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Innovation for the 21st Century - Michael A. Carrier - Bog - Oxford University Press Inc - Plusbog.dk

Innovation for the 21st Century - Michael A. Carrier - Bog - Oxford University Press Inc - Plusbog.dk

Type 1 Diabetes in Adults - Barbara Simon - Bog - Oxford University Press Inc - Plusbog.dk

Type 1 Diabetes in Adults - Barbara Simon - Bog - Oxford University Press Inc - Plusbog.dk

At a time of dramatic increases in the prevalence of obesity, it is appropriate that Type 2 diabetes has received a great deal of attention by the endocrinology community. Clearly, the management of insulin resistance and cardiovascular risk is a critical issue. However, it is important to also acknowledge and address Type 1 diabetes, whose prevalence is also increasing, and whose management remains complex. Currently it is estimated that 10-15% of those with diabetes carry the diagnosis of Type 1 diabetes, and frequently the diagnosis is not straightforward, as many clinicians recognize that more adults previously thought to have Type 2 diabetes actually have late-onset Type 1 diabetes (also termed latent autoimmune diabetes of the adult or LADA). Over the last decade tools for the management of Type 1 diabetes have also evolved; therefore, clinicians now have the opportunity to more closely replicate normal physiologic insulin secretion with either basal-bolus insulin therapy or continuous subcutaneous insulin infusions. While these advancements allow clinicians to manage patients with Type 1 diabetes better, they also add complexity to patient treatment. An updated text to address the concepts behind the recognition of new onset Type 1 diabetes in adults, the ongoing care of adults with established Type 1 diabetes, and future potential therapies and devices is warranted to review these issues for both endocrinologists and primary care providers with an interest in diabetes. As part of the Oxford American Endocrinology Library, this volume stands as a concise guide in the treatment of Type 1 Diabetes in adults. The authors briefly examine the classification and pathophysiology of Type 1 diabetes (including predication and prevention and LADA) and address management (blood glucose monitoring, insulin therapy, and Continuous Subcutaneous Insulin Infusion) and complications (Hyperglycemia, Retinocpathy, Nephropathy, Neuropathy, etc) of the disease. Finally and perhaps most significantly, the authors consider "special situations" associated with Type 1 Diabetes patients, including inpatient treatment, pancreas and inslet transplantation, and how to treat pregnant and depressed patients and patients with eating disorders.

DKK 469.00
1

Obesity and Type 2 Diabetes Mellitus - John P. Sheehan - Bog - Oxford University Press Inc - Plusbog.dk

Obesity and Type 2 Diabetes Mellitus - John P. Sheehan - Bog - Oxford University Press Inc - Plusbog.dk

With the advent of the worldwide obesity epidemic, a concurrent rise has occurred in the prevalence of type 2 diabetes mellitus and metabolic syndrome. Type 2 diabetes mellitus is affecting younger individuals-the disease is no longer exclusive to adulthood. Diabetic micro- and macrovascular complications are also occurring at an earlier age, leading to increasing demands and costs on the healthcare system. In addition, the morbidity, disability and premature death caused by diabetic complications create a huge burden to families, employers and society at large. Thankfully, there has been a tremendous growth in new therapeutic classes of medications to help manage type 2 diabetes mellitus. These agents target many of the pathophysiologic defects of the disease with fewer side effects than the older agents. Newer insulin formulations have more predictable kinetics so patients can achieve better glycemic control with less risk of hypoglycemia and weight gain. Insulin delivery devices have also improved to include higher quality insulin pens, finer and shorter pen needles, and more technologically advanced insulin pumps. As part of the Oxford American Endocrinology Library series, this handbook reviews the epidemiology and pathophysiology of obesity and type 2 diabetes mellitus. The content covers micro- and macrovascular diabetic complications, the array of glucose regulating therapies, treatment algorithms targeting the pathophysiologic defects of type 2 diabetes mellitus as well as strategies for macrovascular risk reduction via therapeutic lifestyle change (diet, exercise, smoking cessation), pharmacotherapeutic treatment of dyslipidemia and hypertension, bariatric surgery and subcutaneous insulin infusion therapy, among other topics. Because of the concise yet comprehensive nature of the handbook, this volume is an excellent point-of-care reference for the clinician who regulary treats obese and diabetic patients.

