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Nuclear Test Ban - Hein Haak - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear Test Ban - Hein Haak - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear tests have caused public concern ever since the first such test was conducted, more than six decades ago. During the Cold War, however, con- tions were not conducive to discussing a complete ban on nuclear testing. It was not until 1993 that negotiations on such a treaty finally got under way. From then on, things moved relatively quickly: in 1996, the United Nations General Assembly adopted the Comprehensive Nuclear-Test-Ban Treaty (CTBT). To date, the Treaty has been signed by 178 states and ratified by 144, though it has yet to enter into force, as nine out of 44 ‘‘Annex 2 states’’, whose ratification is mandatory, have not heeded the call. Nevertheless, the CTBT verification system is already provisionally operational and has proven its effectiveness. We commend the CTBT organisation in Vienna for its successful efforts to build a verification network. This book is an excellent overview of the evolution of the CTBT and its verification regime. The authors are eminent scholars from the Netherlands, Norway and Sweden who have been intimately involved with the CTBT and its verification agency, the CTBTO Preparatory Commission, from their inc- tion to the present day. They have written a thorough and engaging narrative of the long road that led to the CTBT. Their story will appeal to both the layman and the expert and provide useful lessons for future negotiations on disarmament issues.

DKK 689.00
1

Study Skills and Test-Taking Strategies for Medical Students - Deborah D. Shain - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear Cardiology Study Guide - Andrzej Moniuszko - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear Medicine Technology Study Guide - Andrzej Moniuszko - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Invariant Natural Killer T-Cells - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Looking Back - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

PET and PET/CT Study Guide - Andrzej Moniuszko - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Emergence of Culture - Philip Chase - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Energiya-Buran - Bart Hendrickx - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Sensory Evaluation of Food - Hildegarde Heymann - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Induced Mutagenesis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Induced Mutagenesis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results. Chris Lawrence v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this Conference by the U.,S. Department of Energy, The Foundation for Microbiology, Exxon Corporation and the University of Rochester.

DKK 434.00
1

Single-Cell Mutation Monitoring Systems - Aftab A. Ansari - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Single-Cell Mutation Monitoring Systems - Aftab A. Ansari - Bog - Springer-Verlag New York Inc. - Plusbog.dk

There is general agreement that increased environmental pollution poses a potential health hazard to humans and that effective control of such genetic injury requires monitoring the exposed individuals for genetic damage and identifying chemicals that may cause mutation or cancer. Tests available for identifying mutagens or carcinogens range from relatively simple, rapid assays in prokaryotes and test systems utilizing mammalian cells in tissue culture to highly elaborate tests in intact animals. No single test can provide data for an unequivocal assessment of the mutagenicity of a given chemical and the risk it might pose to human health. A tier approach, therefore, was suggested for mutagenicity testing in which the suspected agents would be initially evaluated with simple, inexpensive tests that would give qualitative results. Chemicals found to be positive in the first-tier testing would then be evaluated with more complex tests, including those based on mammalian cells in culture. Testing in the final tier requires whole-animal studies, and is expensive and time-consum­ ing, and even the results from these studies need to be extrapolated for human risk assessment. The mutation systems based on whole animals require scoring large num­ bers of animals, and therefore are not practical for the routine testing of muta­ gens. As an alternative to monitoring the pedigree, cells from exposed individ­ uals may be considered for screening for point mutations through the use of an appropriate marker protein.

DKK 434.00
1

Logic Synthesis Using Synopsys - Taher Abbasi - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Logic Synthesis Using Synopsys - Taher Abbasi - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Logic synthesis has become a fundamental component of the ASIC design flow, and Logic Synthesis Using Synopsys ® has been written for all those who dislike reading manuals but who still like to learn logic synthesis as practised in the real world. The primary focus of the book is Synopsys Design Compiler®: the leading synthesis tool in the EDA marketplace. The book is specially organized to assist designers accustomed to schematic capture based design to develop the required expertise to effectively use the Compiler. Over 100 `classic scenarios'' faced by designers using the Design Compiler have been captured and discussed, and solutions provided. The scenarios are based both on personal experiences and actual user queries. A general understanding of the problem-solving techniques provided will help the reader debug similar and more complicated problems. Furthermore, several examples and dc - shell scripts are provided. Specifically, Logic Synthesis Using Synopsys ® will help the reader develop a better understanding of the synthesis design flow, optimization strategies using the Design Compiler, test insertion using the Test Compiler®, commonly used interface formats such as EDIF and SDF, and design re-use in a synthesis-based design methodology. Examples have been provided in both VHDL and Verilog. Audience: Written with CAD engineers in mind to enable them to formulate an effective synthesis-based ASIC design methodology. Will also assist design teams to better incorporate and effectively integrate synthesis with their existing in-house design methodology and CAD tools.

DKK 663.00
1

The Reticuloendothelial System - Sherwood M. Reichard - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The Reticuloendothelial System - Sherwood M. Reichard - Bog - Springer-Verlag New York Inc. - Plusbog.dk

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio­ medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular sys­ tem. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con­ cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as well as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that by presenting information concerning these apparently het­ erogeneous topics under the unifying umbrella of the RES attention will be focused on the similarities as well as interactions among the cell types constitut­ ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol­ umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloen­ dothelial Societies.

