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Forensic DNA Evidence Interpretation - - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Evidence Interpretation - - Bog - Taylor & Francis Ltd - Plusbog.dk

Now in its second edition, Forensic DNA Evidence Interpretation is the most comprehensive resource for DNA casework available today. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. The book begins by reviewing all pertinent biology, and then provides information on every aspect of DNA analysis. This includes modern interpretation methods and contemporary population genetic models available for estimating DNA frequencies or likelihood ratios. Following a chapter on procedures for validating databases, the text presents overviews and performance assessments of both modern sampling uncertainty methods and current paternity testing techniques, including new guidelines on paternity testing in alignment with the International Society for Forensic Genetics. Later chapters discuss the latest methods for mixture analysis, LCN (ultra trace) analysis and non-autosomal (mito, X, and Y) DNA analysis. The text concludes with an overview of procedures for disaster victim identification and information on DNA intelligence databases. Highlights of the second edition include: - New information about PCR processes, heterozygote balance and back and forward stuttering - New information on the interpretation of low template DNA, drop models and continuous models - Additional coverage of lineage marker subpopulation effects, mixtures and combinations with autosomal markers This authoritative book provides a link among the biological, forensic, and interpretative domains of the DNA profiling field. It continues to serve as an invaluable resource that allows forensic scientists, technicians, molecular biologists and attorneys to use forensic DNA evidence to its greatest potential.

DKK 835.00
1

Forensic DNA Transfer - Jane Moira Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Transfer - Jane Moira Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Transfer provides a guide to the recognition and current understanding of DNA transfer in forensic criminal investigations. Increased improvements in technology mean that it is now routinely possible to obtain DNA profiles from non-visible deposits. How or when the DNA in question was deposited may be an issue in the context of the case, especially if the donor of the DNA is not in dispute. A DNA profile alone cannot reveal when or how that DNA was deposited at a crime scene, nor can it reveal the body matter from which it originated. Issues of transfer associated with activities may be debated—which the traditional discrimination purpose of DNA profiling cannot address. DNA may be everywhere and anywhere—in homes, at workplaces, during transport, and on personal items including clothing. DNA from a person may be on an object they have never contacted or in a room they have never entered. Concepts discussed in the book include non-self DNA on hands through day-to-day activities, the prevalence of background DNA in the environment and perhaps on the exhibit, the persistence of any DNA transferred, and that a DNA result will depend on these variables as well as recovery techniques. Since DNA may be transferred to an exhibit: (a) during the commission of a crime, (b) before the crime, and/or (c) after the crime through handling, examination, and testing, this book covers various transfer pathways and sources of DNA. Documented cases of inadvertent transfer of DNA resulting in wrongful convictions or the misdirection of criminal investigations are discussed—with an emphasis on contamination mitigation throughout the entire process. Forensic DNA Transfer examines the additional complexity resulting from non-visible deposits of DNA that impact on sampling and testing regimes. The changing understanding of the composition of purported ''touch DNA'' deposits from the skin, including extracellular DNA transported via body secretions, is described. Further, the newer focus on interpreting DNA evidence—using activity level propositions and the rationale and associated issues—is also discussed.

DKK 542.00
1

Forensic DNA Analysis - - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Analysis - - Bog - Taylor & Francis Ltd - Plusbog.dk

The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing, forensic casework, family lineage studies, identification of human remains, and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize, document, collect, and store it. The remaining chapters examine: - - The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remains - Studies carried out on the use of both messenger RNA and small (micro) RNA profiling - Real-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotyping - Capillary electrophoresis (CE) as a tool for forensic DNA analysis - Next-generation short tandem repeat (STR) genotyping kits for forensic applications, the biological nature of STR loci, and Y-chromosome STRs (Y-STRs) - Mitochondrial DNA (mtDNA) sequence analysis - Single nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in typing highly degraded DNA - Deep-sequencing technologies - The current state of integrated systems in forensic DNA analysis - The book concludes by discussing various aspects of sample-processing training and the entities that provide such training programs. This volume is an essential resource for students, researchers, teaching faculties, and other professionals interested in human identification/forensic DNA analysis.

