusbog.dk

Genetic Ties and the Family brings together experts in history, law, ethics, philosophy, psychology, social work, and sociology to explore the tension between biological and social conceptions of parentage. The contributors consider the effect of DNA-based paternity testing on family relationships and discuss the ethical, legal, and social implications. These essays reflect the changing concepts of parenthood, along with social factors that heighten conflict, such as single-parent adoption, gay and lesbian parents, child support laws, and new reproductive technologies. Building on scholarship of the last quarter century—including the latest developments in law and social science research—this volume will inform the development of legislation regulating genetic testing and the use of test results in establishing parental rights. Contributors: Lori B. Andrews, J.D., Chicago-Kent College of Law; Elizabeth Bartholet, J.D., Harvard Law School; Jeffrey Blustein, Ph.D., Albert Einstein College of Medicine; Nancy E. Dowd, J.D., Levin College of Law, University of Florida; Michael Grossberg, Ph.D., Indiana University; Dorothy Nelkin, B.A., New York University; Jeffrey Parness, J.D., North Illinois University College of Law; Dianne Scott-Jones, Ph.D., Boston College; Daniel Wulff, Ph.D., Raymond A. Kent School of Social Work, University of Louisville.

DKK 485.00
1

The Invention of the Modern Dog - Neil (chstm Pemberton - Bog - Johns Hopkins University Press - Plusbog.dk

The Invention of the Modern Dog - Neil (chstm Pemberton - Bog - Johns Hopkins University Press - Plusbog.dk

The story of the thoroughly Victorian origins of dog breeds. For centuries, different types of dogs were bred around the world for work, sport, or companionship. But it was not until Victorian times that breeders started to produce discrete, differentiated, standardized breeds. In The Invention of the Modern Dog, Michael Worboys, Julie-Marie Strange, and Neil Pemberton explore when, where, why, and how Victorians invented the modern way of ordering and breeding dogs. Though talk of "breed" was common before this period in the context of livestock, the modern idea of a dog breed defined in terms of shape, size, coat, and color arose during the Victorian period in response to a burgeoning competitive dog show culture. The authors explain how breeders, exhibitors, and showmen borrowed ideas of inheritance and pure blood, as well as breeding practices of livestock, horse, poultry and other fancy breeders, and applied them to a species that was long thought about solely in terms of work and companionship. The new dog breeds embodied and reflected key aspects of Victorian culture, and they quickly spread across the world, as some of Britain’s top dogs were taken on stud tours or exported in a growing international trade. Connecting the emergence and development of certain dog breeds to both scientific understandings of race and blood as well as Britain’s posture in a global empire, The Invention of the Modern Dog demonstrates that studying dog breeding cultures allows historians to better understand the complex social relationships of late-nineteenth-century Britain.

DKK 233.00
1

The Invention of the Modern Dog - Julie Marie (history Strange - Bog - Johns Hopkins University Press - Plusbog.dk

The Invention of the Modern Dog - Julie Marie (history Strange - Bog - Johns Hopkins University Press - Plusbog.dk

The story of the thoroughly Victorian origins of dog breeds. For centuries, different types of dogs were bred around the world for work, sport, or companionship. But it was not until Victorian times that breeders started to produce discrete, differentiated, standardized breeds. In The Invention of the Modern Dog, Michael Worboys, Julie-Marie Strange, and Neil Pemberton explore when, where, why, and how Victorians invented the modern way of ordering and breeding dogs. Though talk of "breed" was common before this period in the context of livestock, the modern idea of a dog breed defined in terms of shape, size, coat, and color arose during the Victorian period in response to a burgeoning competitive dog show culture. The authors explain how breeders, exhibitors, and showmen borrowed ideas of inheritance and pure blood, as well as breeding practices of livestock, horse, poultry and other fancy breeders, and applied them to a species that was long thought about solely in terms of work and companionship. The new dog breeds embodied and reflected key aspects of Victorian culture, and they quickly spread across the world, as some of Britain’s top dogs were taken on stud tours or exported in a growing international trade. Connecting the emergence and development of certain dog breeds to both scientific understandings of race and blood as well as Britain’s posture in a global empire, The Invention of the Modern Dog demonstrates that studying dog breeding cultures allows historians to better understand the complex social relationships of late-nineteenth-century Britain.

