64 resultater (0,31290 sekunder)

Mærke

Butik

Pris (EUR)

Nulstil filter

Produkter
Fra
Butikker

The Sensory Evaluation of Dairy Products - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear Test Ban - Hein Haak - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear Test Ban - Hein Haak - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Nuclear tests have caused public concern ever since the first such test was conducted, more than six decades ago. During the Cold War, however, con- tions were not conducive to discussing a complete ban on nuclear testing. It was not until 1993 that negotiations on such a treaty finally got under way. From then on, things moved relatively quickly: in 1996, the United Nations General Assembly adopted the Comprehensive Nuclear-Test-Ban Treaty (CTBT). To date, the Treaty has been signed by 178 states and ratified by 144, though it has yet to enter into force, as nine out of 44 ‘‘Annex 2 states’’, whose ratification is mandatory, have not heeded the call. Nevertheless, the CTBT verification system is already provisionally operational and has proven its effectiveness. We commend the CTBT organisation in Vienna for its successful efforts to build a verification network. This book is an excellent overview of the evolution of the CTBT and its verification regime. The authors are eminent scholars from the Netherlands, Norway and Sweden who have been intimately involved with the CTBT and its verification agency, the CTBTO Preparatory Commission, from their inc- tion to the present day. They have written a thorough and engaging narrative of the long road that led to the CTBT. Their story will appeal to both the layman and the expert and provide useful lessons for future negotiations on disarmament issues.

DKK 689.00
1

Study Skills and Test-Taking Strategies for Medical Students - Deborah D. Shain - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Induced Mutagenesis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Induced Mutagenesis - - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results. Chris Lawrence v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this Conference by the U.,S. Department of Energy, The Foundation for Microbiology, Exxon Corporation and the University of Rochester.

DKK 434.00
3

Single-Cell Mutation Monitoring Systems - Aftab A. Ansari - Bog - Springer-Verlag New York Inc. - Plusbog.dk

Single-Cell Mutation Monitoring Systems - Aftab A. Ansari - Bog - Springer-Verlag New York Inc. - Plusbog.dk

There is general agreement that increased environmental pollution poses a potential health hazard to humans and that effective control of such genetic injury requires monitoring the exposed individuals for genetic damage and identifying chemicals that may cause mutation or cancer. Tests available for identifying mutagens or carcinogens range from relatively simple, rapid assays in prokaryotes and test systems utilizing mammalian cells in tissue culture to highly elaborate tests in intact animals. No single test can provide data for an unequivocal assessment of the mutagenicity of a given chemical and the risk it might pose to human health. A tier approach, therefore, was suggested for mutagenicity testing in which the suspected agents would be initially evaluated with simple, inexpensive tests that would give qualitative results. Chemicals found to be positive in the first-tier testing would then be evaluated with more complex tests, including those based on mammalian cells in culture. Testing in the final tier requires whole-animal studies, and is expensive and time-consum­ ing, and even the results from these studies need to be extrapolated for human risk assessment. The mutation systems based on whole animals require scoring large num­ bers of animals, and therefore are not practical for the routine testing of muta­ gens. As an alternative to monitoring the pedigree, cells from exposed individ­ uals may be considered for screening for point mutations through the use of an appropriate marker protein.

DKK 434.00
3