DKK 835.00
1

Forensic DNA Applications - - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Applications - - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Applications: An Interdisciplinary Perspective, Second Edition is fully updated to outline the latest advances in forensic DNA testing techniques and applications. It continues to fill the need for a reference book for people working in the field of forensic molecular biology testing and research as well as individuals investigating and adjudicating cases involving DNA evidence, whether they be civil or criminal cases. DNA techniques have greatly impacted obvious traditional forensic areas, but such advances have also positively affected myriad new areas of research and inquiry. It is possible today to think about solving forensic problems that were simply unheard of even a few years ago. As such, the book pulls all relevant research and applied science together into a detailed and comprehensive collection. Part I begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. Part II moves on to cover the various uses and applications of analyzing collected physical evidence, victim identification in mass disasters, analyzing animal DNA, forensic botany, and other unique applications. Part III is dedicated to the latest advances and developments in human molecular biology and Part IV looks at policies and laws and ethics governing DNA evidence, and its utilization in various cases and the courts. Forensic DNA Applications, Second Edition covers cutting-edge research and advancements in the field and is the most up-to-date reference available. Edited and contributed to by the world''s foremost leaders in the field, it is a must-have reference for established professionals, and an essential resource to legal professionals—lawyers and judges dealing with civil and criminal cases involving DNA technology—as well as students entering the fields of genetics and forensic DNA analysis.

DKK 646.00
1

Dogs in the North - - Bog - Taylor & Francis Ltd - Plusbog.dk

Dogs in the North - - Bog - Taylor & Francis Ltd - Plusbog.dk

Dogs in the North offers an interdisciplinary in-depth consideration of the multiple roles that dogs have played in the North. Spanning the deep history of humans and dogs in the North, the volume examines a variety of contexts in North America and Eurasia. The case studies build on archaeological, ethnohistorical, ethnographic, and anthropological research to illuminate the diversity and similarities in canine–human relationships across this vast region. The book sheds additional light on how dogs figure in the story of domestication, and how they have participated in partnerships with people across time. With contributions from a wide selection of authors, Dogs in the North is aimed at students and scholars of anthropology, archaeology, and history, as well as all those with interests in human–animal studies and northern societies.

DKK 457.00
1

Artificial DNA - - Bog - Taylor & Francis Ltd - Plusbog.dk

Artificial DNA - - Bog - Taylor & Francis Ltd - Plusbog.dk

Combining elements of biochemistry, molecular biology, and immunology, artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis, hybridization, amplification, protein engineering, anti-sense technology, DNA vaccines, protein vaccines, recombinant antibodies, screening for genetic and pathogenic diseases, development of materials with new biochemical and structural properties, and many more. Artificial DNA: Methods and Applications introduces the concept of artificial DNA that has been rationally designed and explains how it may be exploited in order to develop products that will achieve your intended purpose. The first part of the book covers methods of oligonucleotide synthesis and direct applications of synthetic DNA. The second part describes methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. The authors also discuss the different trends and future developments within each application area . With state-of-the art research, the contributing authors describe how to engineer proteins using rational and semi-rational design to exhibit the desired traits and detail the various amplification reactions and hybridization techniques for modeling evolution and for use in basic research. The only text devoted to this subject, Artificial DNA offers a comprehensive review that allows you to understand the strategy, design, and applications of synthetic oligonucleotides.

DKK 643.00
1

Revival: Topology and Physics of Circular DNA (1992) - Alexander Vologodskii - Bog - Taylor & Francis Ltd - Plusbog.dk

Revival: Topology and Physics of Circular DNA (1992) - Alexander Vologodskii - Bog - Taylor & Francis Ltd - Plusbog.dk

