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The Essential Guide to Vitamin D - - Bog - Nova Science Publishers Inc - Plusbog.dk

The Essential Guide to Vitamin D - - Bog - Nova Science Publishers Inc - Plusbog.dk

This guide first discusses vitamin D receptor, a member of the superfamily of nuclear steroid/thyroid hormone receptors that can be found in both the cytoplasm and nucleus. It acts mainly as a ligand-dependent DNA-binding transcriptional factor mediating the actions of the biological active form of vitamin D (VD), the metabolite 1α,25[OH]2D3. Vitamin D has a complex role in the human body. Beside the classical effects in bone mineralisation, a significant amount of data regarding the role of this vitamin in cell differentiation, defence mechanism, allergy, inflammation, metabolism and hormonal regulation continue to accumulate. As such, the relevance of these effects for lung disorders is under investigation. Vitamin D is a hormone with pleiotropic effects; it controls calcium homeostasis, immune response, and hemodynamic wall stress. In the last decade, numerous studies have focused on the role of vitamin D levels in cardiovascular disease. In particular, it has been shown that insufficient Vitamin D levels are frequently observed among patients with cardiovascular disease. Additionally, calcitriol, which is also called 1, 25-dihydroxy vitamin D3, is involved in several physiological processes maintaining balanced bone turnover and a healthy bone microenvironment. The beneficial effects of vitamin D on bone biomechanical features are not exclusively attributable to the reduction in non-mineralised bone matrix, but to the osteocyte number and their connectivity, too. Studies have reported that Vitamin D is essential for recovery of hospitalised patients as they are at increased risk of developing/worsening vitamin D deficiency due to lack of availability of sources of the vitamin. Various cognitive disorders have also been associated with hypovitaminosis D. Vitamin D has also been proposed as a risk-modifying factor for many chronic diseases, including multiple sclerosis, schizophrenia, cognitive issues, hypertension, heart disease, diabetes, cancer, psoriasis, and other autoimmune diseases. Vitamin D deficiency is the main cause of osteoporosis and osteomalacia in adults and rickets in children. The low serum of this vitamin is common in patients suffering from cardiovascular, autoimmune, cancer, psoriasis, depression and atherosclerosis disorder. The highly sensitive nature of vitamin D to environmental factors including light, heat, and oxygen, as well as hydrophobicity and acid labile nature, are the major drawbacks that need to be addressed for development of an efficient formulation for vitamin D.

DKK 890.00
1

Vitamin D, An Issue of Endocrinology and Metabolism Clinics of North America - Daniel Bikle - Bog - Elsevier - Health Sciences Division - Plusbog.dk

Randomization Tests - Eugene Edgington - Bog - Taylor & Francis Inc - Plusbog.dk

Optimum Vitamin Nutrition for More Sustainable Aquaculture - Ester Santigosa - Bog - 5M Books Ltd - Plusbog.dk

Special Tests for Orthopedic Examination - Jeff G. Konin - Bog - Taylor & Francis Inc - Plusbog.dk

Special Tests for Orthopedic Examination - Jeff G. Konin - Bog - Taylor & Francis Inc - Plusbog.dk

First published more than 20 years ago, Special Tests for Orthopedic Examination , now in its Fourth Edition, continues to follow the authors’ initial goals of providing a simple, pocket-sized manual for practical learning purposes. The Fourth Edition provides critical and invaluable information on the most current and practical special tests used during an orthopedic examination. The efficient user-friendly, spiral-bound format allows for easy access to individualized special tests. Special Tests for Orthopedic Examination, Fourth Edition includes 160 special tests, 6 of which are new: - Ballottement Test - Gerber’s Test (Lift-Off Test) - Painful Arc Sign - Thessaly Test - Quad Active Test - Lelli Test for Anterior Cruciate Ligament (ACL) Injuries Inside Special Tests for Orthopedic Examination Fourth Edition , Jeff G. Konin, Denise Lebsack, Alison R. Snyder Valier, and Jerome A. Isear, Jr. have included a new section on evidence, where the authors have highlighted systematic reviews, meta-analyses, or single articles to address reliability, sensitivity, and specificity of the special tests, where available. What is new and updated in the Fourth Edition : - Includes a video website that provides visually enhanced dimensional and motion analysis of each special test performed - Includes 160 special tests, 6 of which are new to this edition - Includes information on reliability, sensitivity, and specificity presented in a table format - New evidence section highlight systematic reviews, meta-analyses, or single articles for special tests, where available - New color images for each test - Updated references for all tests Bonus Material! Special Tests for Orthopedic Examination, Fourth Edition includes a video website with each new book purchase. This video website offers a unique approach that provides a visually enhanced dimensional and motion analysis of each special test performed. The video segments will help students and clinicians better understand the test motion in order to perform the test accurately during an orthopedic examination. The simple yet succinct information provided throughout the manual and on the video website will help clinicians make informed decisions during an orthopedic examination, from understanding to performing and evaluating the special tests. Special Tests for Orthopedic Examination, Fourth Edition will carry on the tradition of past editions as being the premier resource for thousands of students, clinicians, and rehabilitation professionals.

