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Forensic DNA Transfer

Forensic DNA Transfer

Forensic DNA Transfer provides a guide to the recognition and current understanding of DNA transfer in forensic criminal investigations. Increased improvements in technology mean that it is now routinely possible to obtain DNA profiles from non-visible deposits. How or when the DNA in question was deposited may be an issue in the context of the case especially if the donor of the DNA is not in dispute. A DNA profile alone cannot reveal when or how that DNA was deposited at a crime scene nor can it reveal the body matter from which it originated. Issues of transfer associated with activities may be debated—which the traditional discrimination purpose of DNA profiling cannot address. DNA may be everywhere and anywhere—in homes at workplaces during transport and on personal items including clothing. DNA from a person may be on an object they have never contacted or in a room they have never entered. Concepts discussed in the book include non-self DNA on hands through day-to-day activities the prevalence of background DNA in the environment and perhaps on the exhibit the persistence of any DNA transferred and that a DNA result will depend on these variables as well as recovery techniques. Since DNA may be transferred to an exhibit: (a) during the commission of a crime (b) before the crime and/or (c) after the crime through handling examination and testing this book covers various transfer pathways and sources of DNA. Documented cases of inadvertent transfer of DNA resulting in wrongful convictions or the misdirection of criminal investigations are discussed—with an emphasis on contamination mitigation throughout the entire process. Forensic DNA Transfer examines the additional complexity resulting from non-visible deposits of DNA that impact on sampling and testing regimes. The changing understanding of the composition of purported 'touch DNA' deposits from the skin including extracellular DNA transported via body secretions is described. Further the newer focus on interpreting DNA evidence—using activity level propositions and the rationale and associated issues—is also discussed.

GBP 46.99
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Forensic DNA Analysis Current Practices and Emerging Technologies

Forensic DNA Analysis Current Practices and Emerging Technologies

The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing forensic casework family lineage studies identification of human remains and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize document collect and store it. The remaining chapters examine:The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remainsStudies carried out on the use of both messenger RNA and small (micro) RNA profilingReal-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotypingCapillary electrophoresis (CE) as a tool for forensic DNA analysisNext-generation short tandem repeat (STR) genotyping kits for forensic applications the biological nature of STR loci and Y-chromosome STRs (Y-STRs)Mitochondrial DNA (mtDNA) sequence analysisSingle nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in typing highly degraded DNADeep-sequencing technologiesThe current state of integrated systems in forensic DNA analysis The book concludes by discussing various aspects of sample-processing training and the entities that provide such training programs. This volume is an essential resource for students researchers teaching faculties and other professionals interested in human identification/forensic DNA analysis. | Forensic DNA Analysis Current Practices and Emerging Technologies

GBP 77.99
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Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications: An Interdisciplinary Perspective Second Edition is fully updated to outline the latest advances in forensic DNA testing techniques and applications. It continues to fill the need for a reference book for people working in the field of forensic molecular biology testing and research as well as individuals investigating and adjudicating cases involving DNA evidence whether they be civil or criminal cases. DNA techniques have greatly impacted obvious traditional forensic areas but such advances have also positively affected myriad new areas of research and inquiry. It is possible today to think about solving forensic problems that were simply unheard of even a few years ago. As such the book pulls all relevant research and applied science together into a detailed and comprehensive collection. Part I begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples mitochondrial DNA testing Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs) and X SNP and STR testing. It also explores low copy number DNA typing mixtures and quality assurance and control. Part II moves on to cover the various uses and applications of analyzing collected physical evidence victim identification in mass disasters analyzing animal DNA forensic botany and other unique applications. Part III is dedicated to the latest advances and developments in human molecular biology and Part IV looks at policies and laws and ethics governing DNA evidence and its utilization in various cases and the courts. Forensic DNA Applications Second Edition covers cutting-edge research and advancements in the field and is the most up-to-date reference available. Edited and contributed to by the world's foremost leaders in the field it is a must-have reference for established professionals and an essential resource to legal professionals—lawyers and judges dealing with civil and criminal cases involving DNA technology—as well as students entering the fields of genetics and forensic DNA analysis. | Forensic DNA Applications An Interdisciplinary Perspective

GBP 56.99
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Artificial DNA Methods and Applications