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

DKK 429.00
1

Interpreting Complex Forensic DNA Evidence - Jane Moira Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Interpreting Complex Forensic DNA Evidence - Jane Moira Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Interpreting Complex Forensic DNA Evidence is a handy guide to recent advances—and emerging issues—in interpreting complex DNA evidence and profiles for use in criminal investigations. In certain cases, DNA cannot be connected to a specific biological material such as blood, semen or saliva. How or when the DNA was deposited may be an issue. The possibility of generating DNA profiles from touched objects, where there may not be a visible deposit, has expanded the scope and number of exhibits submitted for DNA analysis. With such advances, and increasing improvements in technological capabilities in testing samples, this means it is possible to detect ever smaller amounts of DNA. There are also many efforts underway to seek was to interpret DNA profiles that are sub-optimal—either relative to the amount required by the testing kit and, potentially, the quality of the obtained sample. Laboratories often use enhancements in order to obtain a readable DNA profile. The broad-reaching implications of improving DNA sensitivity have led to this next, emerging generation of more complex profiles. Examples partial profiles that do not faithfully reflect the proposed donor, or mixtures of partial DNA from multiple people. A complexity threshold has been proposed to limit interpretation of poor-quality data. Research is now addressing the interpretation of transfer of trace amounts of DNA. Complex issues are arising in trial that need to be reconciled as such complexity has added challenges to the interpretation of evidence and its introduction or dismissal in certain cases in the courts. Key Features: Addresses DNA transfer, from person-to-person as well as to objects Outlines each stage required to produce a DNA profile from an exhibit—including collection, handling, storage, and analysis Discusses ethics, subjectivity, and bias—including cognitive dissonance—as they relate specifically to complex DNA evidence Highlights current techniques and the latest advances in DNA analysis, including advances in familial DNA searches Interpreting Complex Forensic DNA Evidence provides tools to assist the criminal investigator, forensic expert, and legal professional when posed with a DNA result in a forensic report or testimony. The result—and any associated statistic—may not reveal any ambiguity, complexity, or the assumptions involved in deriving it. Questions from resolved criminal cases are posed, and the relevant forensic literature, provided for the reader to assess a DNA result and any associated statistic. Case studies throughout illustrate concepts and emphasize the need for conclusions in the forensic report that are supported by the data.

DKK 590.00
1

Forensic DNA Profiling - Jo Anne Bright - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Profiling - Jo Anne Bright - Bog - Taylor & Francis Ltd - Plusbog.dk

DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

DKK 514.00
1

Nanostructures and Nanoconstructions based on DNA - S.g. Skuridin - Bog - Taylor & Francis Ltd - Plusbog.dk

Nanostructures and Nanoconstructions based on DNA - S.g. Skuridin - Bog - Taylor & Francis Ltd - Plusbog.dk

Evolutionally optimized biomolecules and their complexes present attractive objects in the production of functionalized nanoobjects. Indeed, nucleic acid-based molecules are primary candidates as building blocks for development of nanoscale systems and devices. Written for chemists, physicists, molecular biologists, and students in related fields, Nanostructures and Nanoconstructions Based on DNA covers specific properties of metallic nanoparticles, and compares their properties with those related to nanoobjects formed by biological molecules. It also discloses details of formation and physicochemical peculiarities of the DNA nanostructures and DNA-based nanoconstructions. Furthermore, the book considers: - - The peculiarities of two approaches to structural DNA nanotechnology, i.e. to creation of spatial nanoobjects formed by DNA molecules and their complexes: (i) the hybridization approach and (ii) the liquid-crystalline approach - The physicochemical properties of DNA nanostructures as well as "liquid" and "rigid" DNA-based nanoconstructions - The connection of liquid crystalline phase formation in DNA with possible nanotechnological applications - This timely reference covers more DNA physics and molecular biology than any other published title. The authors discuss how nucleic acid molecules and their complexes with chemical and biologically active compounds are an area of increasing significance in the development of various nanoscale systems and devices of practical importance.

DKK 643.00
1

Interpreting Complex Forensic DNA Evidence - Jane Moira (greensboro Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Interpreting Complex Forensic DNA Evidence - Jane Moira (greensboro Taupin - Bog - Taylor & Francis Ltd - Plusbog.dk

