33 results (0,18359 seconds)

Brand

Merchant

Price (EUR)

Reset filter

Products
From
Shops

Thermal-Aware Testing of Digital VLSI Circuits and Systems

Multiple Testing Problems in Pharmaceutical Statistics

Multiple Testing Problems in Pharmaceutical Statistics

Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians scientists and clinicians from the pharmaceutical industry academia and regulatory agencies Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter the expert contributors describe important multiplicity problems encountered in pre-clinical and clinical trial settings. The book begins with a broad introduction from a regulatory perspective to different types of multiplicity problems that commonly arise in confirmatory controlled clinical trials before giving an overview of the concepts principles and procedures of multiple testing. It then presents statistical methods for analyzing clinical dose response studies that compare several dose levels with a control as well as statistical methods for analyzing multiple endpoints in clinical trials. After covering gatekeeping procedures for testing hierarchically ordered hypotheses the book discusses statistical approaches for the design and analysis of adaptive designs and related confirmatory hypothesis testing problems. The final chapter focuses on the design of pharmacogenomic studies based on established statistical principles. It also describes the analysis of data collected in these studies taking into account the numerous multiplicity issues that occur. This volume explains how to solve critical issues in multiple testing encountered in pre-clinical and clinical trial applications. It presents the necessary statistical methodology along with examples and software code to show how to use the methods in practice.

GBP 42.99
1

Ransomware Penetration Testing and Contingency Planning

The Waterside Ape An Alternative Account of Human Evolution

The Waterside Ape An Alternative Account of Human Evolution

Why are humans so fond of water? Why is our skin colour so variable? Why aren’t we hairy like our close ape relatives? A savannah scenario of human evolution has been widely accepted primarily due to fossil evidence; and fossils do not offer insight into these questions. Other alternative evolutionary scenarios might but these models have been rejected. This book explores a controversial idea – that human evolution was intimately associated with watery habitats as much or more than typical savannahs. Written from a medical point of view the author presents evidence supporting a credible alternative explanation for how humans diverged from our primate ancestors. Anatomical and physiological evidence offer insight into hairlessness different coloured skin subcutaneous fat large brains a marine-type kidney a unique heat regulation system and speech. This evidence suggests that humans may well have evolved not just as savannah mammals as is generally believed but with more affinity for aquatic habitats – rivers streams lakes and coasts. Key Features: Presents the evidence for a close association between riparian habitats and the origin of humans Reviews the savannah ape hypothesis for human origins Describes various anatomical adaptations that are associated with hypotheses of human evolution Explores characteristics from the head and neck such as skull and sinus structures the larynx and ear structures and functions | The Waterside Ape An Alternative Account of Human Evolution

GBP 24.99
1

Musculoskeletal Injections and Alternative Options A practical guide to 'what when and how?'

The Pocket Mentor for Video Game Testing

Pediatric Emergency Medicine Illustrated Clinical Cases Second Edition

Technical Analysis of Stock Trends

Get Through MRCOG Part 3 Clinical Assessment Second Edition

No-Frills Physics A Concise Study Guide for Algebra-Based Physics

Pesticide Regulation Handbook A Guide for Users

Revival: Principles of Seed Pathology (1987) Volume II

Game Design Tools Cognitive Psychological and Practical Approaches

Crossing Numbers of Graphs

Leadership and Governance in Primary Healthcare An Exemplar for Practice in Resource Limited Settings

The Potential Effect Of Two New Biotechnologies On The World Dairy Industry

An Introduction to Statistical Inference and Its Applications with R

The Easy Guide to Focused History Taking for OSCEs

Introduction to Spatial Econometrics

Handbook of Univariate and Multivariate Data Analysis with IBM SPSS

Handbook of Univariate and Multivariate Data Analysis with IBM SPSS

Using the same accessible hands-on approach as its best-selling predecessor the Handbook of Univariate and Multivariate Data Analysis with IBM SPSS Second Edition explains how to apply statistical tests to experimental findings identify the assumptions underlying the tests and interpret the findings. This second edition now covers more topics and has been updated with the SPSS statistical package for Windows. New to the Second EditionThree new chapters on multiple discriminant analysis logistic regression and canonical correlationNew section on how to deal with missing dataCoverage of tests of assumptions such as linearity outliers normality homogeneity of variance-covariance matrices and multicollinearityDiscussions of the calculation of Type I error and the procedure for testing statistical significance between two correlation coefficients obtained from two samples Expanded coverage of factor analysis path analysis (test of the mediation hypothesis) and structural equation modelingSuitable for both newcomers and seasoned researchers in the social sciences the handbook offers a clear guide to selecting the right statistical test executing a wide range of univariate and multivariate statistical tests via the Windows and syntax methods and interpreting the output results. The SPSS syntax files used for executing the statistical tests can be found in the appendix. Data sets employed in the examples are available on the book’s CRC Press web page.

