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DNA Methylation Microarrays Experimental Design and Statistical Analysis

DNA Methylation Microarrays Experimental Design and Statistical Analysis

Providing an interface between dry-bench bioinformaticians and wet-lab biologists DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data in particular DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies. After introducing basic statistics the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor) public databases and other online resources available for microarray research. Requiring only limited knowledge of statistics and programming this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis. | DNA Methylation Microarrays Experimental Design and Statistical Analysis

GBP 59.99
1

Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R

Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R

Analyzing high-dimensional gene expression and DNA methylation data with R is the first practical book that shows a ``pipeline of analytical methods with concrete examples starting from raw gene expression and DNA methylation data at the genome scale. Methods on quality control data pre-processing data mining and further assessments are presented in the book and R programs based on simulated data and real data are included. Codes with example data are all reproducible. Features: · Provides a sequence of analytical tools for genome-scale gene expression data and DNA methylation data starting from quality control and pre-processing of raw genome-scale data. · Organized by a parallel presentation with explanation on statistical methods and corresponding R packages/functions in quality control pre-processing and data analyses (e. g. clustering and networks). · Includes source codes with simulated and real data to reproduce the results. Readers are expected to gain the ability to independently analyze genome-scaled expression and methylation data and detect potential biomarkers. This book is ideal for students majoring in statistics biostatistics and bioinformatics and researchers with an interest in high dimensional genetic and epigenetic studies.

GBP 66.99
1

Equivalence and Noninferiority Tests for Quality Manufacturing and Test Engineers

Equivalence and Noninferiority Tests for Quality Manufacturing and Test Engineers

In engineering and quality control various situations including process validation and design verification require equivalence and noninferiority tests. Equivalence and Noninferiority Tests for Quality Manufacturing and Test Engineers presents methods for using validation and verification test data to demonstrate equivalence and noninferiority in engineering and applied science. The book covers numerous tests drawn from the author’s more than 30 years of work in a range of industrial settings. It provides computational formulas for the tests methods to determine or justify sample sizes and formulas to calculate power and operating characteristic curves. The methods are accessible using standard statistical software and do not require complicated programming. The book also includes computer code and screen shots for SAS R and JMP. This book provides you with a guide to performing validation and verification tests that demonstrate the adequacy of your process system or product. It will help you choose the best test for your application.

GBP 59.99
1

Nonparametric Statistical Tests A Computational Approach

Nonparametric Statistical Tests A Computational Approach

Nonparametric Statistical Tests: A Computational Approach describes classical nonparametric tests as well as novel and little-known methods such as the Baumgartner-Weiss-Schindler and the Cucconi tests. The book presents SAS and R programs allowing readers to carry out the different statistical methods such as permutation and bootstrap tests. The author considers example data sets in each chapter to illustrate methods. Numerous real-life data from various areas including the bible and their analyses provide for greatly diversified reading. The book covers: Nonparametric two-sample tests for the location-shift model specifically the Fisher-Pitman permutation test the Wilcoxon rank sum test and the Baumgartner-Weiss-Schindler test Permutation tests location-scale tests tests for the nonparametric Behrens-Fisher problem and tests for a difference in variability Tests for the general alternative including the (Kolmogorov-)Smirnov test ordered categorical and discrete numerical data Well-known one-sample tests such as the sign test and Wilcoxon’s signed rank test a modification suggested by Pratt (1959) a permutation test with original observations and a one-sample bootstrap test are presented. Tests for more than two groups the following tests are described in detail: the Kruskal-Wallis test the permutation F test the Jonckheere-Terpstra trend test tests for umbrella alternatives and the Friedman and Page tests for multiple dependent groups The concepts of independence and correlation and stratified tests such as the van Elteren test and combination tests The applicability of computer-intensive methods such as bootstrap and permutation tests for non-standard situations and complex designs Although the major development of nonparametric methods came to a certain end in the 1970s their importance undoubtedly persists. What is still needed is a computer assisted evaluation of their main properties. This book closes that gap. | Nonparametric Statistical Tests A Computational Approach

GBP 69.99
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Statistical Inference Based on Divergence Measures

