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Food Allergy Molecular and Clinical Practice

Food Allergy Molecular and Clinical Practice

Food allergy is an adverse immunological reaction to allergens present in food. Up to 4% adults and 8% children are affected by food allergy. The increase in allergic diseases to food has led to the need for better diagnostics and more effective therapeutic approaches. This book describes the molecular biology and immunology of major food allergens from laboratory based science to clinical immunology encompassing novel characterisation and quantification methods the application of recombinant food allergens in molecular diagnosis and the development of novel therapeutics. This book is the ideal reference tool for researchers students and allergy clinicians to accurately diagnose and manage food allergies. | Food Allergy Molecular and Clinical Practice

GBP 44.99
1

Embedded Software System Testing Automatic Testing Solution Based on Formal Method

Embedded Software System Testing Automatic Testing Solution Based on Formal Method

This book introduces embedded software engineering and management methods proposing the relevant testing theory and techniques that promise the final realization of automated testing of embedded systems. The quality and reliability of embedded systems have become a great concern faced with the rising demands for the complexity and scale of system hardware and software. The authors propose and expound on the testing theory and techniques of embedded software systems and relevant environment construction technologies providing effective solutions for the automated testing of embedded systems. Through analyzing typical testing examples of the complex embedded software systems the authors verify the effectiveness of the theories technologies and methods proposed in the book. In combining the fundamental theory and technology and practical solutions this book will appeal to researchers and students studying computer science software engineering and embedded systems as well as professionals and practitioners engaged in the development verification and maintenance of embedded systems in the military and civilian fields. | Embedded Software System Testing Automatic Testing Solution Based on Formal Method

GBP 77.99
1

Textbook of Allergy for the Clinician

Textbook of Allergy for the Clinician

This is the second and updated version of the Textbook of Allergy for the Clinician. It is a unique book in the field of allergy. The uniqueness lies in the international character of the book with contributors representing both the East and West. This book represents the diversity of issues affecting patients in the specialty of allergy asthma & immunology. There is some discussion of the basic mechanisms involved and extensive elaboration for the clinicians. This book will appeal to medical students residents and fellows undergoing training as well as consultants in academic and clinical practice settings. The color plates especially in the section on Aerobiology will help in the interaction between the patient and consultant in identifying the plant or flora which is the causative factor. The differences and similarities between the Eastern and Western approaches in the practice of the specialty are being addressed for the first time in a book.

GBP 66.99
1

Software Testing A Craftsman’s Approach Fifth Edition

Software Testing A Craftsman’s Approach Fifth Edition

This updated and reorganized Fifth edition of Software Testing: A Craftsman's Approach continues to be a valuable reference for software testers developers and engineers by applying the strong mathematics content of previous editions to a coherent treatment of software testing. Responding to instructor and student survey input the authors have streamlined chapters and examples. The Fifth Edition: Has a new chapter on feature interaction testing that explores the feature interaction problem and explains how to reduce tests Uses Java instead of pseudo-code for all examples including structured and object-oriented ones Presents model-based development and provides an explanation of how to conduct testing within model-based development environments Explains testing in waterfall iterative and agile software development projects Explores test-driven development reexamines all-pairs testing and explains the four contexts of software testing Thoroughly revised and updated Software Testing: A Craftsman’s Approach Fifth Edition is sure to become a standard reference for those who need to stay up to date with evolving technologies in software testing. | Software Testing A Craftsman’s Approach Fifth Edition

