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Thermal-Aware Testing of Digital VLSI Circuits and Systems

The Pocket Mentor for Video Game Testing

Multiple Testing Problems in Pharmaceutical Statistics

Multiple Testing Problems in Pharmaceutical Statistics

Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians scientists and clinicians from the pharmaceutical industry academia and regulatory agencies Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter the expert contributors describe important multiplicity problems encountered in pre-clinical and clinical trial settings. The book begins with a broad introduction from a regulatory perspective to different types of multiplicity problems that commonly arise in confirmatory controlled clinical trials before giving an overview of the concepts principles and procedures of multiple testing. It then presents statistical methods for analyzing clinical dose response studies that compare several dose levels with a control as well as statistical methods for analyzing multiple endpoints in clinical trials. After covering gatekeeping procedures for testing hierarchically ordered hypotheses the book discusses statistical approaches for the design and analysis of adaptive designs and related confirmatory hypothesis testing problems. The final chapter focuses on the design of pharmacogenomic studies based on established statistical principles. It also describes the analysis of data collected in these studies taking into account the numerous multiplicity issues that occur. This volume explains how to solve critical issues in multiple testing encountered in pre-clinical and clinical trial applications. It presents the necessary statistical methodology along with examples and software code to show how to use the methods in practice.

GBP 42.99
1

Ransomware Penetration Testing and Contingency Planning

Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs: From Science to Scene Second Edition is designed to help canine handlers detectives death investigators crime scene personnel (including forensic laboratory personnel technicians and supervisors) and attorneys understand the science involved when utilizing human remains detector (HRD) canines as a locating tool. The book covers the basic anatomy and physiology of canine olfaction and the unique characteristics of their scenting ability that allows dogs to be trained to locate distinct odors. Using concise and clear explanations and photographs the book reviews the science of forensic taphonomy. Factors that may affect the decomposition process are highlighted along with what the potential outcomes that may be encountered. The book examines how the odor of human remains is generated through various stages of decomposition and the manner in which environmental conditions in both land and water settings may affect that odor. Different types of background information that may help in determining possible search locations for missing individuals are included as well as assist the HRD canine handler in developing search plans are covered. Different tools and technologies that may be used in addition to an HRD canine team are included to help readers understand that are many ways to address searching for a decedent. Several case reports involving decedents found in both land and water settings in addition to different weather conditions are included to help the reader understand how the environment may have affected the condition of the decedent. This edition includes more case reports explaining how environmental factors were considered in HRD canine deployments in both land and water settings. Understanding which variables—and how such variables—can affect the state and condition of human remains as well as dispersion of odor from human remains will help canine handlers utilize their HRD canine more effectively as a locating tool. Death Decomposition and Detector Dogs Second Edition will help HRD canine handlers and other law enforcement personnel be better prepared to meet the challenges of their jobs before during and after searches for the missing. | Death Decomposition and Detector Dogs From Science to Scene

GBP 42.99
1

Physical Therapy and Massage for the Dog

Scentwork for Horses

Scentwork for Horses

Scentwork for Horses is the first practical guide on how to implement scentwork into the lives of domesticated horses enhancing behaviour welfare and the human-animal bond. Scentwork is a new discipline in the field for horse and handler and expert author Rachaël Draaisma arms the reader with a palette of information to enable them to put this technique into action. As well as theoretical background information on the nose of the horse and biomechanics Draaisma discusses how scentwork improves horses’ learning abilities development socialisation and their bond with the handler. Readers will learn how to have their horses explore their environment participate in scentwork games and follow a footstep track to find a missing person or food bag. Easily accessible for anybody working with horses at any level scentwork can be done in small areas as well as in larger spaces on various surfaces. Whether veterinarian behaviourist trainer animal-assisted therapist equine physiotherapist osteopath or interested horse owner this book promises to bring both you and the horse enormous benefits strengthening the human-animal bond. Rachaël Draaisma has always lived with and had a passion for dogs and horses. In 2002 she decided to make it her profession. Achieving several diplomas she started to work full time as a trainer and behavioural consultant first with dogs later with horses. Her best-selling book Language Signs and Calming Signals of Horses published by CRC Press in 2017 has been translated into several languages. Another pillar of Draaisma’s working life with horses revolves around equine mental stimulation and scentwork and she has developed an extensive method to undertake scent tracking with horses a new tool in enriching the human-equine relationship. Draaisma travels throughout Europe and the globe to provide workshops and lectures on calming signals of horses equine mental stimulation and scentwork. You can purchase scent bags to aid your scentwork practice at the author's personal website: www. scentworkforhorses. com or www. calmingsignalsofhorses. com