DKK 355.00
1

Ethics and Newborn Genetic Screening - - Bog - Johns Hopkins University Press - Plusbog.dk

Ethics and Newborn Genetic Screening - - Bog - Johns Hopkins University Press - Plusbog.dk

Highly Commended, Basis of Medicine, 2010 British Medical Association Book Awards The United States has the first and the farthest-reaching newborn genetic screening program in the world. In recent years, individual states have expanded their newborn screening programs to include many more genetic conditions, as new medical knowledge and new testing technologies have become available. The contributors to this provocative collection study the complex ethical and policy challenges present in the changing newborn screening environment and offer guidance to professionals, policymakers, and the general public. Experts from the fields of bioethics, genetics, pediatrics, public health, health policy, law, and political science identify and analyze four social and ethical issues critical to newborn screening policy: the distribution of costs and benefits; information, consent, and privacy; consultation and decision making; and race, ethnicity, and socioeconomic status. In the process, the contributors capture the difficulties of trying to forge ethical public policy at the intersection of parental concerns, new technologies, and economic interests. Contributors: Andrea Bonnicksen, Ph.D., Northern Illinois University; Jeffrey R. Botkin, M.D., M.P.H., University of Utah; Ned Calonge, M.D., M.P.H., Department of Public Health and Environment, Denver; Toby Citrin, J.D., University of Michigan School of Public Health; Ellen Wright Clayton, M.D., M.S., J.D., Vanderbilt University; Jannine De Mars Cody, Ph.D., University of Texas Health Science Center; Anne Marie Comeau, Ph.D., University of Massachusetts Medical School; James R. Eckman, M.D., Emory University School of Medicine; Scott D. Grosse, Ph.D., National Center on Birth Defects and Developmental Disabilities; Bruce Jennings, M.A., Yale School of Public Health; Donna E. Levin, J.D., Massachusetts Department of Public Health; Michele A. Lloyd-Puryear, M.D., Ph.D., U.S. Department of Health and Human Services; Marie Y. Mann, M.D., M.P.H., U.S. Department of Health and Human Services; Karen J. Maschke, Ph.D., The Hastings Center; Stephen M. Modell, M.D., M.S., University of Michigan School of Public Health; Virginia A. Moyer, M.D., M.P.H., Baylor College of Medicine and Texas Children''s Hospital; Lainie Friedman Ross, M.D., Ph.D., University of Chicago; Joseph Telfair, Dr.P.H., M.S.W., M.P.H., University of North Carolina at Greensboro; Steven M. Teutsch, M.D., M.P.H., Merck & Co., Inc.; Bradford L. Therrell, Ph.D., University of Texas Health Science Center; Benjamin S. Wilfond, M.D., University of Washington

DKK 472.00
1

Living with Hereditary Cancer Risk - Sue Friedman - Bog - Johns Hopkins University Press - Plusbog.dk

Living with Hereditary Cancer Risk - Sue Friedman - Bog - Johns Hopkins University Press - Plusbog.dk

The most comprehensive guide available on hereditary cancers, from understanding risk, prevention, and genetic counseling and testing to treatment, quality of life, and more. Up to 10 percent of cancers are caused by inherited mutations in specific genes. Finding out that you or your loved ones may be at increased risk of developing cancer because of a genetic mutation raises a lot of questions: Is cancer inevitable? Is there anything I should do differently in my life? Will my children also be at higher risk of cancer? Should I have preemptive treatments or surgery? This comprehensive guide provides answers to these questions and more. Written by three passionate patient advocates, this book is a compilation of the trusted information and support provided for more than two decades by Facing Our Risk of Cancer Empowered (FORCE), the de facto voice of the hereditary cancer community. Combining the latest scientific research with national guidelines, expert advice, and compelling patient stories, the book offers previvors (those who have a mutation but have never been diagnosed), survivors, and their families the guidance they need to face the unique physical and emotional challenges of living in a high-risk body. An ideal resource for genetic counselors, physicians, nurses, advocates, and others who support and care for the hereditary cancer community, Living with Hereditary Cancer Risk also provides coverage of • signs of inherited cancer risk in a family;• the value of genetic counseling and testing;• mutations in BRCA, Lynch Syndrome, and other genes that elevate cancer risk; • risk-reducing strategies; • traditional treatments and newer personalized approaches, including immunotherapies and PARP inhibitors; • nationally recommended guidelines for prevention, early detection, and treatment; • insurance coverage and discrimination protections; and• coping with sexual health, fertility, menopause, and other quality of life issues.

DKK 242.00
1

Living with Hereditary Cancer Risk - Sue Friedman - Bog - Johns Hopkins University Press - Plusbog.dk

Living with Hereditary Cancer Risk - Sue Friedman - Bog - Johns Hopkins University Press - Plusbog.dk

The most comprehensive guide available on hereditary cancers, from understanding risk, prevention, and genetic counseling and testing to treatment, quality of life, and more. Up to 10 percent of cancers are caused by inherited mutations in specific genes. Finding out that you or your loved ones may be at increased risk of developing cancer because of a genetic mutation raises a lot of questions: Is cancer inevitable? Is there anything I should do differently in my life? Will my children also be at higher risk of cancer? Should I have preemptive treatments or surgery? This comprehensive guide provides answers to these questions and more. Written by three passionate patient advocates, this book is a compilation of the trusted information and support provided for more than two decades by Facing Our Risk of Cancer Empowered (FORCE), the de facto voice of the hereditary cancer community. Combining the latest scientific research with national guidelines, expert advice, and compelling patient stories, the book offers previvors (those who have a mutation but have never been diagnosed), survivors, and their families the guidance they need to face the unique physical and emotional challenges of living in a high-risk body. An ideal resource for genetic counselors, physicians, nurses, advocates, and others who support and care for the hereditary cancer community, Living with Hereditary Cancer Risk also provides coverage of • signs of inherited cancer risk in a family;• the value of genetic counseling and testing;• mutations in BRCA, Lynch Syndrome, and other genes that elevate cancer risk; • risk-reducing strategies; • traditional treatments and newer personalized approaches, including immunotherapies and PARP inhibitors; • nationally recommended guidelines for prevention, early detection, and treatment; • insurance coverage and discrimination protections; and• coping with sexual health, fertility, menopause, and other quality of life issues.

