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Nucleic Acids and Molecular Biology - Fritz Eckstein - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Nucleic Acids and Molecular Biology - Fritz Eckstein - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Molecular biology is one of the most rapidly developing and at the same time most exciting disciplines. The key to molecular biology lies in the understanding of nucleic acids - their structure, function, and interaction with proteins. Nucleic Acids and Molecular Biology keeps scientists informed of the explosively growing information and complies with the great interest in this field by offering a continued high standard of review. Volume 5 opens with a review of novel DNA-structures found commonly in the telomeres of eukaryotic chromosomes. It turns to the topics of DNA-repair and replication and in-depth studies of DNA-Polymerase I, which leads to the exciting and rapidly moving area of DNA-protein interactions emphasizing aspects of sequence recognition and specificity. A view on the control of gene expression with examples of retroviruses such as HIV or transgenic animals for eukaryotes concludes this volume.

DKK 663.00
1

Medical Decision Making - Thomas Mayrhofer - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Medical Decision Making - Thomas Mayrhofer - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This textbook offers a comprehensive analysis of medical decision-making under uncertainty by combining test information theory with expected utility theory. The authors show how the parameters of Bayes'' theorem can be combined with a value function of health states in order to arrive at informed test and treatment decisions in the face of diagnostic and therapeutic risks. Distinguishing between risk-neutral, risk-averse, and prudent decision-makers, they demonstrate the effects of risk preferences on medical decisions. Furthermore, they analyze individual and multiple tests as well as diagnostic models in which the decision-maker chooses the test outcome. The consequences of test and treatment decisions for the patient are encompassed by quality-adjusted life years (QALYs) and the standard economic model, which applies the willingness to pay for health approach. Lastly, non-expected utility models of choice under risk and uncertainty are presented. Although these models can explain some of the test and treatment decisions observed, they are less suitable for normative analyses aimed at providing guidance on medical decision-making. This third edition provides extensively revised versions of all chapters and reflects recent innovations in medical decision-making such as decision curve analysis. New chapters focus on the health economics of and revealed preferences in medical decisions. The book is intended for students of (health) economics and medicine as well as for medical decision-makers and physicians dealing with uncertainty in their test and treatment decisions.

DKK 476.00
1

Selenium WebDriver Recipes in C# - Courtney Zhan - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Selenium WebDriver Recipes in C# - Courtney Zhan - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Solve your Selenium WebDriver problems with this quick guide to automated testing of web applications with Selenium WebDriver in C#. This third edition contains hundreds of solutions to real-world problems, with clear explanations and ready-to-run Selenium test scripts that you can use in your own projects. Updated to Selenium version 4, this revision includes Visual Studio Code set up, additional recipes, and new chapters on Selenium DevTools and continuous testing. You'll see how to use Selenium WebDriver for select lists, navigation, assertions, frames, file upload and pop-up dialogs. You'll also learn how to locate web elements and test functions for hyperlinks, buttons, TextFields and TextAreas, radio buttons, CheckBoxes, and more. What You'll Learn Debug test scripts and test data Work with Selenium Remote Control Server Manage and deal with browser profiles and capabilitiesMonitor tests for advanced user interactions and experiences (UX)Who This Book Is For Experienced .NET and C# Windows application programmers/developers.