GBP 39.95
1

Load Testing of Bridges: Two Volume Set

Load Testing of Bridges: Two Volume Set

Load Testing of Bridges featuring contributions from almost fifty authors from around the world across two interrelated volumes deals with the practical aspects the scientific developments and the international views on the topic of load testing of bridges. Volume 12 Load Testing of Bridges: Current practice and Diagnostic Load Testing starts with a background to bridge load testing including the historical perspectives and evolutions and the current codes and guidelines that are governing in countries around the world. The second part of the book deals with preparation execution and post-processing of load tests on bridges. The third part focuses on diagnostic load testing of bridges. Volume 13 Load Testing of Bridges: Proof Load Testing and the Future of Load Testing focuses first on proof load testing of bridges. It discusses the specific aspects of proof load testing during the preparation execution and post-processing of such a test (Part 1). The second part covers the testing of buildings. The third part discusses novel ideas regarding measurement techniques used for load testing. Methods using non-contact sensors such as photography- and video-based measurement techniques are discussed. The fourth part discusses load testing in the framework of reliability-based decision-making and in the framework of a bridge management program. The final part of the book summarizes the knowledge presented across the two volumes as well as the remaining open questions for research and provides practical recommendations for engineers carrying out load tests. This work will be of interest to researchers and academics in the field of civil/structural engineering practicing engineers and road authorities worldwide. | Load Testing of Bridges: Two Volume Set

GBP 44.99
1

Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

Automated Software Testing with Cypress

Automated Software Testing with Cypress

Unit Integration Testing (UIT) had been a challenge because there was no tool that could help in XHR programming and unit integration validations in an efficient way until Cypress arrived. Cypress started releasing versions in 2015 and became popular in 2018 with version 2. 0. 0. This book explores Cypress scripts that help implement ‘shift left testing’ which is a dream come true for many software testers. Shift left occurs in the majority of testing projects but could not be implemented fully because tools were unavailable and knowledge was lacking about the possibilities of testing early in the life cycle. Shift left is a key testing strategy to help testing teams focus less on defect identifications and more on developing practices to prevent defects. Cypress scripts can help front-end developers and quality engineers to work together to find defects soon after web components are built. These components can be tested immediately after they are built with Cypress Test Driven Development (TDD) scripts. Thus defects can be fixed straight away during the development stage. Testing teams do not have to worry about finding these same defects in a later development stage because Cypress tests keep verifying components in the later stages. Defect fixing has become much cheaper with Cypress than when other tools are used. The book also covers Behaviour Driven Development (BDD)-based Gherkin scripts and the Cypress Cucumber preprocessor which can improve test scenario coverage. Automated Software Testing with Cypress is written to fulfil the BDD and TDD needs of testing teams. Two distinct open source repositories are provided in Github to help start running Cypress tests in no time!

GBP 38.99
1

Sport and Exercise Physiology Testing Guidelines: Volume I - Sport Testing The British Association of Sport and Exercise Sciences Guide

Sport and Exercise Physiology Testing Guidelines: Volume I - Sport Testing The British Association of Sport and Exercise Sciences Guide

Since its first published edition more than 30 years ago the BASES (British Association of Sport and Exercise Sciences) Physiological Testing Guidelines have represented the leading knowledge base of current testing methodology for sport and exercise scientists. Sport and exercise physiologists conduct physiological assessments that have proven validity and reliability both in laboratory and sport-specific contexts. A wide variety of test protocols have been developed adapted and refined to support athletes of all abilities reach their full potential. This book is a comprehensive guide to these protocols and to the key issues relating to physiological testing. With contributions from leading specialist sport physiologists and covering a wide range of mainstream sports in terms of ethical practical and methodological issues this volume represents an essential resource for sport-specific exercise testing in both research and applied settings. This new edition draws on the authors’ experience of supporting athletes from many sports through several Olympic cycles to achieve world leading performances. While drawing on previous editions it is presented in a revised format matching the sport groupings used in elite sport support within the UK sport institutes. Building on the underpinning general procedures these specific chapters are supported by appropriate up-to-date case studies in the supporting web resources. | Sport and Exercise Physiology Testing Guidelines: Volume I - Sport Testing The British Association of Sport and Exercise Sciences Guide

GBP 48.99
1

Psychological Assessment and Testing A Clinician's Guide

Psychological Assessment and Testing A Clinician's Guide

Expanding upon and updating the first edition this comprehensive guide instructs readers on how to effectively conduct psychological assessment and testing in their practice efficiently advancing a case from the initial referral and clinical interview through the testing process and leading to informed diagnosis and treatment recommendations. This second edition incorporates updated editions of all major tests pertinent revisions from the DSM-5 more in-depth analysis of testing topics and coverage of new constructs that are the targets of psychological testing relevant to outpatient mental health practice. Readers will learn about the fundamentals of assessment testing and psychological measurement the complete process of psychological testing using a broad range of major tests supplemented by interpretive flowcharts and case examples. . Downloadable practice and report forms along with data tables with pre-drafted interpretive excerpts for all tests are also available for immediate use in clinical practice. Psychologists in both practice and training will come away with the tools and knowledge needed to successfully conduct psychological assessment and testing within the contemporary mental health field. | Psychological Assessment and Testing A Clinician's Guide

