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Introduction to Forensic DNA Evidence for Criminal Justice Professionals

Introduction to Forensic DNA Evidence for Criminal Justice Professionals

The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting yet for those with limited scientific knowledge understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed for nonscientific readers who need to learn how to effectively use forensic DNA in criminal cases. Written by a forensic scientist world renowned for her expertise in clothing examination the book provides a balanced perspective on the weight of DNA evidence. Going beyond a simple explanation of the methodology it arms attorneys and other criminal justice professionals with knowledge of the strengths and limitations of the evidence including the danger in relying on DNA statistical probabilities in the determination of guilt. The book covers the most common DNA methods used in criminal trials today nuclear DNA short tandem repeat (STR) techniques mitochondrial DNA and Y-STR profiling. It helps prosecutors know when to emphasize DNA evidence or proceed with trial in the absence of such evidence. It assists defense lawyers in knowing when to challenge DNA evidence and perhaps employ an independent expert when to focus elsewhere or when to secure the advantage of an early guilty plea. By imparting practical and theoretical knowledge in an accessible manner the book demystifies the topic to help both sides of the adversarial system understand where DNA evidence fits within the context of the case.

GBP 180.00
1

Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

A powerful tool in the identification of individuals DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories Forensic Analysis of Biological Evidence: A Laboratory Guide for Serological and DNA Typing introduces readers to the science of serological analysis and DNA typing methods and provides a thorough background of the molecular techniques used to determine an individual‘s identity or parental lineage. Originally published as Forensic DNA Analysis: A Laboratory Manual this revised work offers updated exercises and protocols for all kinds of DNA and serological analyses with delineated objectives step-by-step procedures and required laboratory supplies. Each exercise in this manual: Provides an overview of forensic DNA analysis Explains the sources or types of biological material used in a particular DNA analysis Supplies the background principles and practical methodology for specific serological analysis and DNA typing techniques Simulates human forensic testing and can also be used to simulate a wide range of applications for genetic analysis The book contains an extensive glossary to make readers familiar with terminology used in the forensic analysis of biological evidence as well as basic terms used in molecular biology. Those who master the material in this volume will understand the methodology of the investigation in DNA typing develop an understanding of the scientific principles involved in serology and DNA analysis and succeed in analyzing and interpreting the data generated in each exercise with clarity and confidence. | Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

GBP 180.00
1

DNA Nanoscience From Prebiotic Origins to Emerging Nanotechnology

Diagnostic MRI in Dogs and Cats

Diagnostic MRI in Dogs and Cats

Diagnostic MRI in Dogs and Cats makes the vast and increasingly complex topic of clinical MRI in small animals accessible to all veterinarians. With the increasing availability of MRI technology there is also a pressing need for expertise in interpreting these images. This is the first reference textbook to provide a well-illustrated and comprehensive overview of the current knowledge focusing on imaging appearance rather than on clinical signs or treatment. With chapters on MRI physics and technology as well as sections on specific anatomical regions the book functions as a stand-alone reference for the reader whether they be a radiology/neurology resident in training or a practitioner with a need to learn about veterinary clinical MRI. Includes both evidenced-based material and the authors' personal experience providing an excellent overview of current knowledge in the field. Contributors are international leaders in the field. Bullet points format and table summaries throughout the book keep the concepts concise and organized. Richly illustrated with over 650 annotated images showcasing the main features of the disease processes. Images are obtained at all magnet field strengths so as to reflect the current reality of veterinary MRI which uses low- mid- and high-field magnets. The chapters on physics and MRI technology are concise and accessible using many visual aids and diagrams and avoiding abstract concepts and equations whenever possible. Within each anatomical section each chapter focuses on a disease category of that body region. When it is important to understand the imaging appearance the pathophysiology is reviewed and imaging features of prognostic relevance are detailed. This practical yet thoroughly comprehensive book is primarily an evidence-based learning resource for trainees but will also aid practising veterinarians who have less MRI experience.