Statistical Inference Based on Divergence Measures

The idea of using functionals of Information Theory such as entropies or divergences in statistical inference is not new. However in spite of the fact that divergence statistics have become a very good alternative to the classical likelihood ratio test and the Pearson-type statistic in discrete models many statisticians remain unaware of this powerful approach. Statistical Inference Based on Divergence Measures explores classical problems of statistical inference such as estimation and hypothesis testing on the basis of measures of entropy and divergence. The first two chapters form an overview from a statistical perspective of the most important measures of entropy and divergence and study their properties. The author then examines the statistical analysis of discrete multivariate data with emphasis is on problems in contingency tables and loglinear models using phi-divergence test statistics as well as minimum phi-divergence estimators. The final chapter looks at testing in general populations presenting the interesting possibility of introducing alternative test statistics to classical ones like Wald Rao and likelihood ratio. Each chapter concludes with exercises that clarify the theoretical results and present additional results that complement the main discussions. Clear comprehensive and logically developed this book offers a unique opportunity to gain not only a new perspective on some standard statistics problems but the tools to put it into practice.

GBP 44.99
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Handbook of Forensic Statistics

Handbook of Forensic Statistics

Handbook of Forensic Statistics is a collection of chapters by leading authorities in forensic statistics. Written for statisticians scientists and legal professionals having a broad range of statistical expertise it summarizes and compares basic methods of statistical inference (frequentist likelihoodist and Bayesian) for trace and other evidence that links individuals to crimes the modern history and key controversies in the field and the psychological and legal aspects of such scientific evidence. Specific topics include uncertainty in measurements and conclusions; statistically valid statements of weight of evidence or source conclusions; admissibility and presentation of statistical findings; and the state of the art of methods (including problems and pitfalls) for collecting analyzing and interpreting data in such areas as forensic biology chemistry and pattern and impression evidence. The particular types of evidence that are discussed include DNA latent fingerprints firearms and toolmarks glass handwriting shoeprints and voice exemplars.

GBP 66.99
1

Handbook of Educational Measurement and Psychometrics Using R

Handbook of Educational Measurement and Psychometrics Using R

Currently there are many introductory textbooks on educational measurement and psychometrics as well as R. However there is no single book that covers important topics in measurement and psychometrics as well as their applications in R. The Handbook of Educational Measurement and Psychometrics Using R covers a variety of topics including classical test theory; generalizability theory; the factor analytic approach in measurement; unidimensional multidimensional and explanatory item response modeling; test equating; visualizing measurement models; measurement invariance; and differential item functioning. This handbook is intended for undergraduate and graduate students researchers and practitioners as a complementary book to a theory-based introductory or advanced textbook in measurement. Practitioners and researchers who are familiar with the measurement models but need to refresh their memory and learn how to apply the measurement models in R would find this handbook quite fulfilling. Students taking a course on measurement and psychometrics will find this handbook helpful in applying the methods they are learning in class. In addition instructors teaching educational measurement and psychometrics will find our handbook as a useful supplement for their course.

GBP 44.99
1

Introduction to Machine Learning and Bioinformatics

Introduction to Machine Learning and Bioinformatics

Lucidly Integrates Current Activities Focusing on both fundamentals and recent advances Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other. Examines Connections between Machine Learning & Bioinformatics The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation the authors explore how machine learning techniques apply to bioinformatics problems such as electron density map interpretation biclustering DNA sequence analysis and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website. Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems Shedding light on aspects of both machine learning and bioinformatics this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today’s biological experiments.

GBP 59.99
1

Basic Statistics and Pharmaceutical Statistical Applications

Basic Statistics and Pharmaceutical Statistical Applications

Building on its best-selling predecessors Basic Statistics and Pharmaceutical Statistical Applications Third Edition covers statistical topics most relevant to those in the pharmaceutical industry and pharmacy practice. It focuses on the fundamentals required to understand descriptive and inferential statistics for problem solving. Incorporating new material in virtually every chapter this third edition now provides information on software applications to assist with evaluating data. New to the Third EditionUse of Excel® and Minitab® for performing statistical analysisDiscussions of nonprobability sampling procedures determining if data is normally distributed evaluation of covariances and testing for precision equivalenceExpanded sections on regression analysis chi square tests tests for trends with ordinal data and tests related to survival statistics Additional nonparametric procedures including the one-sided sign test Wilcoxon signed-ranks test and Mood’s median testWith the help of flow charts and tables the author dispels some of the anxiety associated with using basic statistical tests in the pharmacy profession and helps readers correctly interpret their results using statistical software. Through the text’s worked-out examples readers better understand how the mathematics works the logic behind many of the equations and the tests’ outcomes.