GBP 69.99
1

Miniaturized Testing of Engineering Materials

Miniaturized Testing of Engineering Materials

This book is a comprehensive overview of methods of characterizing the mechanical properties of engineering materials using specimen sizes in the micro-scale regime (0. 3-5. 0 mm). A range of issues associated with miniature specimen testing like correlation methodologies for data transferability between different specimen sizes use of numerical simulation/analysis for data inversion application to actual structures using scooped out samples or by in-situ testing and more importantly developing a common code of practice are discussed and presented in a concise manner. | Miniaturized Testing of Engineering Materials

GBP 44.99
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Fully up-to-date with the relevant parts of the 17th Edition IET Wiring Regulations: Amendment 3 and the 2012 Code of Practice Provides all the required information on portable appliance testing in a user-friendly manner Expert advice from an engineering training consultant supported with colour diagrams examples and tables The Electricity at Work Regulations 1989 requires any electrical system to be constructed maintained and used in such a manner as to prevent danger. This means that inspection and testing of systems including portable appliances is needed in order to determine if maintenance is required. This book explains in clear language what needs to be done and includes expert advice on legislation as well as actual testing. The book contains an appendix providing the electrical fundamentals needed by non-specialists and also has sample questions (with answers) for the CandG 2377 exam. It is also an ideal revision guide for the non-specialist such as maintenance staff and caretakers who carry out these tasks part-time alongside their many other duties. | PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

GBP 175.00
1

Sport and Exercise Physiology Testing Guidelines: Volume II - Exercise and Clinical Testing The British Association of Sport and Exercise Sc

Sport and Exercise Physiology Testing Guidelines: Volume II - Exercise and Clinical Testing The British Association of Sport and Exercise Sc

Since its first published edition more than 30 years ago the BASES (British Association of Sport and Exercise Sciences) Physiological Testing Guidelines have represented the leading knowledge base of current testing methodology for sport and exercise scientists. Sport and exercise physiologists conduct physiological assessments that have proven validity and reliability both in laboratory and sport-specific contexts. A wide variety of test protocols have been developed adapted and refined to support athletes of all abilities reach their full potential. This book is a comprehensive guide to these protocols and to the key issues relating to physiological testing. With contributions from leading specialist sport physiologists and covering a wide range of mainstream sports in terms of ethical practical and methodological issues this volume represents an essential resource for sport-specific exercise testing in both research and applied settings. This new edition draws on the authors’ experience of supporting athletes from many sports through several Olympic cycles to achieve world leading performances. While drawing on previous editions it is presented in a revised format matching the sport groupings used in elite sport support within the UK sport institutes. Building on the underpinning general procedures these specific chapters are supported by appropriate up-to-date case studies in the supporting web resources. | Sport and Exercise Physiology Testing Guidelines: Volume II - Exercise and Clinical Testing The British Association of Sport and Exercise Sc

GBP 48.99
1

The Routledge Handbook of Language Testing

The Routledge Handbook of Language Testing

This second edition of The Routledge Handbook of Language Testing provides an updated and comprehensive account of the area of language testing and assessment. The volume brings together 35 authoritative articles divided into ten sections written by 51 leading specialists from around the world. There are five entirely new chapters covering the four skills: reading writing listening and speaking as well as a new entry on corpus linguistics and language testing. The remaining 30 chapters have been revised often extensively or entirely rewritten with new authorship teams at the helm reflecting new generations of expertise in the field. With a dedicated section on technology in language testing reflecting current trends in the field the Handbook also includes an extended epilogue written by Harding and Fulcher contemplating what has changed between the first and second editions and charting a trajectory for the field of language testing and assessment. Providing a basis for discussion project work and the design of both language tests themselves and related validation research this Handbook represents an invaluable resource for students researchers and practitioners working in language testing and assessment and the wider field of language education.