Interpreting Complex Forensic DNA Evidence is a handy guide to recent advances—and emerging issues—in interpreting complex DNA evidence and profiles for use in criminal investigations. In certain cases, DNA cannot be connected to a specific biological material such as blood, semen or saliva. How or when the DNA was deposited may be an issue. The possibility of generating DNA profiles from touched objects, where there may not be a visible deposit, has expanded the scope and number of exhibits submitted for DNA analysis. With such advances, and increasing improvements in technological capabilities in testing samples, this means it is possible to detect ever smaller amounts of DNA. There are also many efforts underway to seek was to interpret DNA profiles that are sub-optimal—either relative to the amount required by the testing kit and, potentially, the quality of the obtained sample. Laboratories often use enhancements in order to obtain a readable DNA profile. The broad-reaching implications of improving DNA sensitivity have led to this next, emerging generation of more complex profiles. Examples partial profiles that do not faithfully reflect the proposed donor, or mixtures of partial DNA from multiple people. A complexity threshold has been proposed to limit interpretation of poor-quality data. Research is now addressing the interpretation of transfer of trace amounts of DNA. Complex issues are arising in trial that need to be reconciled as such complexity has added challenges to the interpretation of evidence and its introduction or dismissal in certain cases in the courts. Key Features: Addresses DNA transfer, from person-to-person as well as to objects Outlines each stage required to produce a DNA profile from an exhibit—including collection, handling, storage, and analysis Discusses ethics, subjectivity, and bias—including cognitive dissonance—as they relate specifically to complex DNA evidence Highlights current techniques and the latest advances in DNA analysis, including advances in familial DNA searches Interpreting Complex Forensic DNA Evidence provides tools to assist the criminal investigator, forensic expert, and legal professional when posed with a DNA result in a forensic report or testimony. The result—and any associated statistic—may not reveal any ambiguity, complexity, or the assumptions involved in deriving it. Questions from resolved criminal cases are posed, and the relevant forensic literature, provided for the reader to assess a DNA result and any associated statistic. Case studies throughout illustrate concepts and emphasize the need for conclusions in the forensic report that are supported by the data.

DKK 731.00
1

Dogs in Schools - Helen Lewis - Bog - Taylor & Francis Ltd - Plusbog.dk

Dogs in Schools - Helen Lewis - Bog - Taylor & Francis Ltd - Plusbog.dk

Using a wealth of infographics and classroom examples, Dogs in Schools sets out the pedagogical principles that schools can employ to work with school dogs in a way that promotes the well-being of all participants and creates a safe environment for all. This is the first book to combine theory and research with the views of experienced teachers and professionals working around the world, from the United Kingdom to India, from Australia to mainland Europe. Their perspectives illustrate the wide-ranging interest in school dogs but also highlight common concerns. For policymakers, this is a book not to ignore because it shows how dogs have the potential to make a significant contribution to children''s well-being at a time of growing concern in this area. Simultaneously, the authors endorse the views of contributors who call for the introduction of humane regulations and fulsome guidance so that school dogs are viewed as sentient companions and not relegated to the latest educational fad. This is a must-read book for all those who are serious about humane education and ensuring the well-being and happiness of both children and dogs.

DKK 325.00
1

Advances in Forensic Biology and DNA Typing - Amarnath Mishra - Bog - Taylor & Francis Ltd - Plusbog.dk

Advances in Forensic Biology and DNA Typing - Amarnath Mishra - Bog - Taylor & Francis Ltd - Plusbog.dk

Advances in Forensic Biology and DNA Typing examines a broad range of forensic DNA applications and topics, based on internationally recognized best practices. A contributed volume that includes chapters by experts from around the world, the book covers a broad range of forensic DNA applications and topics. This includes trace and touch DNA, microarray analyses, DNA transfer and persistence, extraction methods, DNA recover in mass disasters, non-destructive methods for testing, forensic investigative genetic genealogy (FIGG) as well as other technologies and emergent techniques in the field. The manual also explores the development and usage of in forensic biology for the analysis of non-human samples. Key features: - Highlights sources of DNA (including biological fluids, hair, bones, teeth) detailing how to address the challenges of various sample types, quantities, and environmental factors - Presents best practices in investigative and collection procedures, as well as evaluative and testing methods, of biological samples - Addresses both human and non-human DNA analyses and applications for both criminal and wildlife investigations Advances in Forensic Biology and DNA Typing is a highly illustrated guide that will serve as a useful reference for forensic laboratory professionals, investigators, and students, as well as legal professionals.

DKK 772.00
1

Forensic DNA Analyses Made Simple - Ewen Mclean - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Analyses Made Simple - Ewen Mclean - Bog - Taylor & Francis Ltd - Plusbog.dk

Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer. Key Features • Provides self-learning about DNA fingerprinting. • Includes sections on how to analyze and interpret DNA fingerprinting. • Covers legal and medicolegal issues and case analyses. • Teaches novice legal community about DNA fingerprints. • Summarizes for a general audience the role of ancestry, DNA, and what that means.

DKK 410.00
1

Forensic DNA Analyses Made Simple - Omar Bagasra - Bog - Taylor & Francis Ltd - Plusbog.dk

Forensic DNA Analyses Made Simple - Omar Bagasra - Bog - Taylor & Francis Ltd - Plusbog.dk

Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer. Key Features • Provides self-learning about DNA fingerprinting. • Includes sections on how to analyze and interpret DNA fingerprinting. • Covers legal and medicolegal issues and case analyses. • Teaches novice legal community about DNA fingerprints. • Summarizes for a general audience the role of ancestry, DNA, and what that means.