GBP 44.99
1

Theory of Statistical Inference

Theory of Statistical Inference

Theory of Statistical Inference is designed as a reference on statistical inference for researchers and students at the graduate or advanced undergraduate level. It presents a unified treatment of the foundational ideas of modern statistical inference and would be suitable for a core course in a graduate program in statistics or biostatistics. The emphasis is on the application of mathematical theory to the problem of inference leading to an optimization theory allowing the choice of those statistical methods yielding the most efficient use of data. The book shows how a small number of key concepts such as sufficiency invariance stochastic ordering decision theory and vector space algebra play a recurring and unifying role. The volume can be divided into four sections. Part I provides a review of the required distribution theory. Part II introduces the problem of statistical inference. This includes the definitions of the exponential family invariant and Bayesian models. Basic concepts of estimation confidence intervals and hypothesis testing are introduced here. Part III constitutes the core of the volume presenting a formal theory of statistical inference. Beginning with decision theory this section then covers uniformly minimum variance unbiased (UMVU) estimation minimum risk equivariant (MRE) estimation and the Neyman-Pearson test. Finally Part IV introduces large sample theory. This section begins with stochastic limit theorems the δ-method the Bahadur representation theorem for sample quantiles large sample U-estimation the Cramér-Rao lower bound and asymptotic efficiency. A separate chapter is then devoted to estimating equation methods. The volume ends with a detailed development of large sample hypothesis testing based on the likelihood ratio test (LRT) Rao score test and the Wald test. Features This volume includes treatment of linear and nonlinear regression models ANOVA models generalized linear models (GLM) and generalized estimating equations (GEE). An introduction to decision theory (including risk admissibility classification Bayes and minimax decision rules) is presented. The importance of this sometimes overlooked topic to statistical methodology is emphasized. The volume emphasizes throughout the important role that can be played by group theory and invariance in statistical inference. Nonparametric (rank-based) methods are derived by the same principles used for parametric models and are therefore presented as solutions to well-defined mathematical problems rather than as robust heuristic alternatives to parametric methods. Each chapter ends with a set of theoretical and applied exercises integrated with the main text. Problems involving R programming are included. Appendices summarize the necessary background in analysis matrix algebra and group theory.

GBP 99.99
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Molecular and Cellular Biophysics

Molecular and Cellular Biophysics

From quantum theory to statistical mechanics the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses this textbook features a quantitative approach that avoids being too abstract in its presentation. Logically organized from small-scale (molecular) to large-scale (cellular) systems the text first defines life discussing the scientific controversies between mechanists and vitalists the characteristics of living things and the evolution of life. It then delves into molecular structures including nucleic acids DNA RNA interatomic interactions and hydrogen bonds. After looking at these smaller systems the author probes the larger cellular structures. He examines the cytoplasm the cytoskeleton chromosomes mitochondria motor proteins and more. The book concludes with discussions on biophysical processes including oxidative phosphorylation diffusion bioenergetics conformational transitions in proteins vesicle transport subcellular structure formation and cell division.

GBP 59.99
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Self Assembly The Science of Things That Put Themselves Together

Self Assembly The Science of Things That Put Themselves Together

Hailed as one of the key areas of nanoscience likely to shape future scientific research self-assembly offers the most promising route to true molecular nanotechnology. Focusing on this dynamic new field Self Assembly: The Science of Things That Put Themselves Together explores nature's self-assembly of structures the use of it to build engineered systems and the latest advances in the field. Reflecting the inherent progress of the science of self-assembly this definitive book first delves into natural self-assembling systems. It addresses crystal growth soap films and micelles; examines how nature builds viruses proteins and ribosomes; and introduces the protein folding problem. The author then discusses how physicists chemists biologists and engineers are applying nature's principles to self-assemble everything from DNA cubes to millimeter-scale electronic circuits. The final chapters cover theoretical and experimental approaches to understand the phenomenon of self-assembly and overcome its various challenges. With practical activities profiles of leading experts chapter highlights exercises and references Self Assembly provides the most current authoritative information on this exciting branch of nanoscience. | Self Assembly The Science of Things That Put Themselves Together

GBP 180.00
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Bioinformatics A Practical Approach