DKK 434.00
1

Hypersonic Flows for Reentry Problems - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Hypersonic Flows for Reentry Problems - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This entry describes the experimental work conducted in the Department of Aeronautics at Imperial College in connection with Test Problems 1 and 2 of the "Workshop on Hypersonic Flows for Reentry Problems, Part I". These are defined as follows: Test Problem 1 Flow Over a Slender Cone Test Problem 2 Turbulent Base Flow The main requirement of this text is to present the experimental data for direct comparison with the predictions of CFD codes. We have therefore concentrated mainly on a factual statement of measuring techniques and results, together with an assessment of experimental accuracy. Future publications will be devoted to more extensive physical interpretations and discussions of the results. We have produced a large volume of data, some of which were categorised as "MANDATORY" and some as "OPTIONAL" for the purposes of CFD validation. However, only the "MANDATORY" data are presented here, although the other data are available and will be published separately later. 2. EXPERIMENTAL ARRANGEMENT 2. 1 The Test Facility The experiments were conducted in the Imperial College No. 2 Gun tunnel. This facility is a conventional intermittent blowdown tunnel with a contoured Mach 9 (nominal) axisymmetric nozzle fed by a free piston compression heater. The operating condition under which the data contained in this report were obtained is presented in Table 1. Test 2 T (oK) M b. Mlm Po (N/m ) Re/m T (oK) IX) IX) Case IX) w 1. 1 7 7 +0. 14 9. 16 6. 67x10 5. 5xl0 59.

DKK 663.00
1

Testing the Creditcoin Blockchain - Alexander Todorov - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Testing the Creditcoin Blockchain - Alexander Todorov - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Follow the quality engineering journey of the Creditcoin blockchain across four distinct implementation versions and a myriad of technologies. Through the eyes of a test engineer, this book discusses testing implementations with the Hyperledger Sawtooth and Substrate frameworks, testing switch from proof-of-work to proof-of-stake consensus algorithm, and testing an Ethereum Virtual Machine compatibility layer. You’ll traverse several years of fast-paced multiple blockchain implementations and technological changes including an explanation of all major components involved, and the approach taken. You’ll also look at examples of test automation approaches and tools, interesting bugs, and testing challenges. Most everything discussed in Testing the Creditcoin Blockchain is open source, ensuring easy access, and multiple references to source code and GitHub are included throughout. Who This Book Is ForSoftware testers and quality engineers with limited experience working on a blockchain implementation. What You Will LearnStudy the many of the components of a distributed blockchain network. See how components work and where testing can be plugged into a distributed blockchain network environment. Glimpse into the daily blockchain testing activities of a principal test engineer. Become familiar with a fast-paced technical software development project.

DKK 519.00
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Permutation Testing for Isotonic Inference on Association Studies in Genetics - Livio Corain - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co.

Permutation Testing for Isotonic Inference on Association Studies in Genetics - Livio Corain - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co.

The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. In this framework we will work out some nonparametric statistical permutation tests and likelihood-based tests to perform case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies, where we deal with several genes and several alleles together. Furthermore, we show simulations under different assumptions on the genetic model and analyse real data sets by simply studying one locus with the permutation test.

DKK 434.00
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Software Testing for Managers - Ross Radford - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Software Testing for Managers - Ross Radford - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Software leaders, directors, and managers of all types need to know about software testing. It can be a tough climb up the mountain of technical jargon. Engineers seem to be speaking a language all their own sometimes. Most books on testing are deep in the weeds with technical terms and techniques that simply aren’t applicable even to technical managers. This book provides a high-level perspective on broad topics in a friendly, easy-to-absorb style. Get started and up to speed quickly with immediately useful, actionable guidance. Guidance on team structure, best practices and even common pitfalls will save you time and money, while automation and code reuse will provide exponential value. There’s a gap of knowledge between engineers and their managers; they are almost speaking different languages and the jargon can be confusing. There’s a lot to know about the world of testing. Test from the Top delivers quick, concise guidance to bridge the gap! It offers clear, actionable steps and is a must have for busy leaders who need quick answers. What You Will Learn:How and where to integrate testing in the software development lifecycleTesting terminology and concepts from a management perspectiveCommon pitfalls of testing, how to avoid wasted timeHow to hire test-aware teamsThe value in reusing test code for more generalized automationWho This Book is for:Software managers, Lead Software Engineers, Tech Directors, CTOs, Project Managers, software leaders of all kinds. These leaders understand the value of testing, but have not yet built out extensive automation or team structure. Either new to testing concepts or modernizing systems or looking to improve software quality. Assumed to have a working knowledge of the Software Development Lifecycle and basic project management (no specific methodology required).