GBP 205.00
1

Monographs in Contact Allergy Volume 1 Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2)

Monographs in Contact Allergy Volume 1 Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2)

Monographs in Contact Allergy Volume 1: Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2) is the first 2-part volume in an exciting series on contact allergy. It presents over 500 natural or synthetic chemicals and compounds which have caused allergic contact dermatitis in cosmetic products. Included here are INCI names synonyms description/definition CAS and EU numbers chemical class function in cosmetics molecular formula structural formula and advice on patch tests. A full literature review is given of patch testing in patients case reports of cosmetic allergic contact dermatitis irritant contact dermatitis photosensitivity immediate contact reactions and systemic side effects. This text is suitable for anyone with an interest in contact allergy from university students to professionals and all readers will find this informative and detailed series an invaluable resource. Key Features: Monographs of all known non-fragrance chemicals and substances which have caused allergic contact dermatitis from their presence in cosmetic products Provides lists of all functional groups (such as antioxidants preservatives artificial nail building emollients hair dyeing hair colorants) in both the EU and US formats and all chemicals in these groups which have caused cosmetic allergy Presents an alphabetical list of all synonyms indicating their INCI names Reported cross-reactions pseudo-cross-reactions and co-reactions patch test sensitization and presence in cosmetic products (including data from FDA’s Voluntary Cosmetic Registration Program) and chemical analyses are discussed Covers an extensive amount of information to benefit dermatologists allergists and non-medical professionals involved with the research development and marketing of cosmetic products | Monographs in Contact Allergy Volume 1 Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2)

GBP 66.99
1

Thermal-Aware Testing of Digital VLSI Circuits and Systems

Thermal-Aware Testing of Digital VLSI Circuits and Systems

This book aims to highlight the research activities in the domain of thermal-aware testing. Thermal-aware testing can be employed both at circuit level and at system levelDescribes range of algorithms for addressing thermal-aware test issue presents comparison of temperature reduction with power-aware techniques and include results on benchmark circuits and systems for different techniquesThis book will be suitable for researchers working on power- and thermal-aware design and the testing of digital VLSI chips | Thermal-Aware Testing of Digital VLSI Circuits and Systems

GBP 18.99
1

Assessment and Testing An Introduction

Assessment and Testing An Introduction

Originally published in 1972 there were many ‘classics’ dealing with assessment and testing on the market at the time but most of these left the inexperienced reader bewildered in the early stages because of their size and insufficient explanation of the many technical terms used. There were a distinct lack of books which gave students in Colleges of Education dealing with psychology for the first time a simple explanation of basic terms in assessment and testing and which introduced them briefly to the different types of tests available. Assessment and Testing aimed to fill this large gap. It looks at such key psychological terms as ‘sample’ ‘objectivity’ ‘subjectivity’ and such basic statistical terms such as ‘mean’ ‘standard deviation’ and ‘normal curve of distribution’. Because it assumes that the reader has no knowledge of such terms it gives careful and simply illustrated explanations of each. In the same way in simple language with any technical terms explained and illustrated it explains intelligence and personality tests questionnaires sociometric measures projection techniques and other areas of assessment and testing which every practising teacher will meet. The book aims to be essentially practical. It is appreciated all the time that the readers are those who will teach children. It is designed to provide a solid foundation upon which the reader can build later to augment his own experience of identifying children’s particular needs. | Assessment and Testing An Introduction

GBP 29.99
1

Sequential Analysis Hypothesis Testing and Changepoint Detection

Sequential Analysis Hypothesis Testing and Changepoint Detection

Sequential Analysis: Hypothesis Testing and Changepoint Detection systematically develops the theory of sequential hypothesis testing and quickest changepoint detection. It also describes important applications in which theoretical results can be used efficiently. The book reviews recent accomplishments in hypothesis testing and changepoint detection both in decision-theoretic (Bayesian) and non-decision-theoretic (non-Bayesian) contexts. The authors not only emphasize traditional binary hypotheses but also substantially more difficult multiple decision problems. They address scenarios with simple hypotheses and more realistic cases of two and finitely many composite hypotheses. The book primarily focuses on practical discrete-time models with certain continuous-time models also examined when general results can be obtained very similarly in both cases. It treats both conventional i. i. d. and general non-i. i. d. stochastic models in detail including Markov hidden Markov state-space regression and autoregression models. Rigorous proofs are given for the most important results. Written by leading authorities in the field this book covers the theoretical developments and applications of sequential hypothesis testing and sequential quickest changepoint detection in a wide range of engineering and environmental domains. It explains how the theoretical aspects influence the hypothesis testing and changepoint detection problems as well as the design of algorithms. | Sequential Analysis Hypothesis Testing and Changepoint Detection