DKK 663.00
1

Selecting the Mercury Seven - Colin Burgess - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Selecting the Mercury Seven - Colin Burgess - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The names of the seven Mercury astronauts were announced in April 1959 amid a flurry of publicity and patriotism. This work provides biographical details of all thirty-two finalists for the seven coveted places as America''s pioneering astronauts. All of the candidates were among the nation''s elite pilots involved in testing new supersonic aircraft capabilities. Most had served as wartime fighter and bomber pilots; some were test pilots on top secret and sophisticated aviation projects, while others were fleet admirals, prisoners of war, and proposed pilots for spaceflight programs such as the Dyna-Soar (X-20). The names of all 32 finalists have been kept secret until very recently. "Selecting the Mercury Seven" also relates the history and difficulties behind the initial choice of candidates. The lives, motivations, military careers, and achievements of the unsuccessful twenty-five finalists are explored first in fully authorized biographies. Test pilots for the U.S. Navy, Air Force, and Marine Corps, each man has a fascinating and very different story to tell. All thirty-two men had to endure meticulous, demeaning, and brutal week-long medical examinations at the Lovelace Clinic in New Mexico. This was followed by another torturous week at the Wright Aeromedical Laboratory in Ohio, where they were subjected to extreme fitness and physiological testing, the sole purpose of which was to sort out the Supermen from the near-supermen. The final part of the book examines the accomplishments and spaceflights of the seven successful candidates, bringing their amazing stories right up to date.

DKK 493.00
1

Food Allergens - Marija Gavrovic Jankulovic - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Food Allergens - Marija Gavrovic Jankulovic - Bog - Springer-Verlag New York Inc. - Plusbog.dk

A food allergen has the ability to first elicit an IgE response, and then, on subsequent exposures, a clinical response to the same or similar protein. How harmless food protein becomes recognized by the mucosal immune system as an allergen remains an open question and more data are needed to explain how regulatory mechanisms of the mucosal immune system fail and result in allergic sensitization to dietary antigens. Some biochemical characteristics associated with food allergens, such as the presence of multiple, linear IgE-binding epitopes and the resistance of the protein to digestion and processing, seem to predominate among food allergens. Digestion susceptibility of food allergens that sensitize via the gastrointestinal tract and stability to food processing conditions are inherently related to protein structural features. Thereby, physiological changes in the digestion process, pathological conditions affecting digestion, as well as procedures and food processing conditions that affect protein structure may all have a profound effect on the sensitizing potential and allergenicity of food proteins. In addition, signals coming from the diet and micro biome can modulate regulatory mechanisms of the mucosal immune system and influence mucosal immunity and intestinal barrier function. The detection of allergenic ingredients in food products has received increased attention from the food industry and legislative and regulatory agencies over recent years. This has resulted in the improvement of applied safety measures that provide protection for food-allergic consumers and development of sensitive and highly specific analytical methods of food allergens detection. Food allergy is an important and common health issue and therefore there is a need to characterize the sensitizing potential of newly introduced proteins in genetically engineered foods. A combination of in vitro and in silico methods provide information that contributes to safety assessment. Suitable in vivo models may provide a more holistic assessment of allergenic potential of novel food proteins.

DKK 780.00
1

Evidence-Based Neuroimaging Diagnosis and Treatment - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

SystemVerilog for Verification - Greg Tumbush - Bog - Springer-Verlag New York Inc. - Plusbog.dk

SystemVerilog for Verification - Greg Tumbush - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Based on the highly successful second edition, this extended edition of SystemVerilog for Verification: A Guide to Learning the Testbench Language Features teaches all verification features of the SystemVerilog language, providing hundreds of examples to clearly explain the concepts and basic fundamentals. It contains materials for both the full-time verification engineer and the student learning this valuable skill. In the third edition, authors Chris Spear and Greg Tumbush start with how to verify a design, and then use that context to demonstrate the language features, including the advantages and disadvantages of different styles, allowing readers to choose between alternatives. This textbook contains end-of-chapter exercises designed to enhance students'' understanding of the material. Other features of this revision include: - New sections on static variables, print specifiers, and DPI from the 2009 IEEE language standard - Descriptions of UVM features such as factories, the test registry, and the configuration database - Expanded code samples and explanations - Numerous samples that have been tested on the major SystemVerilog simulators SystemVerilog for Verification: A Guide to Learning the Testbench Language Features, Third Edition is suitable for use in a one-semester SystemVerilog course on SystemVerilog at the undergraduate or graduate level. Many of the improvements to this new edition were compiled through feedback provided from hundreds of readers.

DKK 842.00
1

Manual of Lower Gastrointestinal Surgery - Claude E. Welch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Manual of Lower Gastrointestinal Surgery - Claude E. Welch - Bog - Springer-Verlag New York Inc. - Plusbog.dk

The surgeon who desires an atlas of techniques covering operations on the colon and rectum almost surely prefers a concise volume rather than an encyclopedic compilation of the innumerable procedures that have been described in the literature. This book includes the operations that have proved to be useful and have survived the test of time. They now are in general use in the Massachusetts General Hospital. Space limitations have necessitated exclusion of detailed illustrations of a number of infrequently performed procedures, such as pelvic exenter­ ation for cancer of the rectum. In such instances bibliographic references have been provided for ready reference. The bibliography emphasizes recent contributions because they are easily available to the reader. Critical comments by the authors concerning certain technical pro­ cedures may be due to personal bias and certainly do not imply that the alternative methods are undesirable. Furthermore, the brevity of discus­ sion of anatomy, physiology, and pathology and the neglect of details of medical therapy of numerous colorectal diseases must be attributed to the fact that this volume is directed primarily toward the practicing surgeon. Thanks are due to the artists Mrs. Edith Tagrin and Mr. Robert Galla, and to Miss Evelyn Hall for help in the preparation of the manuscript. Claude E. Welch, M.D. Leslie W. Ottinger, M.D. John P. Welch, M.D. .

DKK 663.00
1