GBP 240.00
1

Problem Solving for Engineers

Problem Solving for Engineers

Whatever their discipline engineers are routinely called upon to develop solutions to all kinds of problems. To do so effectively they need a systematic and disciplined approach that considers a range of alternatives taking into account all relevant factors before selecting the best solution. In Problem Solving for Engineers David Carmichael demonstrates just such an approach involving problem definition generation of alternative solutions and ultimately the analysis and selection of a preferred solution. David Carmichael introduces the fundamental concepts needed to think systematically and undertake methodical problem solving. He argues that the most rational way to develop a framework for problem solving is by using a systems studies viewpoint. He then outlines systems methodology modeling and the various configurations for analysis synthesis and investigation. Building on this the book details a systematic process for problem solving and demonstrates how problem solving and decision making lie within a systems synthesis configuration. Carefully designed as a self-learning resource the book contains exercises throughout that reinforce the material and encourage readers to think and apply the concepts. It covers decision making in the presence of uncertainty and multiple criteria including that involving sustainability with its blend of economic social and environmental considerations. It also characterizes and tackles the specific problem solving of management planning and design. The book provides for the first time a rational framework for problem solving with an engineering orientation.

GBP 180.00
1

Organelle and Molecular Targeting

Organelle and Molecular Targeting

We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines such as the mRNA vaccines encoding the viral spike protein demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA DNA and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines reducing the required dose and therefore the biomanufacturing demand. Likewise improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies cancer neurodegeneration progerias diabetes and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status demand and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students scientists and clinicians contributing to modern medicine.

GBP 200.00
1

Introduction to High Performance Computing for Scientists and Engineers

Introduction to High Performance Computing for Scientists and Engineers

Written by high performance computing (HPC) experts Introduction to High Performance Computing for Scientists and Engineers provides a solid introduction to current mainstream computer architecture dominant parallel programming models and useful optimization strategies for scientific HPC. From working in a scientific computing center the authors gained a unique perspective on the requirements and attitudes of users as well as manufacturers of parallel computers. The text first introduces the architecture of modern cache-based microprocessors and discusses their inherent performance limitations before describing general optimization strategies for serial code on cache-based architectures. It next covers shared- and distributed-memory parallel computer architectures and the most relevant network topologies. After discussing parallel computing on a theoretical level the authors show how to avoid or ameliorate typical performance problems connected with OpenMP. They then present cache-coherent non-uniform memory access (ccNUMA) optimization techniques examine distributed-memory parallel programming with message passing interface (MPI) and explain how to write efficient MPI code. The final chapter focuses on hybrid programming with MPI and OpenMP. Users of high performance computers often have no idea what factors limit time to solution and whether it makes sense to think about optimization at all. This book facilitates an intuitive understanding of performance limitations without relying on heavy computer science knowledge. It also prepares readers for studying more advanced literature. Read about the authors' recent honor: Informatics Europe Curriculum Best Practices Award for Parallelism and Concurrency.

GBP 180.00
1

Optimization for Energy Systems and Supply Chains Fundamentals and Applications

Optimization for Energy Systems and Supply Chains Fundamentals and Applications

To curb the impacts of rising CO2 emissions the Intergovernmental Panel on Climate Change report states that a net zero target needs to be achieved by the year 2055. Experts argue that this is a critical time to make important and accurate decisions. Thus it is essential to have the right tools to efficiently plan and deploy future energy systems and supply chains. Mathematical models can provide decision-makers with the tools required to make well-informed decisions relating to development of energy systems and supply chains. This book provides an understanding of the various available energy systems the basics behind mathematical models the steps required to develop mathematical models and examples/case studies where such models are applied. Divided into two parts one covering basics for beginners and the other featuring contributed chapters offering illustrative examples this book: Shows how mathematical models are applied to solve problems in energy systems and supply chains Provides fundamentals of the working principles of various energy systems and their technologies Offers basics of how to formulate and best practices for developing mathematical models topics not covered in other titles Features a wide range of case studies Teaches readers to develop their own mathematical models to make decisions on energy systems This book is aimed at chemical process mechanical and energy engineers. | Optimization for Energy Systems and Supply Chains Fundamentals and Applications