GBP 44.99
1

Unequal By Design High-Stakes Testing and the Standardization of Inequality

Unequal By Design High-Stakes Testing and the Standardization of Inequality

This new edition of Unequal By Design: High-Stakes Testing and the Standardization of Inequality critically examines the deep and enduring problems within systems of education in the U. S. in order to illuminate what is really at stake for students teachers and communities negatively affected by such testing. Updates to the new edition include new chapters that focus on: the role of schools and standardized testing in reproducing social cultural and economic inequalities; the way high-stakes testing is used to advance neoliberal market-based educational schemes that ultimately concentrate wealth and power among elites; how standardized testing became the dominant tool within our educational systems; the numerous technical and ideological problems with using standardized tests to evaluate students teachers and schools; the role that high-stakes testing plays in the maintenance of white supremacy; and how school communities have resisted high-stakes testing and used better assessments of student learning. Parents teachers university students and scholars will find Unequal By Design useful for gaining a broad critical understanding of the issues surrounding our over-reliance on high-stakes standardized testing in the U. S. through up-to-date research on testing historical and contemporary examples of the struggles over such tests and information about how testing has fostered the privatization of public education in the U. S. | Unequal By Design High-Stakes Testing and the Standardization of Inequality

GBP 38.99
1

Get Qualified: Inspection and Testing

Get Qualified: Inspection and Testing

The Get Qualified series provides clear and concise guidance for people looking to work within the electrical industry. This book outlines why the inspection and testing of electrical installations is important and what qualifications are required in order to test inspect and certify. All you need to know about the subject of inspection is covered in detail making this book the ideal guide for those who are new to the subject and experienced professionals alike. There are also sections on exam preparation revision exercises and sample questions. | Get Qualified: Inspection and Testing

GBP 46.99
1

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook: Transients Control Principles Design and Testing presents a practical up-to-date treatment of intricate issues with induction machines (IM) required for design and testing in both rather constant- and variable-speed (with power electronics) drives. It contains ready-to-use industrial design and testing knowledge with numerous case studies to facilitate a thorough assimilation of new knowledge. Individual Chapters 1 through 14 discuss in detail the following: Three- and multiphase IM transients Single-phase source IM transients Super-high-frequency models and behavior of IM Motor specifications and design principles IM design below 100 kW and constant V1 and f1 IM design above 100 kW and constant V1 and f1 IM design principles for variable speed Optimization design Single-phase IM design Three-phase IM generators Single-phase IM generators Linear induction motors Testing of three-phase IMs Single-phase IM testing Fully revised and amply updated to add the new knowledge of the last decade this third edition includes special sections on Multiphase IM models for transients Doubly fed IMs models for transients Cage-rotor synchronized reluctance motors Cage-rotor PM synchronous motor Transient operation of self-excited induction generator Brushless doubly fed induction motor/generators Doubly fed induction generators with D. C. output Linear induction motor control with end effect Recent trends in IM testing with power electronics Cage-PM rotor line-start IM testing Linear induction motor (LIM) testing This up-to-date book discusses in detail the transients control principles and design and testing of various IMs for line-start and variable-speed applications in various topologies with numerous case studies. It will be of direct assistance to academia and industry in conceiving designing fabricating and testing IMs (for the future) of various industries from home appliances through robotics e-transport and renewable energy conversion. | Induction Machines Handbook Transients Control Principles Design and Testing

