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Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

Handbook of Alternative Data in Finance Volume I

Handbook of Alternative Data in Finance Volume I

Handbook of Alternative Data in Finance Volume I motivates and challenges the reader to explore and apply Alternative Data in finance. The book provides a robust and in-depth overview of Alternative Data including its definition characteristics difference from conventional data categories of Alternative Data Alternative Data providers and more. The book also offers a rigorous and detailed exploration of process application and delivery that should be practically useful to researchers and practitioners alike. Features Includes cutting edge applications in machine learning fintech and more Suitable for professional quantitative analysts and as a resource for postgraduates and researchers in financial mathematics Features chapters from many leading researchers and practitioners

GBP 140.00
1

Alternative Proteins Safety and Food Security Considerations

Alternative Proteins Safety and Food Security Considerations

In the last decade there has been substantial research dedicated towards prospecting physiochemical nutritional and health properties of novel protein sources. In addition to being driven by predictions of increased population and lack of a parallel increase in traditional protein sources main drivers for the rise in novel proteins/ novel foods research activities is linked to significant changes in young consumers’ attitudes toward red meat consumption and their interest in new alternative protein products. Alternative Proteins: Safety and Food Security Considerations presents up-to-date information on alternative proteins from non-meat sources and examines their nutritional and functional roles as food sources and ingredients. Emphasis is placed on the safety of these novel proteins and an evaluation of their potential contribution to food security. Motivations for novel proteins and restrictions for their use are also discussed. Key Features: Explains potential improvements to alternative proteins through the employment of novel processing techniques. Contains the first review on keratin as an alternative protein source. Explores first comprehensive evaluation of the religious aspects of novel proteins. Describes methods for the detection and evaluation of health hazards. Discusses guidelines regulatory issues and recommendations for food safety Additionally this book covers fundamental and recent developments in the production of alternative proteins and examines safety and consumer acceptability wherever information is available. The sources and processing options for alternative proteins and their impact on final product characteristics are also covered. A collective contribution from international researchers who are active in their field of research and have made significant contributions to the the food sciences this book is beneficial to any researcher interested in the the food science and safety of alternative proteins. | Alternative Proteins Safety and Food Security Considerations

GBP 170.00
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Fully up-to-date with the relevant parts of the 17th Edition IET Wiring Regulations: Amendment 3 and the 2012 Code of Practice Provides all the required information on portable appliance testing in a user-friendly manner Expert advice from an engineering training consultant supported with colour diagrams examples and tables The Electricity at Work Regulations 1989 requires any electrical system to be constructed maintained and used in such a manner as to prevent danger. This means that inspection and testing of systems including portable appliances is needed in order to determine if maintenance is required. This book explains in clear language what needs to be done and includes expert advice on legislation as well as actual testing. The book contains an appendix providing the electrical fundamentals needed by non-specialists and also has sample questions (with answers) for the CandG 2377 exam. It is also an ideal revision guide for the non-specialist such as maintenance staff and caretakers who carry out these tasks part-time alongside their many other duties. | PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

GBP 175.00
1

Alternative Learning Environments

Alternative Learning Environments

Originally published in 1974 this volume presents viable alternatives to traditional attitudes and practices in environmental design and education. It contains 29 selections that reflect the thought and actions of leaders from many diverse disciplines and professions. Architects landscape architects urban planners teachers and administrators psychologists and social theorists address themselves to controversial and important issues facing our post-industrial society. The range of subjects explored in the volume is far-reaching: Environmental education in which the art of planning and designing itself becomes the curriculum Advocacy planning and community participation in both educational and design decision making Alternative educational institutions ranging from community-centered schools and mobile schools to non-school learning networks that distribute the learning activity throughout the fabric of the city and the lifetime of the learner New developments in systematic design methods and evaluation research that promise to make the design process more public and responsive to the user-client | Alternative Learning Environments

GBP 90.00
1

X-ESC LED 3 Hour Maintained Self Testing Curved Exit Sign

X-ESC LED 3 Hour Maintained Self Testing Curved Exit Sign

X-ESC LED 3 Hour Maintained Self Testing Curved Exit SignThe X-ESC Light is an attractively designed wall mounted emergency escape route sign. The convex front and perforated down light section make for an eye-catching alternative. With additional self-testing features to ensure that routine monthly and yearly tests are never missed.Comprising a white stove-enamelled zintec-coated sheet steel base and fitted with a self-extinguishing legend panel the ESS Light is designed for use on escape routes and final exits. It conforms to the 850C hot-wire test as defined by ICEL. The X-ESC Light has a 20mm cable knockout to the back. The X-ESC can be fitted with many different legends. With flexibility in mind theres a comprehensive choice of alternative finishes including any British Standard or RAL colour.Key FeaturesBright white LED light sourceIP20 interior useDual operating unitChrome and brass options availableDown light facilityRange of ISO 70102011 legends available30 M viewing distance