GBP 31.99
1

Demystifying Dog Behaviour for the Veterinarian

Pesticide Regulation Handbook A Guide for Users

No-Frills Physics A Concise Study Guide for Algebra-Based Physics

Practical Cardiology for Veterinary Nurses

Practical Cardiology for Veterinary Nurses

This concise textbook provides a comprehensive practical guide for veterinary nurses and technicians who wish to develop their knowledge confidence and skills when nursing the cardiac patient. Presentation of dogs or cats with heart disease is common and it is vital that nurses understand how to look after these patients appropriately and support owners through what can often be challenging times. The book: Begins with basic anatomy and physiology foundations required to understand the disease processes explained in later chapters Covers diseases seen in small animal practice including congenital disease heart failure and treatment options Gives the nurse a sound understanding of electrocardiography thoracic radiography and cardiac ultrasound: how to perform these and what they are seeing Covers the hands-on requirements of the veterinary nurse such as heart auscultation and feeling patient pulses Lists cardiac drugs explaining when and why pharmacology would be used as well as side effects Has a dedicated chapter on first aid Discusses chronic nursing management of heart conditions including remote monitoring support and care planning. The book is packed with learning features including a Glossary diagrams illustrations and tables in full colour concise end of chapter Key Points and Further Reading lists. Essential reading for student nurses and technicians as well as those in practice who need a quick reference 'on the ground' this is the book that general practice veterinary nurses have been waiting for. | Practical Cardiology for Veterinary Nurses

GBP 34.99
1

Health and Welfare of Brachycephalic (Flat-faced) Companion Animals A Complete Guide for Veterinary and Animal Professionals

Health and Welfare of Brachycephalic (Flat-faced) Companion Animals A Complete Guide for Veterinary and Animal Professionals

Health and welfare issues of brachycephalic (flat-faced) animals are one of the most pressing problems facing companion animals right now. Dogs in particular are suffering from a ‘brachycephalic crisis’ resulting from a perfect storm where predispositions to an array of health issues are amplified by a population boom for certain brachycephalic breeds such as the French Bulldog and Pug. But yet for many owners these dogs represent the perfect companion: endearing personas and cute looks in a socially desirable package. So where is the truth in all of this? This book will equip veterinary professionals animal welfare scientists breeders and owners with the fuller story about brachycephalic health and welfare. The first half of the book provides the context of how and why we are in this crisis offering in-depth historical social ethical communication nursing welfare epidemiological genetics and international perspectives. The second half shifts towards the clinical arena with chapters that cover the background diagnosis treatment and prevention of the many unique healthcare needs of brachycephalic animals. Cutting-edge knowledge is shared on a range of disciplines including respiratory disease ophthalmology dermatology dentistry neurology obesity reproduction and anesthesia. With twenty chapters written by world-leading experts lifetimes of experience and knowledge are condensed into the first book dedicated exclusively to brachycephaly in companion animals. This essential reference resource will inform challenge and stimulate; it will open your mind to new opportunities for you to improve the welfare of brachycephalic animals by your personal and collective choices and actions. But prepare to be surprised: you may just find that your views on brachycephaly in companion animals will be changed forever. | Health and Welfare of Brachycephalic (Flat-faced) Companion Animals A Complete Guide for Veterinary and Animal Professionals

GBP 39.99
1

RCSI Handbook of Clinical Surgery for Finals

RCSI Handbook of Clinical Surgery for Finals

Developed over previous editions by the Royal College of Surgeons in Ireland to support students attending the three RCSI universities this convenient handbook provides pragmatic guidance to the principles and practice of surgery that students can expect to encounter during undergraduate studies. Spanning the full range of surgical specialties information is presented in a convenient and clinically relevant format that takes the students through the patient journey from presenting symptoms and aetiology to investigations management and follow-up. The text written as easy-to-read and easy-to-remember bullet lists is supplemented throughout by tables management algorithms and colour illustrations. Key Features: • Concise – specifically for the undergraduate medical student by a highly experienced team of surgical educators • Accessible – bullet text ideal for rapid reference • Flexible – for use when on the ward and during finals revision • Complete - print book supplemented by video clips online question and answer material and an image library for the full learning and revision package Thoroughly updated this fifth edition has enhanced pedagogy and for the first time is accompanied by video clips and questions for self-testing. Covering the core surgical knowledge needed to become a safe and competent doctor the book will be an invaluable companion for clinical placements and during the critical run-up to final examinations. | RCSI Handbook of Clinical Surgery for Finals

