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Finding a Path to Safety in Food Allergy - Health And Medicine Division - Bog - National Academies Press - Plusbog.dk

Finding a Path to Safety in Food Allergy - Health And Medicine Division - Bog - National Academies Press - Plusbog.dk

Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health. Table of ContentsFront MatterSummary1 Introduction2 Definitions3 Prevalence4 Assessments, Diagnostic Testing, Disease Monitoring, and Prognosis5 Potential Genetic and Environmental Determinants of Food Allergy Risk and Possible Prevention Strategies6 Management in the Health Care Setting7 Management of Packaged Foods8 Managing Food Allergies in Retail, Food Service, Schools, Higher Education, and Travel Settings9 Research Needs10 Final Comments: A Roadmap to SafetyAppendix A: Open Session AgendasAppendix B: Food Allergy Prevalence Literature Search StrategyAppendix C: Risk Determinants Literature Search StrategyAppendix D: Acronyms and AbbreviationsAppendix E: DefinitionsAppendix F: Committee Members Biographical Sketches

DKK 474.00
1

Toxicity Testing for Assessment of Environmental Agents - Committee On Toxicity Testing And Assessment Of Environmental Agents - Bog - National

Toxicity Testing for Assessment of Environmental Agents - Committee On Toxicity Testing And Assessment Of Environmental Agents - Bog - National

Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants. Table of ContentsFront MatterSummary1 Introduction2 Animal and In Vitro Toxicity Testing3 Human Data4 Strategies for Toxicity Testing5 Use of Data in Human Health Risk Assessment6 New Approaches7 Alternative Approaches and Emerging TechnologiesAppendix A: Biographic information on the Committee on Toxicity Testing and Assessment of Environmental Agents Appendix B: Testing Protocols

DKK 545.00
1

Enhancing Food Safety - Committee On The Review Of The Food And Drug Administration's Role In Ensuring Safe Food - Bog - National Academies Press -

Enhancing Food Safety - Committee On The Review Of The Food And Drug Administration's Role In Ensuring Safe Food - Bog - National Academies Press -

Recent outbreaks of illnesses traced to contaminated sprouts and lettuce illustrate the holes that exist in the system for monitoring problems and preventing foodborne diseases. Although it is not solely responsible for ensuring the safety of the nation's food supply, the U.S. Food and Drug Administration (FDA) oversees monitoring and intervention for 80 percent of the food supply. The U.S. Food and Drug Administration's abilities to discover potential threats to food safety and prevent outbreaks of foodborne illness are hampered by impediments to efficient use of its limited resources and a piecemeal approach to gathering and using information on risks. Enhancing Food Safety: The Role of the Food and Drug Administration, a new book from the Institute of Medicine and the National Research Council, responds to a congressional request for recommendations on how to close gaps in FDA's food safety systems. Enhancing Food Safety begins with a brief review of the Food Protection Plan (FPP), FDA's food safety philosophy developed in 2007. The lack of sufficient detail and specific strategies in the FPP renders it ineffectual. The book stresses the need for FPP to evolve and be supported by the type of strategic planning described in these pages. It also explores the development and implementation of a stronger, more effective food safety system built on a risk-based approach to food safety management. Conclusions and recommendations include adopting a risk-based decision-making approach to food safety; creating a data surveillance and research infrastructure; integrating federal, state, and local government food safety programs; enhancing efficiency of inspections; and more. Although food safety is the responsibility of everyone, from producers to consumers, the FDA and other regulatory agencies have an essential role. In many instances, the FDA must carry out this responsibility against a backdrop of multiple stakeholder interests, inadequate resources, and competing priorities. Of interest to the food production industry, consumer advocacy groups, health care professionals, and others, Enhancing Food Safety provides the FDA and Congress with a course of action that will enable the agency to become more efficient and effective in carrying out its food safety mission in a rapidly changing world. Table of ContentsFront MatterSummaryPart I: Setting the Stage for Understanding and Improving the U.S. Food and Drug Administration's Role in the Food Safety System1 Introduction2 The Food Safety System: Context and Current StatusPart II: Toward a Stronger and More Effective Food Safety System3 Adopting a Risk-Based Decision-Making Approach to Food Safety4 Sharing the Responsibility for a Risk-Based System: Models of Governance and OversightPart III: Implementation of the New Food Safety System5 Creating an Integrated Information Infrastructure for a Risk-Based Food Safety System6 Creating a Research Infrastructure for a Risk-Based Food Safety System7 Integrating Federal, State, and Local Government Food Safety Programs8 Enhancing the Efficiency of Inspections9 Improving Food Safety and Risk Communication10 Modernizing Legislation to Enhance the U.S. Food Safety System11 Achieving the Vision of an Efficient Risk-Based Food Safety SystemAppendix A: Workshop AgendasAppendix B: Past Recommendations About the U.S. Food and Drug Administration's Food Safety ProgramAppendix C: Food Safety Systems in the United States and Other CountriesAppendix D: The U.S. Food and Drug Administration's Food Defense ProgramAppendix E: The U.S. Food and Drug Administration and Imported Food SafetyAppendix F: Food Safety Research at Intramural and Extramural U.S. Food and Drug Administration Research Centers, by TopicAppendix G: U.S. Food and Drug Administration Food Protection PlanAppendix H: GlossaryAppendix I: Acronyms and AbbreviationsAppendix J: Committee Member Biographical Sketches