Artificial DNA Methods and Applications

Combining elements of biochemistry molecular biology and immunology artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis hybridization amplification protein engineering anti-sense technology DNA vaccines protein vaccines recombinant antibodies screening for genetic and pathogenic diseases development of materials with new biochemical and structural properties and many more. Artificial DNA: Methods and Applications introduces the concept of artificial DNA that has been rationally designed and explains how it may be exploited in order to develop products that will achieve your intended purpose. The first part of the book covers methods of oligonucleotide synthesis and direct applications of synthetic DNA. The second part describes methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. The authors also discuss the different trends and future developments within each application area . With state-of-the art research the contributing authors describe how to engineer proteins using rational and semi-rational design to exhibit the desired traits and detail the various amplification reactions and hybridization techniques for modeling evolution and for use in basic research. The only text devoted to this subject Artificial DNA offers a comprehensive review that allows you to understand the strategy design and applications of synthetic oligonucleotides. | Artificial DNA Methods and Applications

GBP 59.99
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Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures how to assign a likelihood ratio and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods the polymerase chain reaction (PCR) capillary electrophoresis (CE) likelihood ratios (LRs) and their interpretation and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES:• The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods heretofore unpublished previously provide a means to innovate deconvoluting a mixed DNA profile assign an LR and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i. e. “It’s not me it was my brother”) and discusses strategies for the validation of probabilistic genotyping softwareForensic DNA Profiling fills the void for labs unfamiliar with LRs and moving to probabilistic solutions and for labs already familiar with LRs but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians students and legal professionals seeking to understand and apply the techniques covered. | Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

GBP 44.99
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Environmental Impact Assessment A Guide to Best Professional Practices

Environmental Impact Assessment A Guide to Best Professional Practices

Under the best of circumstances preparing an environmental impact assessment (EIA) can be a complex and challenging task. Experience indicates that the scope and quality of such analyses varies widely throughout the U. S. as well as internationally. Written to help practitioners and decision-makers apply best professional practices in the development of EIAs Environmental Impact Assessment: A Guide to Best Professional Practices provides an in depth yet practical direction for developing a defensible analysis that meets best professional practices. The book describes preparation of five distinct types of assessments: Cumulative Impact Assessment (CIA) Preparing Greenhouse Emission Assessments Preparing Risk Assessments and Accident Analyses Social Impact Assessment (SIA) and Environmental Justice The International Environmental Impact Assessment Process Guiding Principles To date there is significant variation and disagreement about how such analyses should be prepared. The author introduces best professional practices (BPP) for preparing such EIAs that is intended to meet decision-making and regulatory expectations. He supplies a comprehensive and balanced skill set of tools techniques concepts principles and practices for preparing these assessments. He also includes directions for developing a comprehensive Environmental Management Systems which can be used to monitor and implement final decisions for such analyses. While the book references the U. S. National Environmental Policy Act (NEPA) most of this guidance is generally applicable to any international EIA process consistent with NEPA. With thorough coverage of all aspects of assessments the book presents a theoretical introduction to the subject as well as practical guidance. It delivers state-of-the-art tools techniques and approaches for resolving EIA problems. | Environmental Impact Assessment A Guide to Best Professional Practices

GBP 74.99
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Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

Dogs detect scent from a source that is carried to them in a plume by the wind. The most important tool for a detector dog handler to have on searches is a knowledge of scent plume movement or scent dynamics (the science of scent movement). Such knowledge resides primarily in scientific journals that are largely inaccessible to detector dog handlers and written in language that is difficult to understand. Detector Dogs and the Science of Scent Movement: A Handler’s Guide to Environments and Procedures retrieves reviews and interprets the results of pertinent scientific research on scent dynamics and presents these results in terms that are easier for handlers to understand. Information on the physiology of the dog’s nose their sense of smell and the properties of scent provide the essential information on the process of scenting. The composition of training aids for explosives narcotics human remains and other sources is discussed. Recommendations are made on the use of training aids their placement during training and the resulting availability of scent. Potential problems and handler errors in the use of training aids are also examined. The characteristics of scent plumes and how wind influences their movement are a key focus of the book. The primary task for the handler is to get the dog into the scent plume so that the dog can detect the scent and follow it to the source the handler seeks. As such a knowledge of scent and scent plume movement will vastly improve the ability of the handler to accomplish this task. The influence of weather and physical settings such as terrain vegetation ground cover soil and water on scent movement are examined in detail. Strategies for searching detecting and locating sources in all physical settings are presented. Specific effects associated with hills and mountains fields and forests bare soils and soils covered by vegetation different soil types and lakes and rivers are examined in detail. This includes specific recommendations are made about weather and physical settings that result in higher probability of success on searches. Detector Dogs and the Science of Scent Movement will be a vital resource for K9 handles in the private and public sectors—including in Homeland Security law enforcement and military settings—as well as a useful guide for lawyers forensic and investigative professionals who need to better understand K9 operations. | Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