Bioinformatics A Practical Approach

An emerging ever-evolving branch of science bioinformatics has paved the way for the explosive growth in the distribution of biological information to a variety of biological databases including the National Center for Biotechnology Information. For growth to continue in this field biologists must obtain basic computer skills while computer specialists must possess a fundamental understanding of biological problems. Bridging the gap between biology and computer science Bioinformatics: A Practical Approach assimilates current bioinformatics knowledge and tools relevant to the omics age into one cohesive concise and self-contained volume. Written by expert contributors from around the world this practical book presents the most state-of-the-art bioinformatics applications. The first part focuses on genome analysis common DNA analysis tools phylogenetics analysis and SNP and haplotype analysis. After chapters on microarray SAGE regulation of gene expression miRNA and siRNA the book presents widely applied programs and tools in proteome analysis protein sequences protein functions and functional annotation of proteins in murine models. The last part introduces the programming languages used in biology website and database design and the interchange of data between Microsoft Excel and Access. Keeping complex mathematical deductions and jargon to a minimum this accessible book offers both the theoretical underpinnings and practical applications of bioinformatics. | Bioinformatics A Practical Approach

GBP 59.99
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Solution Techniques for Elementary Partial Differential Equations

Solution Techniques for Elementary Partial Differential Equations

In my opinion this is quite simply the best book of its kind that I have seen thus far. —Professor Peter Schiavone University of Alberta from the Foreword to the Fourth Edition Praise for the previous editions An ideal tool for students taking a first course in PDEs as well as for the lecturers who teach such courses. —Marian Aron Plymouth University UK This is one of the best books on elementary PDEs this reviewer has read so far. Highly recommended. —CHOICE Solution Techniques for Elementary Partial Differential Equations Fourth Edition remains a top choice for a standard undergraduate-level course on partial differential equations (PDEs). It provides a streamlined direct approach to developing students’ competence in solving PDEs and offers concise easily understood explanations and worked examples that enable students to see the techniques in action. New to the Fourth Edition Two additional sections A larger number and variety of worked examples and exercises A companion pdf file containing more detailed worked examples to supplement those in the book which can be used in the classroom and as an aid to online teaching

GBP 56.99
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Grid Computing Techniques and Applications

Grid Computing Techniques and Applications

Designed for senior undergraduate and first-year graduate students Grid Computing: Techniques and Applications shows professors how to teach this subject in a practical way. Extensively classroom-tested it covers job submission and scheduling Grid security Grid computing services and software tools graphical user interfaces workflow editors and Grid-enabling applications. The book begins with an introduction that discusses the use of a Grid computing Web-based portal. It then examines the underlying action of job submission using a command-line interface and the use of a job scheduler. After describing both general Internet security techniques and specific security mechanisms developed for Grid computing the author focuses on Web services technologies and how they are adopted for Grid computing. He also discusses the advantages of using a graphical user interface over a command-line interface and presents a graphical workflow editor that enables users to compose sequences of computational tasks visually using a simple drag-and-drop interface. The final chapter explains how to deploy applications on a Grid. The Grid computing platform offers much more than simply running an application at a remote site. It also enables multiple geographically distributed computers to collectively obtain increased speed and fault tolerance. Illustrating this kind of resource discovery this practical text encompasses the varied and interconnected aspects of Grid computing including how to design a system infrastructure and Grid portal. Supplemental Web ResourcesThe author’s Web site offers various instructional resources including slides and links to software for programming assignments. Many of these assignments do not require access to a Grid platform. Instead the author provides step-by-step instructions for installing open-source software to deploy and test Web and Grid services a Grid computing workflow editor to design and test workflows and a Grid computing portal to deploy portlets. | Grid Computing Techniques and Applications