GBP 140.00
1

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials: Theoretical Foundations explores the mathematical foundations and emerging applications of this testing process which is based on elastic wave propagation in isotropic and anisotropic solids. In covering ultrasonic nondestructive testing methods the book emphasizes the engineering point of view yet it relies on the physics and mathematics aspects involved in elastic wave propagation theory. As a result this resource becomes a missing link in the literature by combining coverage of the theoretical aspects of testing and providing intuitive assessments of numerous standard problems to illustrate fundamental assertions. Content includes a brief description of the theory of acoustic and electromagnetic fields to underline the similarities and differences as compared to elastodynamics. It also covers vector algebra and analysis elastic plane and Rayleigh surface waves and ultrasonic beams as well as transducer radiation inverse scattering and ultrasonic nondestructive imaging. Includes numerical computations to explain wave propagation phenomena and compare results of analytical formulations Although ultrasonic nondestructive testing can often be roughly understood in terms of plane waves and beams this book addresses the key issues of transducer radiation and defect scattering and imaging respectively. The authors physically formulate point source synthesis and in mathematical terms they use representation integrals with Green functions always including intuitive interpretations with mathematical evaluations. Replacing cumbersome index notation with a coordinate-free version this reference offers step-by-step documentation of relevant tensorial elastodynamic cases involving isotropic and anisotropic materials. It provides all necessary mathematical tools readers require to understand the mathematical and physical basis for ultrasonic nondestructive testing. | Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

GBP 94.99
1

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials: Introduction and Laboratory Testing discusses the properties characterization procedures and analysis techniques of primary civil engineering materials. It presents the latest design considerations and uses of engineering materials as well as theories for fully understanding them through numerous worked mathematical examples. The book also includes important laboratory tests which are clearly described in a step-by-step manner and further illustrated by high-quality figures. Also analysis equations and their applications are presented with appropriate examples and relevant practice problems including Fundamentals of Engineering (FE) styled questions as well those found on the American Concrete Institute (ACI) Concrete Field Testing Technician - Grade I certification exam. Features: Includes numerous worked examples to illustrate the theories presented Presents Fundamentals of Engineering (FE) examination sample questions in each chapter Reviews the ACI Concrete Field Testing Technician - Grade I certification exam Utilizes the latest laboratory testing standards and practices Includes additional resources for instructors teaching related courses This book is intended for students in civil engineering construction engineering civil engineering technology construction management engineering technology and construction management programs. | Civil Engineering Materials Introduction and Laboratory Testing

GBP 99.99
1

Mechanical Wear Fundamentals and Testing Revised and Expanded

Mechanical Wear Fundamentals and Testing Revised and Expanded

Written by a tribological expert with more than thirty years of experience in the field Mechanical Wear Fundamentals and Testing Second Edition compiles an extensive range of graphs tables micrographs and drawings to illustrate wear friction and lubrication behavior in modern engineering applications. The author promotes a clear understanding of wear testing methodologies for avoidance and resolution of deterioration and weakening in specific engineering designs. Comprehensively describes more than 20 different phenomenological wear tests and over 10 operational wear tests | Mechanical Wear Fundamentals and Testing Revised and Expanded

GBP 59.99
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Multiple Testing Problems in Pharmaceutical Statistics

Multiple Testing Problems in Pharmaceutical Statistics

Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians scientists and clinicians from the pharmaceutical industry academia and regulatory agencies Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter the expert contributors describe important multiplicity problems encountered in pre-clinical and clinical trial settings. The book begins with a broad introduction from a regulatory perspective to different types of multiplicity problems that commonly arise in confirmatory controlled clinical trials before giving an overview of the concepts principles and procedures of multiple testing. It then presents statistical methods for analyzing clinical dose response studies that compare several dose levels with a control as well as statistical methods for analyzing multiple endpoints in clinical trials. After covering gatekeeping procedures for testing hierarchically ordered hypotheses the book discusses statistical approaches for the design and analysis of adaptive designs and related confirmatory hypothesis testing problems. The final chapter focuses on the design of pharmacogenomic studies based on established statistical principles. It also describes the analysis of data collected in these studies taking into account the numerous multiplicity issues that occur. This volume explains how to solve critical issues in multiple testing encountered in pre-clinical and clinical trial applications. It presents the necessary statistical methodology along with examples and software code to show how to use the methods in practice.

GBP 42.99
1