GBP 130.75
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway

<p>Experience ultimate comfort and allergy protection with the Ever range from Home Done. Our Simply Sleep Anti Allergy Microfibre Duvet is perfect for those with allergies, offering a luxurious feel 'Just like Down' with premium filling for warmth and comfort. The duvet is treated to be anti-allergy, featuring a 233 thread count 100% cotton percale piped case for pure luxury. Its carefully constructed baffle box stitching keeps the luxury filling evenly spaced, preventing cold patches and lumpy areas while allowing for proper aeration. Available in 10.5 Tog and four sizes: Single, Double, King, and Super King, in a classic white color.</p>

GBP 113.19
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - Single Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - Single Size - Galvin and Galloway

<p>Experience ultimate comfort and allergy protection with the Ever range from Home Done. Our Simply Sleep Anti Allergy Microfibre Duvet is perfect for those with allergies, offering a luxurious feel 'Just like Down' with premium filling for warmth and comfort. The duvet is treated to be anti-allergy, featuring a 233 thread count 100% cotton percale piped case for pure luxury. Its carefully constructed baffle box stitching keeps the luxury filling evenly spaced, preventing cold patches and lumpy areas while allowing for proper aeration. Available in 10.5 Tog and four sizes: Single, Double, King, and Super King, in a classic white color.</p>

GBP 88.89
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - Super King Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - Super King Size - Galvin and Galloway

<p>Experience ultimate comfort and allergy protection with the Ever range from Home Done. Our Simply Sleep Anti Allergy Microfibre Duvet is perfect for those with allergies, offering a luxurious feel 'Just like Down' with premium filling for warmth and comfort. The duvet is treated to be anti-allergy, featuring a 233 thread count 100% cotton percale piped case for pure luxury. Its carefully constructed baffle box stitching keeps the luxury filling evenly spaced, preventing cold patches and lumpy areas while allowing for proper aeration. Available in 10.5 Tog and four sizes: Single, Double, King, and Super King, in a classic white color.</p>

GBP 113.19
1

Institutionalization and Alternative Futures

Institutionalization and Alternative Futures

No one wants to put an aging relative in a home. But very few people have an understanding of the issues involved and options available for an older person who needs outside care. This important book offers a variety of new insights into ways of maximizing choice independence and well-being and minimizing the emotional stunting often associated with institutionalization. Both imaginative institutional programs and such alternatives as community maintenance are examined. | Institutionalization and Alternative Futures

GBP 120.00
1

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook: Transients Control Principles Design and Testing presents a practical up-to-date treatment of intricate issues with induction machines (IM) required for design and testing in both rather constant- and variable-speed (with power electronics) drives. It contains ready-to-use industrial design and testing knowledge with numerous case studies to facilitate a thorough assimilation of new knowledge. Individual Chapters 1 through 14 discuss in detail the following: Three- and multiphase IM transients Single-phase source IM transients Super-high-frequency models and behavior of IM Motor specifications and design principles IM design below 100 kW and constant V1 and f1 IM design above 100 kW and constant V1 and f1 IM design principles for variable speed Optimization design Single-phase IM design Three-phase IM generators Single-phase IM generators Linear induction motors Testing of three-phase IMs Single-phase IM testing Fully revised and amply updated to add the new knowledge of the last decade this third edition includes special sections on Multiphase IM models for transients Doubly fed IMs models for transients Cage-rotor synchronized reluctance motors Cage-rotor PM synchronous motor Transient operation of self-excited induction generator Brushless doubly fed induction motor/generators Doubly fed induction generators with D. C. output Linear induction motor control with end effect Recent trends in IM testing with power electronics Cage-PM rotor line-start IM testing Linear induction motor (LIM) testing This up-to-date book discusses in detail the transients control principles and design and testing of various IMs for line-start and variable-speed applications in various topologies with numerous case studies. It will be of direct assistance to academia and industry in conceiving designing fabricating and testing IMs (for the future) of various industries from home appliances through robotics e-transport and renewable energy conversion. | Induction Machines Handbook Transients Control Principles Design and Testing

GBP 140.00
1

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials: Theoretical Foundations explores the mathematical foundations and emerging applications of this testing process which is based on elastic wave propagation in isotropic and anisotropic solids. In covering ultrasonic nondestructive testing methods the book emphasizes the engineering point of view yet it relies on the physics and mathematics aspects involved in elastic wave propagation theory. As a result this resource becomes a missing link in the literature by combining coverage of the theoretical aspects of testing and providing intuitive assessments of numerous standard problems to illustrate fundamental assertions. Content includes a brief description of the theory of acoustic and electromagnetic fields to underline the similarities and differences as compared to elastodynamics. It also covers vector algebra and analysis elastic plane and Rayleigh surface waves and ultrasonic beams as well as transducer radiation inverse scattering and ultrasonic nondestructive imaging. Includes numerical computations to explain wave propagation phenomena and compare results of analytical formulations Although ultrasonic nondestructive testing can often be roughly understood in terms of plane waves and beams this book addresses the key issues of transducer radiation and defect scattering and imaging respectively. The authors physically formulate point source synthesis and in mathematical terms they use representation integrals with Green functions always including intuitive interpretations with mathematical evaluations. Replacing cumbersome index notation with a coordinate-free version this reference offers step-by-step documentation of relevant tensorial elastodynamic cases involving isotropic and anisotropic materials. It provides all necessary mathematical tools readers require to understand the mathematical and physical basis for ultrasonic nondestructive testing. | Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

GBP 94.99
1