DKK 1042.00
1

Working With DNA - Stan Metzenberg - Bog - Taylor & Francis Ltd - Plusbog.dk

Working With DNA - Stan Metzenberg - Bog - Taylor & Francis Ltd - Plusbog.dk

Working with DNA is a guide to the materials and methods that are used in the recombinant DNA laboratory and is designed to help the novice understand how specific laboratory techniques work, but also has sections that may stimulate the thinking of experienced researchers. It isn''t a book of step-by-step protocols and recipes, but is intended to broaden and strengthen the foundation of the reader so that working with DNA becomes more natural and make them aware of the many ways that a molecular research question may be addressed.

DKK 590.00
1

Police and Military Dogs - John Ensminger - Bog - Taylor & Francis Ltd - Plusbog.dk

Police and Military Dogs - John Ensminger - Bog - Taylor & Francis Ltd - Plusbog.dk

It is essential that those in the criminal justice system understand the tasks that police dogs perform and the evidence that their work produces. Police and Military Dogs: Criminal Detection, Forensic Evidence, and Judicial Admissibility examines the use of police and military dogs for a wide variety of functions and explores canine biology and behavior as it applies to police work. The book begins with an overview of the changes that have occurred in the field in the past four decades as discoveries have been made about canine capabilities. The author examines how a canine handler’s work with a skilled police dog can affect the subsequent investigation and prosecution of the crime. He discusses optimal procedures for finding and processing evidence and describes the boundaries of admissibility of evidence produced by police dogs. The book examines the many diverse detection functions police dogs are being trained to perform, ranging from cadaver detection to the discovery of explosives. It also describes the use of dogs to apprehend criminals and in search and rescue operations. Written for a wide audience including canine handlers, forensic scientists, attorneys, and the judiciary, this volume covers topics pertinent to all aspects of the police dog in contemporary law enforcement.

DKK 373.00
1

Materials Science of DNA - - Bog - Taylor & Francis Ltd - Plusbog.dk

Materials Science of DNA - - Bog - Taylor & Francis Ltd - Plusbog.dk

The field of materials science and technology has undergone revolutionary advances due to the development of novel analytical tools, functional materials, and multidisciplinary approaches to engineering. Additionally, theoretical predictions combined with increasingly improved models and computational capabilities are making impressive contributions to the progress of materials science and technology. In particular, the materials science of DNA has emerged as a vital area of research and is expected to immensely broaden the horizon of material science and nanotechnology in this century. Materials Science of DNA highlights the most important subjects and perspectives in the field, with the aim of stimulating the interdisciplinary community and bringing this intensively interesting, emerging field of molecular-scale materials science to maturation. The editors have not only been involved in the research of materials science of DNA for the past decade, but also lead the series of International Biotronics Workshops supported by the US Air Force Research Laboratory. Biotechnology and DNA-based biopolymers are not only applicable for genomic sequencing and clinical diagnosis and treatment, but can also have a major impact on nonbiotech applications—such as electronics and photonics— opening up a whole new field for bioengineering. New concepts and insights gained from DNA research are expected to prove genuinely useful in a variety of devices in nano, micro, and macro dimensions in the future. Where silicon has been the building block of inorganic electronics and photonics, DNA holds promise to become the building block for organic electronics and photonics.

DKK 514.00
1

DNA Analysis for Missing Person Identification in Mass Fatalities - Amanda C Sozer - Bog - Taylor & Francis Ltd - Plusbog.dk

DNA Analysis for Missing Person Identification in Mass Fatalities - Amanda C Sozer - Bog - Taylor & Francis Ltd - Plusbog.dk