DKK 388.00
1

The Battle of Midway - Craig L. (professor Of History Symonds - Bog - Oxford University Press Inc - Plusbog.dk

The Battle of Midway - Craig L. (professor Of History Symonds - Bog - Oxford University Press Inc - Plusbog.dk

There are few moments in American history in which the course of events tipped so suddenly and so dramatically as at the Battle of Midway. At dawn of June 4, 1942, a rampaging Japanese navy ruled the Pacific. By sunset, their vaunted carrier force (the Kido Butai) had been sunk and their grip on the Pacific had been loosened forever. In this riveting account of a key moment in the history of World War II, one of America''s leading naval historians, Craig L. Symonds, paints an unforgettable portrait of ingenuity, courage, and sacrifice. Symonds begins with the arrival of Admiral Chester A. Nimitz at Pearl Harbor after the devastating Japanese attack, and describes the key events leading to the climactic battle, including both Coral Sea--the first battle in history against opposing carrier forces--and Jimmy Doolittle''s daring raid of Tokyo. He focuses throughout on the people involved, offering telling portraits of Admirals Nimitz, Halsey, Spruance and numerous other Americans, as well as the leading Japanese figures, including the poker-loving Admiral Yamamoto. Indeed, Symonds sheds much light on the aspects of Japanese culture--such as their single-minded devotion to combat, which led to poorly armored planes and inadequate fire-safety measures on their ships--that contributed to their defeat. Symond''s account of the battle itself is masterful, weaving together the many disparate threads of attack--attacks which failed in the early going--that ultimately created a five-minute window in which three of the four Japanese carriers were mortally wounded, changing the course of the Pacific war in an eye-blink.Symonds is the first historian to argue that the victory at Midway was not simply a matter of luck, pointing out that Nimitz had equal forces, superior intelligence, and the element of surprise. Nimitz had a strong hand, Symonds concludes, and he rightly expected to win.

DKK 222.00
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Laughing Gas, Viagra, and Lipitor - Jie Jack (medicinal Chemist Li - Bog - Oxford University Press Inc - Plusbog.dk

Laughing Gas, Viagra, and Lipitor - Jie Jack (medicinal Chemist Li - Bog - Oxford University Press Inc - Plusbog.dk

The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated with them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind - for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections.Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true.The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

DKK 447.00
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Foundations of Perinatal Genetic Counseling - Ms Amber Mathiesen - Bog - Oxford University Press Inc - Plusbog.dk

Mental Retardation and Developmental Delay - Moyra Smith - Bog - Oxford University Press Inc - Plusbog.dk

Mental Retardation and Developmental Delay - Moyra Smith - Bog - Oxford University Press Inc - Plusbog.dk

Recent advances in neuroscience and genetics have greatly expanded our understanding of the brain and of the etiological factors involved in developmental delay and mental retardation. At the same time, the human genome project has yielded a wealth of information on DNA sequencing, regulation of gene expression, epigenetics, and functional aspects of the genome, which newly propels investigation into the pathogenesis of mental retardation. This book makes readily available current knowledge on the subject and applies it to clinical medicine, providing information essential to neurologists, geneticists, physicians and pediatricians as they search for the causes of mental handicap in their patients. Introductory chapters cover normal and abnormal brain structure, neurogenesis, neuronal proliferation, and signal transduction. Latter chapters delve into discussions of both the environmental factors that may lead to neurocognitive deficits and the cytogenetic, biochemical and molecular defects specifically associated with mental retardation. One chapter reviews gene involvement in non-syndromic mental retardation, autism, and language deficits, as well as multifactorial and genetically complex inheritance. The text concludes with a clinically practical discussion of carrier detection, presymptomatic diagnosis, and treatment of various genetic diseases through enzyme therapy, substrate deprivation, and the use of hemapoietic stem cells.

DKK 881.00
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Caring for the Family Caregiver - Joy Goldsmith - Bog - Oxford University Press Inc - Plusbog.dk

Caring for the Family Caregiver - Joy Goldsmith - Bog - Oxford University Press Inc - Plusbog.dk

Caring for the Family Caregiver examines the high cost and poorly addressed exigencies of the family caregiver in chronic illness, including health literacy, palliative care, and health outcomes, through the prism of communication. This book uses an interdisciplinary approach to identify the impact of communication and its burdens on the caregiver and presents four caregiver profiles: the Manager, Carrier, Partner, and Lone caregiver, each emerging from a family system with different patterns of conversational sharing and expectations of conformity. By synthesizing current data assessing the experiences of caregivers, as well as integrating the narrative experiences of a range of caregivers living through a variety of illnesses and their specific demands, the authors deliver an unflinching gaze at the journey of the caregiver.With an author team comprised of three health communication researchers and a nurse and health literacy expert, this volume integrates literature addressing caregiver needs and burdens, communication theory and practice, palliative care and health literacy research, and the real stories of caregivers. Caring for the Family Caregiver presents the groundbreaking concept of the Caregiver Types and an innovative set of support resources to facilitate improved pathways to better care for the caregiver, making it an essential resource for providers, students, clinicians, policy makers and family caregivers alike.