GBP 44.99
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Preparing NEPA Environmental Assessments A User’s Guide to Best Professional Practices

Preparing NEPA Environmental Assessments A User’s Guide to Best Professional Practices

Although upwards of 50 000 environmental assessments (EAs) are prepared annually—compared to some 500 environmental impact statements (EISs)—the focus of U. S. National Environmental Policy Act (NEPA) regulations is on defining requirements for preparing EISs. Written by Charles Eccleston and J. Peyton Doub who have established themselves among the top environmental experts in the world Preparing NEPA Environmental Assessments: A User’s Guide to Best Professional Practices fills the need for an authoritative and comprehensive guide on how to prepare EAs. Bridging the regulatory gap this book identifies relevant EIS regulatory requirements that can be logically interpreted to also apply to EAs. It compiles and synthesizes information scattered throughout NEPA’s regulations executive orders and guidance documents and incorporates case law to provide additional clarification. The authors also draw on the professional experiences and best professional practices (BPP) of NEPA practitioners. From the fundamentals to more advanced topics the book presents a consistent methodology to help beginners students and professionals manage analyze and write legally sufficient EAs. It addresses dilemmas that have traditionally plagued preparation of EAs provides BPPs tools and approaches for resolving problems and introduces methods for streamlining the EA process. Building on Eccleston’s previous guide to EAs Effective Environmental Assessments: How to Manage and Prepare NEPA Assessments (2001) this book reflects the rapid changes in government policy over the past ten years. An indispensable source of practical information it provides readers with step-by-step direction and best practices for preparing defensible EAs. | Preparing NEPA Environmental Assessments A User’s Guide to Best Professional Practices

GBP 56.99
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Cadaver Dog Handbook Forensic Training and Tactics for the Recovery of Human Remains

Management Options in Breast Cancer Case Histories Best Practice and Clinical Decision-Making

Handbook of Mitochondrial Dysfunction

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery

The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced and processes seamlessly integrated. This microscale advantage translates into greater sensitivity more accurate results and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology its limitations and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods microfluidic operations chemical separations sample preparation and injection methods detection technology and various chemical and biological analyses. Other topics of interest include the use of polymeric chips fluid flow valve and control single-cell analysis DNA and RNA amplification techniques DNA hybridization immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.

GBP 44.99
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Manual of Forensic Science An International Survey

Viva Practice for the FRCS(Urol) and Postgraduate Urology Examinations

Manipulation of the Avian Genome

Forensic Laboratory Management Applying Business Principles

Forensic Laboratory Management Applying Business Principles

New technologies including DNA and digital databases that can compare known and questioned exemplars have transformed forensic science and greatly impacted the investigative process. They have also made the work more complicated. Obtaining proper resources to provide quality and timely forensic services is frequently a challenge for forensic managers who are often promoted from casework duties and must now learn a whole new set of leadership skills. The interdisciplinary and scientific nature of laboratories requires strong leadership ability to manage complex issues often in adversarial settings. Forensic Laboratory Management: Applying Business Principles provides laboratory managers with business tools that apply the best science to the best evidence in a manner that increases the efficiency and effectiveness of their management decision making. The authors present a performance model with seven recommendations to implement illustrating how forensic managers can serve as leaders and strategically improve the operation and management in scientific laboratories. Topics include:Key business metrics and cost–benefit analysesEthical lapses: why they occur possible motives and how problems can be preventedForensic training education and institutesISO/IEC 17025 accreditation implementationThe book includes case studies simulating a working laboratory in which readers can apply business tools with actual data reinforcing discussion concepts. Each chapter also includes a brief review of current literature of the best management theories and practice. The downloadable resources supply two mock trial transcripts and associated case files along with PowerPoint® slides from Dr. George Carmody’s workshop on Forensic DNA Statistics and Dr. Doug Lucas’s presentation on ethics. | Forensic Laboratory Management Applying Business Principles

GBP 62.99
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Pressure and Temperature Well Testing