Advances in DNA technology have expanded such that forensic DNA profiling is now considered a routine method for identifying victims of mass fatalities. Originating from an initiative funded by a grant from the U.S. Department of State, DNA Analysis for Missing Person Identification in Mass Fatalities presents a collection of training modules that supply comprehensive instruction in these complex techniques. The book begins with a concise overview of DNA analysis methods and their use in identifying victims of mass fatalities. It then goes on to explore: - - Mass fatality response operations, including body recovery, mortuary operations, family assistance, the identification of human remains, and psychosocial support for families - - - Best practices in DNA sample collection and the different types of reference samples that can be used to identify a reported missing (RM) individual - - - Autosomal short tandem repeat (STR) DNA profile analysis and interpretation, and procedures to ensure data accuracy - - - Major steps involved in generating a DNA profile and the complex aspects of data analysis and interpretation - - - The importance of data management using information technology tools, and tips for maintaining quality operations - - - Accreditation and standards and the major elements of a DNA quality program - - - Setting up a laboratory operation, including planning, staffing, identifying types of equipment and supplies, and the procedures for ensuring that laboratory equipment performs appropriately - The book includes a discussion of the key steps in the preparation, delivery, and evaluation of training sessions for personnel responding to a mass fatality human identification event. It also provides a comprehensive vocabulary list with terms related to mass fatality DNA identification. This text is a must-read for organizations contemplating the use of DNA in human identification initiatives following mass fatalities. It is also a tremendous value to emergency manager/planners, medical legal authorities, and forensic DNA laboratories.

DKK 745.00
1

DNA Liquid-Crystalline Dispersions and Nanoconstructions - Yuri M. Yevdokimov - Bog - Taylor & Francis Ltd - Plusbog.dk

DNA Liquid-Crystalline Dispersions and Nanoconstructions - Yuri M. Yevdokimov - Bog - Taylor & Francis Ltd - Plusbog.dk

The discovery of the spatial structure of the double-stranded DNA molecule is one of the greatest achievements of science. It would not be an exaggeration to say that the DNA double helix is a distinguished symbol of modern biology. Divided into three parts, DNA Liquid-Crystalline Dispersions and Nanoconstructions covers the information presently available on the condensation of various forms of DNA and describes practical applications of the peculiar properties of the liquid-crystalline particles. - Part 1 describes the main methods used for condensation of linear high- and low-molecular mass DNA, including their complexes with polycations and circular DNA - Part 2 compares the state and reactivity of double-stranded nucleic acid molecules fixed spatially in the liquid-crystalline as well as the same molecules under intracellular conditions - Part 3 explains how the discovery of the fundamental principles underlying the formation of nucleic acid liquid-crystalline dispersion particles opens a gate for the operational use of these principles in the area of nanotechnology and biosensorics With detailed coverage of DNA liquid crystals, this book provides an understanding of the information presently available on the condensation of various forms of DNA. Double-stranded nucleic acids, spatially organized in a liquid-crystalline structure, represent an important polyfunctional tool for molecular biology and nanobiotechnology. The possibility of programmed and controlled variations in the properties of these molecules and in the characteristics of their liquid-crystalline dispersions, provides wide options for the formation of biologically active three-dimensional structures with unique, widely applicable properties.

DKK 637.00
1

Environmental Damage to DNA and the Protective Effects of Phytochemicals - Bechan Sharma - Bog - Taylor & Francis Ltd - Plusbog.dk

Environmental Damage to DNA and the Protective Effects of Phytochemicals - Bechan Sharma - Bog - Taylor & Francis Ltd - Plusbog.dk

Environmental Damage to DNA and the Protective Effects of Phytochemicals provides information on the toxicity of natural as well as synthetic chemicals in the living systems. These can lead to DNA damage and the emergence of serious consequences or manifestations causing varied health hazards. In addition, the ten chapters of the book reflect on the possible applications of plants or plant extracts to impart protection for living cells from the xenobiotics-mediated DNA damage. The book offers comprehensive coverage of the many essential topics in the subject including: - - Environmental factors and DNA damage - - - Molecular mechanisms associated with DNA damage by various environmental (Physical, Chemical and Biological) factors - - - Synergistic effects of environmental factors - - - Phytochemicals acting both as DNA protectants and genotoxicants - - - Experimental models for the study of the genotoxic potential of environmental factors and protection by phytochemicals This book connects readers who possess a life sciences background to the current understanding, concept and mechanisms involved in environmental-factors-mediated DNA damage. Scientific terms are introduced, defined, described and placed appropriately in the text. The protective effect of some plant extracts/phytochemicals has also been included. Environmental Damage to DNA and the Protective Effects of Phytochemicals is intended to cater the need of BSc, MSc and research students who are striving to discover the mechanism(s) associated with protection of DNA by plant-based chemicals. This is the first edition of our book and the valuable suggestions and comments from the readers are solicited.

DKK 532.00
1