DKK 456.00
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American Journalists - Donald A. Ritchie - Bog - Oxford University Press Inc - Plusbog.dk

American Journalists - Donald A. Ritchie - Bog - Oxford University Press Inc - Plusbog.dk

In 60 essays, this volume profiles American journalists from colonial times to the present--reporters, editors, publishers, photographers, and broadcasters--whose careers reflected major developments in their profession and in the history of the United States. In a speech to Newsweek correspondents in 1963, publisher Philip Graham described journalism as "the first rough draft of history." These journalists confronted and helped to shape the discussion of major issues and events in American history, from the American revolution through abolition, westward expansion, the Civil War, the civil rights movement, immigration, and the women''s movement, as well as major constitutional issues involving the First Amendment protection of freedom of the press. Biographies of well-known journalists, from Benjamin Franklin and Thomas Paine to Walter Cronkite and Rupert Murdoch, appear alongside some who may be less familiar, such as Elias Boudinot, founder of the first Cherokee language newspaper; Abraham Cahan, editor of the Jewish Daily Forward; and Daniel Craig, who in the 1830s used carrier pigeons to ferry the news. Other subjects include Margaret Green Draper, the revolutionary printer; Claude Barnett, founder of the Associated Negro Press; photojournalist Margaret Bourke-White; war correspondent Ernie Pyle; and Allen Neuharth, founder of USA Today. Illustrations, fact boxes, and quotations from the subjects themselves make this volume an indispensable reference for students of American history as well as a fascinating read. Journalists profiled include: Horace Greeley Frederick Douglass Mark Twain Thomas Nast Joseph Pulitzer Nellie Bly William Randolph Hearst Ida Wells-Barnett H. L. Mencken Dorothy Thompson Walter Winchell Red Smith Edward R. Murrow Walter Cronkite Bernard Shaw Cokie Roberts Manuel de Dios Unanue and many more

DKK 249.00
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Diabetes: Improving Patient Care - Vivan Fonseca - Bog - Oxford University Press Inc - Plusbog.dk

Diabetes: Improving Patient Care - Vivan Fonseca - Bog - Oxford University Press Inc - Plusbog.dk

Over 20 million people in the United States have diabetes, a metabolic disorder characterized by the body's lack of production or ineffective use of insulin, and the rate is on the rise. Diabetes can cause acute, as well as long-term complications when not properly controlled. Some of the complications may include coma, cardiovascular disease, renal failure, blindness, nerve damage, vascular damage, and poor healing which can lead to amputation. Though there is no cure for either Type I or Type II diabetes, ongoing effort to develop new drug and gene therapies continues. In the meantime, the goals of treatment are disease management, prevention of complications, and improved quality of life. The choice of therapeutics varies by diabetes type and may depend on other significant factors. The selected regimen often includes medication, injection therapy, exercise and change in diet. Over the past few decades, awareness of the importance of early diagnosis and treatment of diabetes has increased significantly. With approximately one-third of those affected by diabetes unaware of their illness, it is critical to make every effort to identify the disease early in its course. The primary care physician is frequently the first to see patients presenting with pre-diabetes and diabetes symptoms. This highly practical volume is specifically designed for primary care physicians and internists on the frontlines of care. It provides a clinically-focused roadmap to providing optimal care for patients with pre-diabetes and diabetes, from the initial patient visit through testing, goal-setting and follow-up care. It offers up-to-date information on diagnosis and treatment options for all types of diabetes, helping to expedite delivery of appropriate care. Part of the new Oxford American Endocrinology Library, this concise yet comprehensive guide covers current approaches and new developments in the diagnosis, management and treatment of diabetes, including Type I, Type II, and gestational diabetes, as well as additional notes on pre-diabetes. The text covers new and emerging pharmacotherapies and complementary treatment guidelines, as well as valuable guidance on managing the major complications of diabetes. In addition to diet and exercise tips for patients, the guide also provides strategies and tools for inspiring healthier lifestyles and patient compliance to reach health goals.