DKK 419.00
1

The Troubled Dream of Genetic Medicine - Keith Wailoo - Bog - Johns Hopkins University Press - Plusbog.dk

The Troubled Dream of Genetic Medicine - Keith Wailoo - Bog - Johns Hopkins University Press - Plusbog.dk

Winner of the History of Science category of the Professional and Scholarly Publishing Awards given by the Association of American Publishers Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a "Caucasian" disease; and sickle cell disease, widely associated with African Americans. In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these diseases—fraught with ethnic and racial meanings for many Americans—became objects of biological fascination and crucibles of social debate. Peering behind the headlines of breakthrough treatments and coming cures, they tell a complex story: about different kinds of suffering and faith, about unequal access to the promises and perils of modern medicine, and about how Americans consume innovation and how they come to believe in, or resist, the notion of imminent medical breakthroughs. With Tay-Sachs, cystic fibrosis, and sickle cell disease as a powerful backdrop, the authors provide a glimpse into a diverse America where racial ideologies, cultural politics, and conflicting beliefs about the power of genetics shape disparate health care expectations and experiences.

DKK 273.00
1

Genomics and Environmental Regulation - - Bog - Johns Hopkins University Press - Plusbog.dk

Genomics and Environmental Regulation - - Bog - Johns Hopkins University Press - Plusbog.dk

To reduce the deleterious effects of environmental contamination, governments across the world have enacted regulations broadly conceived for entire populations. Information arising out of the Human Genome Project and other cutting-edge genetic research is shifting the policymaking process. This fascinating volume draws on experts from academia, government, industry, and nongovernmental organizations to examine the science of genomic research as applied to environmental policy. The first section explores environmental policy applications, including subpopulation genetic profiling, industrial regulations, and standardizing governmental evaluation of genomic data. The second section assesses from multiple angles the legal framework involved in applying genomics to environmental regulation. In the third section, the contributors review closely the implications of genomic research for occupational health, from disease prevention and genetic susceptibility to toxicants, to workers’ rights and potential employment discrimination. A fourth section explores the bioethical and philosophical complications of bringing genetic data and research into nonclinical regulatory frameworks. Genomics and Environmental Regulation points to ways in which information on toxicology and genetics can be used to craft more precise and efficient regulations.

DKK 472.00
1

The Promise and Peril of CRISPR - - Bog - Johns Hopkins University Press - Plusbog.dk

The Promise and Peril of CRISPR - - Bog - Johns Hopkins University Press - Plusbog.dk

A timely collection of essays on the pressing possibilities and risks of gene-editing technology. Scientists and genetic engineers are becoming increasingly adept at editing the human genome. How far can—and should—they go in editing future generations? In The Promise and Peril of CRISPR, editor Neal Baer brings together a timely collection of essays by influential bioethicists, philosophers, and geneticists to explore the moral, ethical, and policy challenges posed by CRISPR technology. We are at a technological and ethical crossroads in grappling with the impacts of genetic editing. Gene-editing technology holds the promise of curing more than 7,000 known genetic diseases. Yet with that promise comes the peril of using CRISPR to edit the human genome, which could not only lead to manipulating human evolution, but also to creating and releasing pathogens capable of wreaking havoc on human, animal, and plant life. Although CRISPR has already cured several genetic diseases, it could also be used to design biological weapons or to edit the embryos of people who can afford to purchase genetic "enhancements" for their children. What role can and should the public play in discussing the far-reaching implications of gene editing? What oversights should be put in place to prevent a rogue scientist from engineering another baby – as was recently done with twins in China?Essay contributors offer informed predictions and guidelines for how the uses of CRISPR today will affect life in the future. Decisions we make now may have unpredictable consequences for future generations. For anyone concerned about the uses and potential abuses of gene editing, these essays provide a critical and comprehensive discussion of the central issues surrounding CRISPR technology. Contributors: Florence Ashley, R. Alta Charo, Marcy Darnovsky, Kevin Doxzen, Rosemarie Garland-Thomson, Gigi Kwik Gronvall, Jodi Halpern, Katie Hasson, Andrew C. Heinrich, Jacqueline Humphries, J. Benjamin Hurlbut, Ellen D. Jorgensen, Peter F. R. Mills, Carol Padden, Marcus Schultz-Bergin, Robert Sparrow, Sandra Sufian, Krystal Tsosie, Ethan Weiss, Rachel M. West

DKK 401.00
1