GBP 42.99
1

Traffic and Pavement Engineering

Traffic and Pavement Engineering

Traffic and Pavement Engineering presents the latest engineering concepts techniques practices principles standard procedures and models that are applied and used to design and evaluate traffic systems road pavement structures and alternative transportation systems to ultimately achieve greater safety sustainability efficiency and cost-effectiveness. It provides in-depth coverage of the major areas of transportation engineering and includes a broad range of practical problems and solutions related to theory concepts practice and applications. Solutions for each problem follow step-by-step procedures that include the theory and the derivation of the formulas and computations where applicable. Additionally numerical methods linear algebraic methods and least squares regression techniques are presented to assist in problem solving. Features: Presents coverage of major areas in transportation engineering: traffic engineering and pavement materials analysis and design. Provides solutions to numerous practical problems in traffic and pavement engineering including terminology theory practice computation and design. Offers downloadable and user-friendly MS Excel spreadsheets as well as numerical methods and optimization tools and techniques. Includes several practical case studies throughout. Utilizes a unique approach in presenting the different topics of transportation engineering. Traffic and Pavement Engineering will help academics and professionals alike to find practical solutions across the broad spectrum of traffic and pavement engineering issues.

GBP 42.99
1

Nutrition and Integrative Medicine for Clinicians Volume Two

Nutrition and Integrative Medicine for Clinicians Volume Two

Mystery illnesses can be helped this book lays the groundwork for it. Building on its predecessor this new volume Nutrition and Integrative Medicine for Clinicians is an essential peer-reviewed resource for practitioners those in allied health care and complementary/alternative medicine. The book contains valuable information for healthcare providers to use by helping patients manage treat and even prevent illnesses and put them on a healthy path to recovery. This volume contains information on various subjects including: · Illnesses resulting from water damaged buildings and subsequent change in the microbiome of the building · Steps to heal from mold/mycotoxin illnesses · Effects of CIRS on metabolism and insulin resistance · Pediatric sleep-related breathing disorders and their effects on growth and development · Environmental hormone disruptors · Myalgic encephalitis/chronic fatigue syndrome · Regenerative agriculture · Circadian effects of artificial light and their effects on mitochondria · Nutritional support for Covid · The human body as a biological sound healing instrument · Art in medicine · Living life with intention and mindfulness · Making childbirth a positive experience Written by authors at the forefront of their respective fields this book presents information for people “written off” as having a “mystery illness. ” It is a comprehensive guide on evaluating illnesses that are difficult to diagnose. | Nutrition and Integrative Medicine for Clinicians Volume Two

GBP 42.99
1

RCSI Handbook of Clinical Surgery for Finals

RCSI Handbook of Clinical Surgery for Finals

Developed over previous editions by the Royal College of Surgeons in Ireland to support students attending the three RCSI universities this convenient handbook provides pragmatic guidance to the principles and practice of surgery that students can expect to encounter during undergraduate studies. Spanning the full range of surgical specialties information is presented in a convenient and clinically relevant format that takes the students through the patient journey from presenting symptoms and aetiology to investigations management and follow-up. The text written as easy-to-read and easy-to-remember bullet lists is supplemented throughout by tables management algorithms and colour illustrations. Key Features: • Concise – specifically for the undergraduate medical student by a highly experienced team of surgical educators • Accessible – bullet text ideal for rapid reference • Flexible – for use when on the ward and during finals revision • Complete - print book supplemented by video clips online question and answer material and an image library for the full learning and revision package Thoroughly updated this fifth edition has enhanced pedagogy and for the first time is accompanied by video clips and questions for self-testing. Covering the core surgical knowledge needed to become a safe and competent doctor the book will be an invaluable companion for clinical placements and during the critical run-up to final examinations. | RCSI Handbook of Clinical Surgery for Finals

GBP 36.99
1