DKK 467.00
1

Justice, Migration, and Mercy - Michael (professor Of Philosophy Blake - Bog - Oxford University Press Inc - Plusbog.dk

Justice, Migration, and Mercy - Michael (professor Of Philosophy Blake - Bog - Oxford University Press Inc - Plusbog.dk

Political controversy about migration is becoming more frequent, more heated, and for certain groups, decidedly more urgent. This raises pressing questions not only in the realms of policy-making and public discourse, but also for philosophical accounts of migration. Do liberal states have the right to exclude unwanted outsiders, or should all borders be open? How should we begin to theorize the morality of refugee and asylum policy? If states can exclude unwanted outsiders, what ethical principles govern the determination of who gets in? Justice, Migration, and Mercy offers a way in which these questions might be answered by providing a vision of how we can understand the political morality of migration. Michael Blake offers a novel, and plausible, account of the right to exclude on which that right is grounded on a more fundamental right to avoid unwanted forms of political relationship. Far from simply justifying exclusion, however, Blake examines the best justifications for exclusion in an effort to determine its limits. In doing so, he challenges the current global realities of migration which ensure open borders for a select few and closed borders for the majority, most often the most marginalized in society. His account sheds light on more specific questions of justice in migration, such as the permissibility of travel bans and carrier sanctions. He also offers a particular vision about how to go beyond questions of right and liberal justice, towards a declaration of the sort of community we wish to be. Blake then identifies the moral notion of mercy as a central one for the moral analysis of migration, a move which leads to the conclusion that we ought to show mercy and justice in constructing migration policy as well as in public debate.

DKK 222.00
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The Decarbonization Delusion - Andrew Moore - Bog - Oxford University Press Inc - Plusbog.dk

The Decarbonization Delusion - Andrew Moore - Bog - Oxford University Press Inc - Plusbog.dk

Could the race to de-carbonize our energy systems be leading us closer to environmental disaster?Why did biology choose carbon, in a variety of compounds, as its energy carrier and storage substance? From the smallest life forms, through multicellular organisms, and up to whole ecosystems, this economy of carbon compounds is fundamentally sustainable. Yet today, many are working to expunge carbon-based energy carriers from human economies, replacing them with solutions based on other elements and minerals. In The Decarbonization Delusion, independent scientist and writer Andrew Moore shows that the race to decarbonize is leading us further down the road to environmental degradation. Instead of banishing carbon, Moore argues that we should look to life on Earth, which has used carbon in highly sustainable ways for 3.5 billion years, as a model for how humans can use carbon sustainably.The Decarbonization Delusion begins by discussing carbon''s role in the inception of the universe and its critical importance in biology. Moore identifies many intriguing features of biology''s use of carbon that are crucial to creating sustainable human economies on Earth. Throughout, Moore draws on extensive research and original calculations to disprove common fallacies about carbon-based energy carriers and their alternatives. For example, he shows that the widely perceived superiority of battery technology over carbon-based fuels is, in most regards, a serious misconception that, if not corrected, could have grave environmental consequences.Politicians, industrial leaders, and even some scientists have contributed to the widespread belief that carbon should have no place in our energy economies. In The Decarbonization Delusion, Moore argues against this idea, asking us to re-think our assumptions and approach sustainable energy development in a more scientific and dispassionate fashion.

DKK 297.00
1

Decision at Sea - Craig L. Symonds - Bog - Oxford University Press Inc - Plusbog.dk

Decision at Sea - Craig L. Symonds - Bog - Oxford University Press Inc - Plusbog.dk

From thunderous broadsides traded between wooden sailing ships on Lake Erie, to the carrier battles of World War II, to the devastating high-tech action in the Persian Gulf, here is a gripping history of five key battles that defined the evolution of naval warfare--and the course of the American nation. Acclaimed military historian Craig Symonds offers spellbinding narratives of crucial engagements, showing how each battle reveals the transformation of technology and weaponry from one war to the next; how these in turn transformed naval combat; and how each event marked a milestone in American history. BL Oliver Hazard Perry''s heroic victory at Lake Erie, one of the last great battles of the Age of Sail, which secured the Northwestern frontier for the United States BL The brutal Civil War duel between the ironclads Monitor and Virginia, which sounded the death knell for wooden-hulled warships and doomed the Confederacy''s hope of besting the Union navy BL Commodore Dewey''s stunning triumph at Manila Bay in 1898, where the U.S. displayed its "new navy" of steel-hulled ships firing explosive shells and wrested an empire from a fading European power BL The hairsbreadth American victory at Midway, where aircraft carriers launched planes against enemies 200 miles away--and where the tide of World War II turned in the space of a few furious minutes BL Operation Praying Mantis in the Persian Gulf, where computers, ship-fired missiles, and "smart bombs" not only changed the nature of warfare at sea, but also marked a new era, and a new responsibility, for the United States. Symonds records these encounters in detail so vivid that readers can hear the wind in the rigging and feel the pounding of the guns. Yet he places every battle in a wide perspective, revealing their significance to America''s development as it grew from a new Republic on the edge of a threatening frontier to a global superpower. Decision at Sea is a powerful and illuminating look at pivotal moments in the history of the Navy and of the United States. It is also a compelling study of the unchanging demands of leadership at sea, where commanders must make rapid decisions in the heat of battle with lives--and the fate of nations--hanging in the balance.

DKK 191.00
1