DKK 476.00
1

Process Innovation: Enabling Change by Technology - Daniel R. A. Schallmo - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Process Innovation: Enabling Change by Technology - Daniel R. A. Schallmo - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This management manual and textbook introduces the theoretical basics of process management and provides a procedural model for process innovation. The procedural model makes it possible to develop customer-oriented processes in a structured manner and to design them in order to meet changing requirements. This textbook has been recommended and developed for university courses in Germany, Austria and Switzerland. This book enables readers to understand and apply the seven phase procedural model for process innovation in order to design and implement innovative processes. Exercises and review questions test understanding of the theoretically acquired knowledge.

DKK 349.00
1

Transactions on Large-Scale Data- and Knowledge-Centered Systems LI - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Transactions on Large-Scale Data- and Knowledge-Centered Systems LI - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

The LNCS journal Transactions on Large-Scale Data and Knowledge-Centered Systems focuses on data management, knowledge discovery, and knowledge processing, which are core and hot topics in computer science. Since the 1990s, the Internet has become the main driving force behind application development in all domains. An increase in the demand for resource sharing (e.g., computing resources, services, metadata, data sources) across different sites connected through networks has led to an evolution of data- and knowledge-management systems from centralized systems to decentralized systems enabling large-scale distributed applications providing high scalability. This, the 51st issue of Transactions on Large-Scale Data and Knowledge-Centered Systems, contains five fully revised selected regular papers. Topics covered include data anonyomaly detection, schema generation, optimizing data coverage, and digital preservation with synthetic DNA.

DKK 426.00
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The Music of the Big Bang - Amedeo Balbi - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

The Music of the Big Bang - Amedeo Balbi - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Ever since its infancy, humankind has been seeking answers to some very basic and profound questions. Did the Universe begin? If it did, how old is it, and where did it come from? What is its shape? What is it made of? Fascinating myths and brilliant in- itions attempting to solve such enigmas can be found all through the history of human thought. Every culture has its own legends, itsownworldcreationtales,itsphilosophicalspeculations,itsre- gious beliefs. Modern science, however, cannot content itself with fanciful explanations, no matter how suggestive they are. No- days, our theories about the Universe, built upon rational ded- tion, have to survive the hard test of experiment and observation. Cosmology, the science which studies the origin and evo- tion of the Universe, had to overcome enormous dif?culties before it could achieve the same level of dignity as other physical dis- plines. At ?rst, it had no serious physical model and mathematical tools that could be used to address the complexity of the problems it had to face. Then, it suffered from a chronic lack of experim- tal data, which made it almost impossible to test the theoretical speculations. Given this situation, answering rigorously the many questions on the nature of the Universe seemed nothing more than a delusion. Today, however, things have changed. We live in the golden age of cosmology: an exciting moment, when, for the ?rst time, we are able to scienti?cally understand our Universe.

DKK 310.00
1

Analysis of Nucleic Acids by Capillary Electrophoresis - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Analysis of Nucleic Acids by Capillary Electrophoresis - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Die Kapillarelektrophorese (CE) ist heute in biochemischen Laboratorien noch nicht als Routinemethode zur DNA-Trennung etabliert, obwohl sie diverse Vorzüge gegenüber den derzeitigen Methoden besitzt. In diesem Band stellen verschiedene Wissenschaftler die theoretischen Aspekte der Trennung von Oligonucleinsäuren mit der CE, die instrumentellen Grundlagen und deren Grenzen und schließlich die praktische Anwendung in der Biochemie und Molekularbiologie vor. This book on capillary electrophoresis is unique in its focus on the separation of nucleic acids. The importance of electrophoretic separation in every molecular biology laboratory justifies this specialization, which is also reflected in the development of instrumentation. This book is aimed to help to implement this rather new and promising technology in the biological laboratories and to help to overcome typical problems that can occur when starting with a new technique. It should also trigger further development in the field. It covers the theoretical background as well as practical examples of usual applications. The authors are all experts in their field, having many years of experience with capillary electrophoresis and their application to nucleic acids.