GBP 69.99
1

Linux The Textbook Second Edition

Linux The Textbook Second Edition

Choosen by BookAuthority as one of BookAuthority's Best Linux Mint Books of All TimeLinux: The Textbook Second Edition provides comprehensive coverage of the contemporary use of the Linux operating system for every level of student or practitioner from beginners to advanced users. The text clearly illustrates system-specific commands and features using Debian-family Debian Ubuntu and Linux Mint and RHEL-family CentOS and stresses universal commands and features that are critical to all Linux distributions. The second edition of the book includes extensive updates and new chapters on system administration for desktop stand-alone PCs and server-class computers; API for system programming including thread programming with pthreads; virtualization methodologies; and an extensive tutorial on systemd service management. Brand new online content on the CRC Press website includes an instructor’s workbook test bank and In-Chapter exercise solutions as well as full downloadable chapters on Python Version 3. 5 programming ZFS TC shell programming advanced system programming and more. An author-hosted GitHub website also features updates further references and errata. Features New or updated coverage of file system sorting regular expressions directory and file searching file compression and encryption shell scripting system programming client-server–based network programming thread programming with pthreads and system administration Extensive in-text pedagogy including chapter objectives student projects and basic and advanced student exercises for every chapter Expansive electronic downloads offer advanced content on Python ZFS TC shell scripting advanced system programming internetworking with Linux TCP/IP and many more topics all featured on the CRC Press website Downloadable test bank work book and solutions available for instructors on the CRC Press website Author-maintained GitHub repository provides other resources such as live links to further references updates and errata | Linux The Textbook Second Edition

GBP 38.99
1

Games Gambling and Probability An Introduction to Mathematics

Games Gambling and Probability An Introduction to Mathematics

Many experiments have shown the human brain generally has very serious problems dealing with probability and chance. A greater understanding of probability can help develop the intuition necessary to approach risk with the ability to make more informed (and better) decisions. The first four chapters offer the standard content for an introductory probability course albeit presented in a much different way and order. The chapters afterward include some discussion of different games different ideas that relate to the law of large numbers and many more mathematical topics not typically seen in such a book. The use of games is meant to make the book (and course) feel like fun! Since many of the early games discussed are casino games the study of those games along with an understanding of the material in later chapters should remind you that gambling is a bad idea; you should think of placing bets in a casino as paying for entertainment. Winning can obviously be a fun reward but should not ever be expected. Changes for the Second Edition: New chapter on Game Theory New chapter on Sports Mathematics The chapter on Blackjack which was Chapter 4 in the first edition appears later in the book. Reorganization has been done to improve the flow of topics and learning. New sections on Arkham Horror Uno and Scrabble have been added. Even more exercises were added! The goal for this textbook is to complement the inquiry-based learning movement. In my mind concepts and ideas will stick with the reader more when they are motivated in an interesting way. Here we use questions about various games (not just casino games) to motivate the mathematics and I would say that the writing emphasizes a just-in-time mathematics approach. Topics are presented mathematically as questions about the games themselves are posed. Table of Contents Preface1. Mathematics and Probability 2. Roulette and Craps: Expected Value 3. Counting: Poker Hands 4. More Dice: Counting and Combinations and Statistics 5. Game Theory: Poker Bluffing and Other Games 6. Probability/Stochastic Matrices: Board Game Movement 7. Sports Mathematics: Probability Meets Athletics 8. Blackjack: Previous Methods Revisited 9. A Mix of Other Games 10. Betting Systems: Can You Beat the System? 11. Potpourri: Assorted Adventures in Probability Appendices Tables Answers and Selected Solutions Bibliography Biography Dr. David G. Taylor is a professor of mathematics and an associate dean for academic affairs at Roanoke College in southwest Virginia. He attended Lebanon Valley College for his B. S. in computer science and mathematics and went to the University of Virginia for his Ph. D. While his graduate school focus was on studying infinite dimensional Lie algebras he started studying the mathematics of various games in order to have a more undergraduate-friendly research agenda. Work done with two Roanoke College students Heather Cook and Jonathan Marino appears in this book! Currently he owns over 100 different board games and enjoys using probability in his decision-making while playing most of those games. In his spare time he enjoys reading cooking coding playing his board games and spending time with his six-year-old dog Lilly. | Games Gambling and Probability An Introduction to Mathematics

GBP 82.99
1

Basic Matrix Algebra with Algorithms and Applications

Basic Matrix Algebra with Algorithms and Applications

Clear prose tight organization and a wealth of examples and computational techniques make Basic Matrix Algebra with Algorithms and Applications an outstanding introduction to linear algebra. The author designed this treatment specifically for freshman majors in mathematical subjects and upper-level students in natural resources the social sciences business or any discipline that eventually requires an understanding of linear models. With extreme pedagogical clarity that avoids abstraction wherever possible the author emphasizes minimal polynomials and their computation using a Krylov algorithm. The presentation is highly visual and relies heavily on work with a graphing calculator to allow readers to focus on concepts and techniques rather than on tedious arithmetic. Supporting materials including test preparation Maple worksheets are available for download from the Internet. This unassuming but insightful and remarkably original treatment is organized into bite-sized clearly stated objectives. It goes well beyond the LACSG recommendations for a first course while still implementing their philosophy and core material. Classroom tested with great success it prepares readers well for the more advanced studies their fields ultimately will require.