GBP 36.99
1

How to Build a Puppy Into a Healthy Adult Dog

How to Build a Puppy Into a Healthy Adult Dog

Dogs do not demonstrate discomfort or pain in a way that can be easily translated by us humans so we often miss that they are physically struggling. Understanding that making some very simple changes to our homes activities exercise regimes and how we train our puppies will have a massive positive impact on our dogs' lives. Using her world-renowned Galen Myotherapy knowledge and approach Robertson suggests and explains in detail how small profoundly important but easy to implement changes can improve the way we not only look after and develop our puppies but also how maintenance of this easy programme continues your puppy’s journey through into healthy adolescence and maturity. Environment exercise and activity habits have deep ongoing effects and How to Build a Puppy . into a healthy adult dog explores ways in which positive change can be integrated easily into our normal lives. The book culminates into a full programme called the Galen Myotherapy Puppy Physical Development Programme©. Including: A dedicated section on anatomy explaining in a functional way how everything in the body interrelates to form a functional moving structure Practical advice that is made logical and easy to interpret by the use of clear comparative descriptions as well as clear diagrams and pictures showing the movement and biomechanics of dogs Exercises and activities in a practical programme for all situations that can be followed to help build good foundations A full pictorial explanation of why so many 'traditional' exercise routines and activities are in fact incredibly damaging for our dogs This book will help canine professionals better advise their clients but also empower all readers to make their own changes as well as having a better all-round understanding to enable more pertinent questions from their vet breeder or puppy trainer. | How to Build a Puppy Into a Healthy Adult Dog

GBP 21.99
1

The Easy Guide to Focused History Taking for OSCEs

Foundational and Applied Statistics for Biologists Using R

Foundational and Applied Statistics for Biologists Using R

Full of biological applications exercises and interactive graphical examples Foundational and Applied Statistics for Biologists Using R presents comprehensive coverage of both modern analytical methods and statistical foundations. The author harnesses the inherent properties of the R environment to enable students to examine the code of complicated procedures step by step and thus better understand the process of obtaining analysis results. The graphical capabilities of R are used to provide interactive demonstrations of simple to complex statistical concepts. Assuming only familiarity with algebra and general calculus the text offers a flexible structure for both introductory and graduate-level biostatistics courses. The first seven chapters address fundamental topics in statistics such as the philosophy of science probability estimation hypothesis testing sampling and experimental design. The remaining four chapters focus on applications involving correlation regression ANOVA and tabular analyses. Unlike classic biometric texts this book provides students with an understanding of the underlying statistics involved in the analysis of biological applications. In particular it shows how a solid statistical foundation leads to the correct application of procedures a clear understanding of analyses and valid inferences concerning biological phenomena. Web ResourceAn R package (asbio) developed by the author is available from CRAN. Accessible to those without prior command-line interface experience this companion library contains hundreds of functions for statistical pedagogy and biological research. The author’s website also includes an overview of R for novices.

GBP 42.99
1

Pediatric Emergency Medicine Illustrated Clinical Cases Second Edition

AI for Arts

AI for Sports

AI for School Teachers

AI for Physics

AI for Diversity

Electronics for Scientists

Electronics for Scientists

Electronics for Scientists provides a practical and concise introduction to electrical circuits signals and instrumentation for undergraduate students in the physical sciences. No previous familiarity with electronics is required and concepts are grounded in the relevant physics. The book aims to give students the electronics background needed to be successful in experimental science. The book begins with the fundamentals of DC circuits. This is followed by AC circuits and their analysis using the concept of impedance. The transfer function is introduced and used to analyze different types of filter circuits. The conversion between time-domain and frequency-domain signal representations is reviewed. Transmission lines are introduced and used to motivate the different approach to designing microwave-frequency circuits as compared to lower-frequency circuits. The physics of semiconductors is reviewed and used to understand the behavior of diodes and transistors and a number of diode and transistor circuits are analyzed. The operational amplifier (op-amp) is introduced and several op-amp circuits are analyzed. Techniques for quantifying noise in electrical measurements are described and common sources of noise are discussed. The last major topic is digital circuits which include analog-to-digital conversion logic gates and digital memory circuits. The book concludes with a brief introduction to quantum computing. Designed for a one-semester course this book brings together a range of topics relevant to experimental science that are not commonly found in a single text. Worked examples are provided throughout the book and each chapter concludes with a set of problems to reinforce the material covered. The subject of electronics is indispensable to a wide array of scientific and technical fields and this book seeks to provide an approachable point of access to this rich and important subject.

GBP 32.99
1

Get Through MRCOG Part 3 Clinical Assessment Second Edition

Collaborative Worldbuilding for Video Games