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The Microbiome - Richard Lucius - Bog - Springer International Publishing AG - Plusbog.dk

The Microbiome - Richard Lucius - Bog - Springer International Publishing AG - Plusbog.dk

This book unravels in an easily understandable way the exciting molecular connections between our gut microbiome, i.e. the collective microorganisms that we carry in our digestive system, nutrition and the immune system, and how an imbalance can lead to the development of inflammatory diseases. The totality of these gut microorganisms forms a complex ecosystem within us, consisting of hundreds of different species of bacteria. The author, microbiologist Professor Richard Lucius, introduces the historical context of microbiome research, discusses how our lives have changed in recent decades, and explains the composition and function of the microbiome and its connection to the gut and immune system. The book explains in detail and supported with appealing illustrations how allergies, chronic intestinal inflammation, type 1 diabetes, multiple sclerosis, rheumatoid arthritis, psoriasis and coeliac disease develop. Further chapters deal with the effects of nutrition on our intestinal flora and provide tips on building and maintaining a healthy microbiome. An intact bacterial community utilizes food residues that humans cannot digest and in return provides energy and vital substances. Only together with our inhabitants do we form a well-functioning "superorganism". Our immune system, which has developed over millions of years, is calibrated for a meagre, natural life. Under the influence of our modern way of life, the "Western lifestyle", our inner ecosystem is suffering from a loss of species, similar to our external environment. Highly processed foods, the influence of medication, lack of exercise and little contact with environmental bacteria are promoting this erosion process, which in the long term increases the risk of inflammatory diseases and obesity. As a result, more than 25% of people in modern societies suffer from allergies, autoimmune diseases and food intolerances that hardly existed in the past. This development can be counteracted by a healthy lifestyle that strengthens and diversifies the microbiome. This book is aimed at anyone who wants to understand the complex interplay between our gut microbiome, the immune system, nutrition and disease. The English translation of this volume, originally published in German language, was facilitated by artificial intelligence. A language editor has subsequently revised the text further in an endeavor to refine the work stylistically. The content was later revised by the author for accuracy.

DKK 385.00
3

A Study Guide to the ISTQB Foundation Level 2018 Syllabus - Adam Roman - Bog - Springer International Publishing AG - Plusbog.dk

A Study Guide to the ISTQB Foundation Level 2018 Syllabus - Adam Roman - Bog - Springer International Publishing AG - Plusbog.dk

This book is an excellent, helpful and up-to-date resource for all candidates preparing for the ISTQB Foundation Level certification exam based on the new Foundation Level 2018 Syllabus. Although there are plenty of sample questions and information related to the Foundation Level exam on the web, there are two problems with these: Firstly, most of them will soon be outdated, as the old syllabus and exams are going to be retracted in June 2019. Secondly, much of what is available is of poor quality, since many of the sample questions do not follow the strict ISTQB examination rules. This book stands out from other ISTQB-related works through a number of special features: - Topicality: The material complies with the latest version of the Foundation Level syllabus published in 2018. - Quality and originality: The exam questions are original, not redundant, of high quality, fully aligned with the ISTQB exam requirements and have not been published before. - Huge amount of material: It includes 5 full sample exams (200 questions in total) designed in accordance with the ISTQB exam rules, and with the appropriate distribution of questions regarding the learning objectives and K-levels. - Well-thought-out sample questions: The questions not only appropriately cover the corresponding learning objectives (LOs), but also to show the typical pitfalls. - Diversity: The questions from various sample exams related to the same LO are diversified, that is, each of them points out different aspects of a given LO. This is an excellent method for better and more effective learning and preparing for the exam. - Comprehensive, intelligible explanations: All answers are justified and there are detailed and easy-to-understand explanations not only of why a given answer is correct, but also why all the others are wrong. - A lot of bonus material: The book includes a great bonus pack: chapters that explain the white-box and black-box test techniques in a detailed way, a set of exercises on test techniques and the detailed solutions to them, and much more.

DKK 509.00
3

Design Automation Techniques for Approximation Circuits - Daniel Grosse - Bog - Springer International Publishing AG - Plusbog.dk

Nutritional Management of Inflammatory Bowel Diseases - - Bog - Springer International Publishing AG - Plusbog.dk

Simulating Information Retrieval Test Collections - Bodo Billerbeck - Bog - Springer International Publishing AG - Plusbog.dk

Simulating Information Retrieval Test Collections - Bodo Billerbeck - Bog - Springer International Publishing AG - Plusbog.dk

Simulated test collections may find application in situations where real datasets cannot easily be accessed due to confidentiality concerns or practical inconvenience. They can potentially support Information Retrieval (IR) experimentation, tuning, validation, performance prediction, and hardware sizing. Naturally, the accuracy and usefulness of results obtained from a simulation depend upon the fidelity and generality of the models which underpin it. The fidelity of emulation of a real corpus is likely to be limited by the requirement that confidential information in the real corpus should not be able to be extracted from the emulated version. We present a range of methods exploring trade-offs between emulation fidelity and degree of preservation of privacy. We present three different simple types of text generator which work at a micro level: Markov models, neural net models, and substitution ciphers. We also describe macro level methods where we can engineer macro properties of a corpus, giving a range of models for each of the salient properties: document length distribution, word frequency distribution (for independent and non-independent cases), word length and textual representation, and corpus growth. We present results of emulating existing corpora and for scaling up corpora by two orders of magnitude. We show that simulated collections generated with relatively simple methods are suitable for some purposes and can be generated very quickly. Indeed it may sometimes be feasible to embed a simple lightweight corpus generator into an indexer for the purpose of efficiency studies. Naturally, a corpus of artificial text cannot support IR experimentation in the absence of a set of compatible queries. We discuss and experiment with published methods for query generation and query log emulation. We present a proof-of-the-pudding study in which we observe the predictive accuracy of efficiency and effectiveness results obtained on emulated versions of TREC corpora. The study includes three open-source retrieval systems and several TREC datasets. There is a trade-off between confidentiality and prediction accuracy and there are interesting interactions between retrieval systems and datasets. Our tentative conclusion is that there are emulation methods which achieve useful prediction accuracy while providing a level of confidentiality adequate for many applications. Many of the methods described here have been implemented in the open source project SynthaCorpus, accessible at: https://bitbucket.org/davidhawking/synthacorpus/

DKK 509.00
1