DKK 474.00
3

Testing at the Speed of Light - Committee On Space Radiation Effects Testing Infrastructure For The U.s. Space Program - Bog - National Academies

Testing at the Speed of Light - Committee On Space Radiation Effects Testing Infrastructure For The U.s. Space Program - Bog - National Academies

Spacecraft depend on electronic components that must perform reliably over missions measured in years and decades. Space radiation is a primary source of degradation, reliability issues, and potentially failure for these electronic components. Although simulation and modeling are valuable for understanding the radiation risk to microelectronics, there is no substitute for testing, and an increased use of commercial-off-the- shelf parts in spacecraft may actually increase requirements for testing, as opposed to simulation and modeling. Testing at the Speed of Light evaluates the nation's current capabilities and future needs for testing the effects of space radiation on microelectronics to ensure mission success and makes recommendations on how to provide effective stewardship of the necessary radiation test infrastructure for the foreseeable future. Table of ContentsFront MatterSummary1 Introduction2 The Space Radiation Environment and Its Effect on Electronics3 Current State of Single-Event Effects Hardness Assurance and Infrastructure4 Future Infrastructure Needs5 A Path Toward the FutureAppendixesAppendix A: Statement of TaskAppendix B: Single-Event Effects Testing Facilities in the United StatesAppendix C: AcronymsAppendix D: Sources for Further ReadingAppendix E: Committee and Staff BiographiesAppendix F: Speakers Before the Committee

DKK 422.00
1

Managing Food Safety Practices from Farm to Table - Food Forum - Bog - National Academies Press - Plusbog.dk

Testing English-Language Learners in U.S. Schools: Report and Workshop Summary - National Research Council

Data and Research to Improve the U.S. Food Availability System and Estimates of Food Loss: A Workshop Summary - Bog af National Research Council - Pap

Testing of Body Armor Materials - Board On Army Science And Technology - Bog - National Academies Press - Plusbog.dk

Testing of Body Armor Materials - Board On Army Science And Technology - Bog - National Academies Press - Plusbog.dk

In 2009, the Government Accountability Office (GAO) released the report Warfighter Support: Independent Expert Assessment of Army Body Armor Test Results and Procedures Needed Before Fielding, which commented on the conduct of the test procedures governing acceptance of body armor vest-plate inserts worn by military service members. This GAO report, as well as other observations, led the Department of Defense Director, Operational Test & Evaluation, to request that the National Research Council (NRC) Division on Engineering and Physical Sciences conduct a three-phase study to investigate issues related to the testing of body armor materials for use by the U.S. Army and other military departments. Phase I and II resulted in two NRC letter reports: one in 2009 and one in 2010. This report is Phase III in the study. Testing of Body Armor Materials: Phase III provides a roadmap to reduce the variability of clay processes and shows how to migrate from clay to future solutions, as well as considers the use of statistics to permit a more scientific determination of sample sizes to be used in body armor testing. This report also develops ideas for revising or replacing the Prather study methodology, as well as reviews comments on methodologies and technical approaches to military helmet testing. Testing of Body Armor Materials: Phase III also considers the possibility of combining various national body armor testing standards.

DKK 396.00
3