DKK 816.00
1

Molecular Radio-Oncology - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Molecular Radio-Oncology - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.

DKK 689.00
1

Chemistry of Renewables - Thomas Seidensticker - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Chemistry of Renewables - Thomas Seidensticker - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This textbook introduces the industrial production and processing of natural resources. It is divided into six major topics (fats and oils, carbohydrates, lignin, terpenoids, other natural products, biorefinery), which are divided into a total of 20 chapters. Each chapter is self-contained and therefore a compact learning unit, which can be worked on by students in self-study or presented by lecturers. Clear illustrations, flow diagrams, apparatus drawings and photos facilitate the understanding of the subject matter. All chapters end with a succinct summary, the "Take Home Messages". Each chapter is supplemented by ten short test questions, which can be solved quickly after working through the chapter; the answers are at the end of the book. All chapters contain bibliographical references that focus on essential textbooks and reference works. As a prior knowledge, only basic knowledge of chemistry is required.

DKK 519.00
1

Patch Testing Tips - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Patch Testing Tips - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This book is a compendium of tips on many different aspects of patch testing based on the recommendations of the International Contact Dermatitis Research Group (ICDRG), which is the reference group for all dermato-allergologists. It is intended to complement the book Patch Testing and Prick Testing: A Practical Guide by J.-M. Lachapelle and H. Maibach, which is an official publication of the ICDRG now in its third edition. Among the wide variety of topics covered are pitfalls, legal aspects, patch testing with ultrasonic bath extracts, the role of patch testing in occupational contact dermatitis and atopic dermatitis, semi-open tests, the implications of a negative test, patch testing validity, selection of extra allergens and patch testing in the tropics. Many illustrations are included and all information is completely up-to-date. This book will be of value to all practicing dermatologists.

DKK 536.00
1

Cell and Molecular Biology for Non-Biologists - Lorenz Adlung - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Cell and Molecular Biology for Non-Biologists - Lorenz Adlung - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This book introduces the basics of cellular and molecular biology on a basic level including detailed explanations and examples. It lays the foundation for a systematic understanding of biology, which is essential in order to handle big data in biomedical research. Comprehension of what is measured, how it is measured and how to interpret results is a precondition for the development of novel therapies against diseases. Interdisciplinary research benefits from versatile approaches to generate and test hypotheses, which may lead to new discoveries. Therefore, it requires a new generation of biologists from diverse backgrounds - and they need this introduction. This book helps students and experts from e.g. computer science, informatics, mathematics, physics, and related fields or even if you are in sales and marketing and want to have a better understanding of the biology behind certain products.

DKK 604.00
1

An Invitation to Mathematics - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

An Invitation to Mathematics - - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

This Invitation to Mathematics consists of 14 contributions, many from the world''s leading mathematicians, which introduce the readers to exciting aspects of current mathematical research. The contributions are as varied as the personalities of active mathematicians, but together they show mathematics as a rich and lively field of research. The contributions are written for interested students at the age of transition between high school and university who know high school mathematics and perhaps competition mathematics and who want to find out what current research mathematics is about. We hope that it will also be of interest to teachers or more advanced mathematicians who would like to learn about exciting aspects of mathematics outside of their own work or specialization. Together with a team of young ``test readers'''', editors and authors have taken great care, through a substantial ``active editing'''' process, to make the contributions understandable by the intended readership.