GBP 175.00
1

Introduction to Biological Networks

Introduction to Biological Networks

The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap Introduction to Biological Networks provides a thorough introduction to genomics-inspired network biology for physical scientists and biologists involved in interdisciplinary research. The book focuses on the concept of molecular and genetic interaction networks as a paradigm for interpreting the complexity of molecular biology at a genomic scale. The authors describe the experimental methods used to discover and test networks of interaction among biological molecules. They also present computational methods for predicting the interaction networks discuss general mechanisms of network formation and evolution and explore the application of network approaches to important problems in biology and medicine. With many examples throughout and clear explanations of key concepts this book is the first to offer a broad treatment of genomics-inspired network biology with sufficient mathematical and biological rigor. It gives readers a conceptual understanding of this burgeoning scientific field.

GBP 59.99
1

Linear Regression Models Applications in R

Linear Regression Models Applications in R

Research in social and behavioral sciences has benefited from linear regression models (LRMs) for decades to identify and understand the associations among a set of explanatory variables and an outcome variable. Linear Regression Models: Applications in R provides you with a comprehensive treatment of these models and indispensable guidance about how to estimate them using the R software environment. After furnishing some background material the author explains how to estimate simple and multiple LRMs in R including how to interpret their coefficients and understand their assumptions. Several chapters thoroughly describe these assumptions and explain how to determine whether they are satisfied and how to modify the regression model if they are not. The book also includes chapters on specifying the correct model adjusting for measurement error understanding the effects of influential observations and using the model with multilevel data. The concluding chapter presents an alternative model—logistic regression—designed for binary or two-category outcome variables. The book includes appendices that discuss data management and missing data and provides simulations in R to test model assumptions. Features Furnishes a thorough introduction and detailed information about the linear regression model including how to understand and interpret its results test assumptions and adapt the model when assumptions are not satisfied. Uses numerous graphs in R to illustrate the model’s results assumptions and other features. Does not assume a background in calculus or linear algebra rather an introductory statistics course and familiarity with elementary algebra are sufficient. Provides many examples using real-world datasets relevant to various academic disciplines. Fully integrates the R software environment in its numerous examples. The book is aimed primarily at advanced undergraduate and graduate students in social behavioral health sciences and related disciplines taking a first course in linear regression. It could also be used for self-study and would make an excellent reference for any researcher in these fields. The R code and detailed examples provided throughout the book equip the reader with an excellent set of tools for conducting research on numerous social and behavioral phenomena. John P. Hoffmann is a professor of sociology at Brigham Young University where he teaches research methods and applied statistics courses and conducts research on substance use and criminal behavior. | Linear Regression Models Applications in R

GBP 66.99
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Advanced Engineering Mathematics A Second Course with MatLab

Advanced Engineering Mathematics A Second Course with MatLab

Through four previous editions of Advanced Engineering Mathematics with MATLAB the author presented a wide variety of topics needed by today's engineers. The fifth edition of that book available now has been broken into two parts: topics currently needed in mathematics courses and a new stand-alone volume presenting topics not often included in these courses and consequently unknown to engineering students and many professionals. The overall structure of this new book consists of two parts: transform methods and random processes. Built upon a foundation of applied complex variables the first part covers advanced transform methods as well as z-transforms and Hilbert transforms-transforms of particular interest to systems communication and electrical engineers. This portion concludes with Green's function a powerful method of analyzing systems. The second portion presents random processes-processes that more accurately model physical and biological engineering. Of particular interest is the inclusion of stochastic calculus. The author continues to offer a wealth of examples and applications from the scientific and engineering literature a highlight of his previous books. As before theory is presented first then examples and then drill problems. Answers are given in the back of the book. This book is all about the future: The purpose of this book is not only to educate the present generation of engineers but also the next. The main strength is the text is written from an engineering perspective. The majority of my students are engineers. The physical examples are related to problems of interest to the engineering students. Lea Jenkins Clemson University | Advanced Engineering Mathematics A Second Course with MatLab