GBP 180.00
1

Engineered Concrete Mix Design and Test Methods Second Edition

Engineered Concrete Mix Design and Test Methods Second Edition

As every civil engineer knows Portland Cement is the most versatile and important material of construction and will probably remain so far into the future. Yet few books if any exist that offer an in-depth analysis of the mixing and testing methods of this vital hydraulic cement. This statement written about the first edition of Engineered Concrete: Mix Design and Test Methods remains as true today as it was ten years ago. Revised and updated the second edition of this groundbreaking resource completely covers Portland Cement Portland Cement Concrete and their uses. See what‘s new in the Second Edition: New coverage of the latest concrete technologies such as high-performance and lightweight concrete Several new tests and sample tearsheets Additional and updated data sheets The body of the book is divided into several sections with the first explaining how concrete batches are designed mixed and measured for various consistencies. Another section details the tests of the primary component materials of concrete other than water namely Portland Cement aggregates and mortar while the final section includes some of the fundamental concrete testing procedures for different strength parameters in conformity with the standards of the American Society for Testing Materials. Solidly researched and written the book supplies a fundamental understanding of cement concrete and mixing and testing methods that allow readers to produce the most economical combinations of concrete materials and satisfy performance requirements and specifications. | Engineered Concrete Mix Design and Test Methods Second Edition

GBP 180.00
1

Microbiome-Host Interactions

Microbiome-Host Interactions

Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans animals plants and the environment. In humans microbiota are associated with the gut skin and genital oral and respiratory organs. The plant microbial community is referred to as holobiont and it is influential in the maintenance and health of plants which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant animal human and environmental microbiome interactions. The book covers microbiota in polar soil environments in health and disease in Caenorhabditis elegans and in agroecosystems as well as in rice root and actinorhizal root nodules speleothems and marine shallow-water hydrothermal vents. Moreover this book provides comprehensive accounts of advanced next-generation DNA sequencing metagenomic techniques high-throughput 16S rRNA sequencing and understanding nucleic acid sequence data from fungal algal viral bacterial cyanobacterial actinobacterial and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats including Antarctic hydrothermal vents speleothems oral skin gut feces reproductive tract soil root root nodules forests and mangroves Illustrates the high-throughput amplicon sequencing computational techniques involved in the microbiota analysis downstream analysis and visualization and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota skin microbiome impact in dermatologic disease prevention and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students teachers researchers microbiologists computational biologists and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences

GBP 180.00
1

Optics for Engineers

Optics for Engineers

The field of optics has become central to major developments in medical imaging remote sensing communication micro- and nanofabrication and consumer technology among other areas. Applications of optics are now found in products such as laser printers bar-code scanners and even mobile phones. There is a growing need for engineers to understand the principles of optics in order to develop new instruments and improve existing optical instrumentation. Based on a graduate course taught at Northeastern University Optics for Engineers provides a rigorous practical introduction to the field of optics. Drawing on his experience in industry the author presents the fundamentals of optics related to the problems encountered by engineers and researchers in designing and analyzing optical systems. Beginning with a history of optics the book introduces Maxwell‘s equations the wave equation and the eikonal equation which form the mathematical basis of the field of optics. It then leads readers through a discussion of geometric optics that is essential to most optics projects. The book also lays out the fundamentals of physical optics polarization interference and diffraction in sufficient depth to enable readers to solve many realistic problems. It continues the discussion of diffraction with some closed-form expressions for the important case of Gaussian beams. A chapter on coherence guides readers in understanding the applicability of the results in previous chapters and sets the stage for an exploration of Fourier optics. Addressing the importance of the measurement and quantification of light in determining the performance limits of optical systems the book then covers radiometry photometry and optical detection. It also introduces nonlinear optics. This comprehensive reference includes downloadable MATLAB code as well as numerous problems examples and illustrations. An introductory text for