DKK 863.00
1

Optimum Vitamin Nutrition for More Sustainable Poultry Farming - R. Cepero Briz - Bog - 5M Books Ltd - Plusbog.dk

Permutation Tests for Complex Data - L Salmaso - Bog - John Wiley & Sons Inc - Plusbog.dk

Permutation Tests for Complex Data - L Salmaso - Bog - John Wiley & Sons Inc - Plusbog.dk

Timely update of a popular edition on permutation testing with numerous case studies included throughout The newly revised and updated Second Edition of Permutation Tests for Complex Data describes permutation tests from the point of view of experimental design, with methodological details and illustrating the process of devising an appropriate permutation test through case studies. In addition to the text, this book includes two open source packages for permutation tests in Python and R which include a comprehensive code base to implement common permutation tests as well as code to implement each of the book's case studies. The focus of this book is the permutation approach to a variety of univariate and multivariate problems of hypothesis testing in a typical nonparametric framework. The book examines the most up-to-date methodologies of univariate and multivariate permutation testing, includes real case studies from both experimental and observational studies, and presents and discusses solutions to the most important and frequently encountered real problems in multivariate analyses. Written by two highly qualified authors in the field of nonparametrics and applied statistics, Permutation Tests for Complex Data includes information on sample topics including: Theory of one-dimensional and multi-dimensional permutation tests, covering test statistics, arguments for selecting permutation tests, and examples of one-sample and multi-sample problemsMultiplicity control and closed testing, covering raw and adjusted p-values, the MinP Bonferroni-Holm procedure, and weighted methods for controlling FWE and FDRMultivariate categorical variables, covering stochastic ordering, tests on moments for ordered variables, and heterogeneity comparisonsNPC tests for survival analysis and shape analysis, covering analysis of PERC data and analysis with correlated landmarks Presenting a thorough overview of permutation testing with both formal description and proofs, Permutation Tests for Complex Data is an excellent introduction to permutation tests for graduate-level statistics or data science courses and will be ideal as a handbook for researchers hoping to use the open source code.

DKK 1133.00
1

Orthopedic Physical Examination Tests: An Evidence-Based Approach - Chad Cook - Bog - Pearson Education Limited - Plusbog.dk

Year 2/P3 Reading Comprehension Progress Tests - - Bog - HarperCollins Publishers - Plusbog.dk

Evaluating Medical Tests - Helena Chmura Kraemer - Bog - SAGE Publications Inc - Plusbog.dk

Evaluating Medical Tests - Helena Chmura Kraemer - Bog - SAGE Publications Inc - Plusbog.dk