GBP 82.99
1

A Criminologist's Guide to R Crime by the Numbers

A Criminologist's Guide to R Crime by the Numbers

A Criminologist's Guide to R: Crime by the Numbers introduces the programming language R and covers the necessary skills to conduct quantitative research in criminology. By the end of this book a person without any prior programming experience can take raw crime data be able to clean it visualize the data present it using R Markdown and change it to a format ready for analysis. A Criminologist's Guide to R focuses on skills specifically for criminology such as spatial joins mapping and scraping data from PDFs however any social scientist looking for an introduction to R for data analysis will find this useful. Key Features: Introduction to RStudio including how to change user preference settings. Basic data exploration and cleaning – subsetting loading data regular expressions aggregating data. Graphing with ggplot2. How to make maps (hotspot maps choropleth maps interactive maps). Webscraping and PDF scraping. Project management – how to prepare for a project how to decide which projects to do best ways to collaborate with people how to store your code (using git) and how to test your code. | A Criminologist's Guide to R Crime by the Numbers

GBP 74.99
1

Polynomial Completeness in Algebraic Systems

Polynomial Completeness in Algebraic Systems

Boolean algebras have historically played a special role in the development of the theory of general or universal algebraic systems providing important links between algebra and analysis set theory mathematical logic and computer science. It is not surprising then that focusing on specific properties of Boolean algebras has lead to new directions in universal algebra. In the first unified study of polynomial completeness Polynomial Completeness in Algebraic Systems focuses on and systematically extends another specific property of Boolean algebras: the property of affine completeness. The authors present full proof that all affine complete varieties are congruence distributive and that they are finitely generated if and only if they can be presented using only a finite number of basic operations. In addition to these important findings the authors describe the different relationships between the properties of lattices of equivalence relations and the systems of functions compatible with them. An introductory chapter surveys the appropriate background material exercises in each chapter allow readers to test their understanding and open problems offer new research possibilities. Thus Polynomial Completeness in Algebraic Systems constitutes an accessible coherent presentation of this rich topic valuable to both researchers and graduate students in general algebraic systems.

GBP 59.99
1

Statistics in Toxicology Using R

Statistics in Toxicology Using R

The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas Statistics in Toxicology Using R explains the statistical analysis of selected experimental data in toxicology and presents assay-specific suggestions such as for the in vitro micronucleus assay. Mostly focusing on hypothesis testing the book covers standardized bioassays for chemicals drugs and environmental pollutants. It is organized according to selected toxicological assays including: Short-term repeated toxicity studiesLong-term carcinogenicity assays Studies on reproductive toxicity Mutagenicity assays Toxicokinetic studies The book also discusses proof of safety (particularly in ecotoxicological assays) toxicogenomics the analysis of interlaboratory studies and the modeling of dose-response relationships for risk assessment. For each toxicological problem the author describes the statistics involved matching data example R code and outcomes and their interpretation. This approach allows you to select a certain bioassay identify the specific data structure run the R code with the data example understand the test outcome and interpretation and replace the data set with your own data and run again.

GBP 44.99
1

An Advanced Course in Probability and Stochastic Processes

An Advanced Course in Probability and Stochastic Processes

An Advanced Course in Probability and Stochastic Processes provides a modern and rigorous treatment of probability theory and stochastic processes at an upper undergraduate and graduate level. Starting with the foundations of measure theory this book introduces the key concepts of probability theory in an accessible way providing full proofs and extensive examples and illustrations. Fundamental stochastic processes such as Gaussian processes Poisson random measures Lévy processes Markov processes and Itô processes are presented and explored in considerable depth showcasing their many interconnections. Special attention is paid to martingales and the Wiener process and their central role in the treatment of stochastic integrals and stochastic calculus. This book includes many exercises designed to test and challenge the reader and expand their skillset. An Advanced Course in Probability and Stochastic Processes is meant for students and researchers who have a solid mathematical background and who have had prior exposure to elementary probability and stochastic processes. Key Features: Focus on mathematical understanding Rigorous and self-contained Accessible and comprehensive High-quality illustrations Includes essential simulation algorithms Extensive list of exercises and worked-out examples Elegant and consistent notation

GBP 89.99
1