GBP 180.00
1

Handbook for Death Scene Investigators

Introduction to Market Access for Pharmaceuticals

Advanced Technologies for Meat Processing

Advanced Technologies for Meat Processing

As with the first edition the main goal of Advanced Technologies for Meat Processing is to provide the reader with recent developments in new advanced technologies for the full meat- processing chain. This book is written by distinguished international contributors with recognized expertise and excellent reputations and brings together all the advances in a wide and varied number of technologies that are applied in different stages of meat processing. This second edition contains 21 chapters combining updated and revised versions of several chapters with entirely new chapters that deal with new online monitoring techniques like hyperspectral imaging and Raman spectroscopy the use of nanotechnology for sensor devices or new packaging materials and the application of omics technologies like nutrigenomics and proteomics for meat quality and nutrition. The book starts with the control and traceability of genetically modified farm animals followed by four chapters reporting the use of online non-destructive monitoring techniques like hyperspectral imaging and Raman spectroscopy real-time PCR for pathogens detection and nanotechnology-based sensors. Then five chapters describe different advanced technologies for meat decontamination such as irradiation hydrostatic and hydrodynamic pressure processing other non-thermal technologies and the reduction in contaminants generation. Nutrigenomics in animal nutrition and production is the object of a chapter that is followed by five chapters dealing with nutritional-related issues like bioactive peptides functional meats fat and salt reduction processing of nitrite-free products and the use of proteomics for the improved processing of dry-cured meats. The last four chapters are reporting the latest developments in bacteriocins against meat-borne pathogens the functionality of bacterial starters modified atmosphere packaging and the use of new nanotechnology-based materials for intelligent and edible packaging.

GBP 180.00
1

Maternal-Fetal and Obstetric Evidence Based Guidelines Two Volume Set Fourth Edition

Instrumentation for Trace Organic Monitoring

Hydrophilic Polymer Coatings for Medical Devices

A Course in Mathematical Methods for Physicists

Supply Chain Management for Engineers

Supply Chain Management for Engineers

Originally taught mainly in business schools supply chain management has become a common elective and graduate course in engineering colleges. The increasing demand for engineers with supply chain knowledge has fed this shift. However supply chain management textbooks that have a reasonable coverage of quantitative analysis techniques are few and far between. Concise straightforward and easy-to-read Supply Chain Management for Engineers uses practical problems to introduce key concepts and cultivate students problem-solving skills. Helping students hone their analytical skills and develop the ability to solve real-world problems the book: Includes a simulation game for practicing supply chain management skills Covers the use of practical software tools including Gurobi Optimizer and Microsoft EXCEL Facilitates the use of problem-based learning (PBL) pedagogy Provides a theoretical framework for supply chain design and supplier selection Focusing on quantitative aspects this book uses example problems to introduce key concepts and case studies to strengthen students analysis and synthesis skills. In addition to exercises this book also provides several problems that are relatively complicated and can be used as mini projects that link theoretical concepts to practical problem solving. It also presents a simulation game where students can play the roles of suppliers OEMs and retailers within a supply chain environment to practice the skills they acquire. It also stresses the importance of integrating engineering optimization techniques with business strategic thinking. These features and more give students the supply chain knowledge and problem-solving skills increasingly required for engineers entering the work force.

GBP 180.00
1

A Geology for Engineers

Numerical Methods for Differential Equations A Computational Approach

Bacterial Starter Cultures for Food

Inductive Learning Algorithms for Complex Systems Modeling

Hydroponics for the Home Grower

Hydroponics for the Home Grower

Hydroponics offers many advantages to traditional soil-based horticulture. These include greater control over many of the limiting factors such as light temperature and pests as well as the ability to grow plants in all seasons. With instruction from one of the top recognized authorities worldwide Hydroponics for the Home Grower gives you step-by-step guidance on how to grow tomatoes peppers cucumbers eggplant lettuce arugula bok choy and various herbs year-round within your home or in a backyard greenhouse. Read an Interview with Dr. Resh here With Dr. Howard Resh‘s help you‘ll learn: Background information on how hydroponics evolved The nutritional and environmental demands of plants and how to control these factors How to provide formulations of nutrients optimal to the plants you wish to grow The many different hydroponic systems you can purchase or build for yourself Designs for different types of greenhouses with components to fit your personal taste and budget Crop selection and step-by-step procedures including seeding transplanting training pest and disease control and harvesting along with when to plant and when to change crops How you can grow microgreens on your kitchen counter The book includes an appendix with sources of seeds and other supplies along with helpful websites and lists of books articles and conferences on growing hydroponically and caring for your crops. By following the guidelines in this book you‘ll understand everything you need to know to get your home-growing operation up and running in no time.

GBP 180.00
1