A growing body of medical research suggests that many medical tests used for diagnosis, prognosis, and monitoring response to treatment are unnecessary or inappropriate, yield inaccurate or misleading results, and add to the incidence of iatrogenic disease. Many such tests go into common clinical use without convincing documentation of their value because current methods for evaluating medical tests produce inconsistent results. Evaluating Medical Tests presents a systematic, objective methodology by which to determine the effectiveness of medical tests. Kraemer clearly and concisely shows how to define statistical terms and approaches consistently from study to study, how to stipulate statistical assumptions underlying various approaches, how to check for empirical validity, and how to judge the robustness of statistical outcomes, resulting in models that integrate many different approaches and extend the strengths of each. Statisticians, evaluators, researchers, practitioners, policymakers, and advanced students concerned with the evaluation of medical tests used to make clinical decisions for patient care and for research will find this essential, thought-provoking reading. "This volume is a pleasure to read. It succinctly combines carefully reasoned conceptualization with the mathematical methods for addressing test evaluation problems. With clinically relevant, illustrative examples, it draws on the author′s extensive experience and research in biomedical statistics. It should be required reading for medical students and practitioners. It is invaluable to researchers and statisticians, and it provides a logical, scientific basis for efforts at medical cost containment. It is a classic! --from the Foreword by A. John Rush, M.D. "This fascinating book integrates a wide range of statistical and methodological concepts, reflects a thorough introduction to the issues confronted by evaluators of [medical] tests, and challenges motivated readers to adopt these procedures in their own research. This is an exciting book, with obvious strong policy implications concerning the way that [medical] tests are evaluated and the need for standards in this regard. . . . Evaluating Medical Tests should be of interest to all professionals who depend on tests as an adjunct in the decision-making process." --Paul R. Yarnold Northwestern University Medical School "Dr. Kraemer has undertaken a most massive and laudable task in writing Evaluating Medical Tests. . . . Dr. Kraemer′s book stands as a flagship for those concerned to understand the reasons behind our escalating health care costs and the implications this holds for every American. . . . This leads us to one of the innovative features of Dr. Kraemer′s book: ′This is not merely a statistical issue, or merely a medical issue, it is a national policy issue of the greatest importance.′. . . She does not assume that her readers are either statisticians or physicians. As such, she skillfully guides one through the terrain of medical and statistical jargon and points our where the assumptions of the statistics are either not stipulated or incongruent with the medical test and data being evaluated, thus rendering results and interpretations suspect. Another plus of Dr. Kraemer′s writing is her willingness to use ′. . . the first person singular to differentiate . . . comments from presentations of what I would consider provable or documentable facts. . . ′ In so doing, she raised issues and calls medical professionals, policymakers, and patients into dialogue to consider the impact of the use of these various techniques in diagnosis. . . . Evaluating Medical Tests is of specific relevance to rehabilitation counselors who proceed with their clients through the maze of diagnostic and prognostic tests. . . . It is especially important for rehabilitation counselors who act as expert witnesses to have a working knowledge of this material to enhance their discussions with health care personnel." --Journal of Applied Rehabilitation Counseling

DKK 1029.00
1

Special Tests for Neurologic Examination - James R. Scifers - Bog - Taylor & Francis Inc - Plusbog.dk

Special Tests for Neurologic Examination - James R. Scifers - Bog - Taylor & Francis Inc - Plusbog.dk

Ideal for students and clinicians to access quick clinical information, Special Tests for Neurologic Examination offers invaluable evaluation and assessment tips and techniques for neurologic conditions commonly found in patients. Organized in an easy-to-use format, this book is the perfect guide for practicing clinical skills and reviewing for licensure and certification examinations. Dr. James R. Scifers describes and illustrates special tests for the upper extremity, lower extremity, and spine. This resource provides performance criteria for each special test, important information on specificity and sensitivity, and valuable references for further investigation. Inside you’ll find: • Techniques for dermatome, myotome, reflex screening, and concussion testing • Examples of various concussion grading scales and neuropsychological tests • Special design that facilitates use of the book as a user-friendly study guide and quick clinical reference • Data on test specificity and sensitivity to assist clinicians in determining the value and strength of various clinical examination procedures • Additional resources for further study and exploration A facilitative and comprehensive approach to learning, practicing, and reviewing neurologic special tests makes Special Tests for Neurologic Examination a must-have for students and clinicians alike. With a focus on commonly used evaluative procedures for differentiating and diagnosing neurologic disorders, the book serves as a valuable companion to the popular Special Tests for Orthopedic Examination.

DKK 863.00
1

Statistical Tests Of Nonparametric Hypotheses: Asymptotic Theory - Odile Pons - Bog - World Scientific Publishing Co Pte Ltd - Plusbog.dk

Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline - Food And Nutrition

Assessing Psychometric Fitness of Intelligence Tests - - Bog - Rowman & Littlefield - Plusbog.dk

Year 5/P6 Maths Progress Tests for White Rose - Rachel Axten Higgs - Bog - HarperCollins Publishers - Plusbog.dk

Year 2/P3 Spelling Half Termly Tests - Clare Dowdall - Bog - HarperCollins Publishers - Plusbog.dk

Year 1/P2 Spelling Half Termly Tests - Clare Dowdall - Bog - HarperCollins Publishers - Plusbog.dk

Year 5/P6 Spelling Half Termly Tests - Clare Dowdall - Bog - HarperCollins Publishers - Plusbog.dk

Year 4/P5 Spelling Half Termly Tests - Clare Dowdall - Bog - HarperCollins Publishers - Plusbog.dk