DKK 385.00
1

Closed Functional Treatment of Fractures - Loren Latta - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Closed Functional Treatment of Fractures - Loren Latta - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

The purpose of this book is to report on my 17 years of experience in the development and implementation of a closed functional method of treatment of certain fractures of long bones of the appendicular skeleton. My personal experiences, clinical results, and the basic concepts underlying the treatment philosophy are reported. Illustrations demonstrating the techniques of application of functional casts and braces are presented in detail as well as a step-by-step description of the management regime and a discussion of the behavior of fractures under this system. Indications and contraindications for the use of this method of treatment are clearly outlined. I consider it important to compile this information for I believe that the system has withstood the test of time and is sufficiently sound to be incorporated in the armamentarium of the orthopaedic surgeon. Also, it may have a favorable socioeconomic impact since it offers a viable alternative in the treatment of frac­ tures.

DKK 663.00
1

Learning VMware Workstation Pro for Windows: Volume 2 - Peter Von Oven - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Learning VMware Workstation Pro for Windows: Volume 2 - Peter Von Oven - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

VMware Workstation is a software solution that provides a type-2 hypervisor, or desktop hypervisor, that runs on x64 Windows and Linux-based operating systems. It enables users to create and run virtual machines, containers, and Kubernetes clusters simultaneously on their physical devices without having to reformat or dual-boot the underlying device. There are several use cases for VMware Workstation. For IT pros, it allows them to test applications andoperating system builds, as well as enable remote control of vSphere datacenter infrastructure. Developers can run multiple different operating systems or different versions of operating systems on a single device giving them the platform flexibility to test, develop, and troubleshoot applications cost-effectively. Finally, for the greater workforce, VMware Workstation can enable BYOD device initiatives allowing employees to run a full corporate environment on their device without deleting or reformatting it. Learning VMware Workstation Pro for Windows – Part 2 provides the reader with a practical, step-by-step guide to creating and managing virtual machines using VMware Workstation, starting with an overview of hypervisors and desktop hypervisors. Next, it talks about each resource, such as CPU, memory, and networking, and how these are configured in a virtual environment. After that, it demonstrates the installation of VMware Workstation, configuration, and then building and managing different virtual machines running on different operating systems such as ChromeOS, and Linux, and building an ESXi lab environment. Towards the end, readers will learn how to use command line tools, such as the REST API, and vmrun, before going on to discuss upgrading and troubleshooting your VMware Workstation environment. By the end of this book, readers will have full knowledge of VMware Workstation Pro. This book is a continuation of " Learning VMware Workstation Pro for Windows – Part 1 " where readers learn how to build and manage different virtual machines running on different operating systems and build an ESXi lab environment with VMware Workstation. You Will:Learn how to run containers on a VMware workstationUnderstand how to use the command line to configure and control Workstation Pro and virtual machinesPractice the use of REST API for Workstation Pro This book is for: Developers, IT professionals, VMware certified professionals both remote and Bring your device (BYOD).

DKK 519.00
1

Flame Game Development - Andres Cruz Yoris - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Flame Game Development - Andres Cruz Yoris - Bog - Springer-Verlag Berlin and Heidelberg GmbH & Co. KG - Plusbog.dk

Reimagine your development process and create, test, and deploy your mobile, web, desktop, and embedded apps from a single codebase. This book shows you how to leverage Flame, the modular Flutter game engine, to build cross-platform 2D games. With Flutter, you can create all kinds of apps by making subtle changes to projects at the code level. Guided by a practical project-based approach, you'll begin by downloading and installing the game engine. You'll then move on to creating widgets in Flutter and components within our game, such as player, enemy, background, consumables, etc. The book also shows you how to add sprites, render images, setup animation, and much more. Flame Game Development is perfect for the novice eager to gain hands-on knowledge of this exciting game engine's library to create a simple 2D game. What You'll LearnApply Flutter coding skills to game developmentDevelopgames that can be played on all platformsCreate your first 2D game using FlameWho This Book Is ForBeginners who want to learn how to develop games on Flame and create their first 2D game with Flutter.

DKK 476.00
1