Pressure and Temperature Well Testing

The book comprises two parts: Pressure and Flow Well Testing (Part I) and Temperature Well Testing (Part II) and contains numerous authors’ developments. Due to the similarity in Darcy’s and Fourier’s laws the same differential diffusivity equation describes the transient flow of incompressible fluid in porous medium and heat conduction in solids. Therefore it is reasonable to assume that the techniques and data processing procedures of pressure well tests can be applied to temperature well tests. The book presents new methods to determine the formation of permeability and skin factors from tests conducted in simulated wells designing interference well tests processing constant bottom-hole pressure tests estimation of the formation temperature and geothermal gradients from temperature surveys and logs in-situ determination of the formation thermal conductivity and contact thermal resistance of boreholes temperature regime of boreholes (cementing of production liners) and the recovery of thermal equilibrium in deep and superdeep wells. Processing and analysis of pressure and geothermal data are shown on numerous field examples from different regions of the world. The book is intended for students engineers and researchers in the field of hydrocarbon geophysics and geology groundwater searching and exploitation and subsurface environment examination. It will be also useful for specialists studying pressure and temperature in parametric deep and superdeep wells. | Pressure and Temperature Well Testing

GBP 59.99
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Liquid Chromatography for the Analyst

Electronics Fundamentals for the Water and Wastewater Maintenance Operator

Organ Preservation for Transplantation

Organ Preservation for Transplantation

The first edition of this book Basic Concepts in Organ Procurement Perfusion and Preservation for Transplantation was published 27 years ago in 1982 when organ procurement and preservation began to advance in the study of the best ways to preserve organs for transplantation. The second edition Organ Procurement and Preservation for Transplantation 2nd Edition followed 15 years later in 1997 with the goal of finding common denominators in the best preservation techniques for transplantation. In this current third edition 11 years after the second edition similar goals are still pursued of defining the best preservation methods but there is now more evidence including results and new advances have reached publication and are being incorporated into ischemia and reperfusion techniques and organ preservation studies. Many preservation solutions have been introduced important preservation solution components have been better defined and improved perfusion methods are being considered especially for the increasing number of organ donors with non-beating hearts who are being sought for transplantation. This edition (2009) engaged experts in the field of organ preservation to review update and rewrite each of the chapters. Crafted in collaboration with Luis H. Toledo-Pereyra the text is eminently informative and easily understandable. Each solid organ that can be transplanted has an entire chapter devoted to the particular methods of its preservation. One chapter apiece in other words features insights on the preservation of the kidney the liver the pancreas the small bowel the heart and the heart-lung. The title of the present book has been shortened to better represent its content. Thus Organ Preservation for Transplantation 3rd Edition demonstrates a more accurate depiction of its current status. Nevertheless the goal of this book remains exactly the same as in the first edition that is “to analyze the most important aspects of organ procurement perfusion and preservation for transplantation”.

GBP 69.99
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Mechanical Wear Fundamentals and Testing Revised and Expanded

Scientific Protocols for Forensic Examination of Clothing

Scientific Protocols for Forensic Examination of Clothing

When a crime or other incident takes place clothing items are often present or left behind and can become directly involved in the case itself. Items of clothing are thus one of the most common types of exhibit examined in court. They can provide valuable information in cases of violent crimes such as homicide or rape as well as in burglary robbery arson and vehicular accidents. A unique reference in the forensic arenaThe first of its kind Scientific Protocols for Forensic Examination of Clothing discusses the forensic examination of clothing in criminal cases. It examines the ramifications of DNA profiling and its effect on the screening approach to clothing examination. Coverage includes protocols and procedures preliminary assessment examination testing and sampling quality assurance and control and the significance of results. Applicable to a myriad of readersSuitable for a wide range of readers this book is designed for examiners trying to decide how to approach a clothing examination those looking for more information on a specific topic laboratory quality assurance officers in need of a reliable reference as well as attorneys investigators archaeologists and curators. Expert authors Author Jane Moira Taupin has testified as a forensic expert more than 130 times. Chesterene Cwiklik is a founder of the Pacific Coast Forensic Science Institute. Their expertise makes this a valuable resource for all those who examine clothing items and interpret subsequent findings.

GBP 69.99
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Optimizing Small Multi-Rotor Unmanned Aircraft A Practical Design Guide

The Complete Guide to the ABC Molecular Biology Certification Exam

The Complete Guide to the ABC Molecular Biology Certification Exam

In 2009 the National Academy of Sciences (NAS) authored the report Strengthening Forensic Science in the United States: A Path Forward. In it the Committee expressed the need for accreditation and certification. Accreditation long recognized by public labs as an important benchmark in quality was recognized as an important way to standardize laboratories that provide forensic services. Certification can play an important role as a method of oversight in the forensic sciences—something also recommended by the - National Commission on Forensic Science in October 2014. The Complete Guide to the ABC's Molecular Biology is a professional certification examination preparation text for forensic scientists taking the American Board of Criminalistics Examination in Molecular Biology. The book serves as a resource for forensic scientists—who are facing more and more pressure to become certified—to support them in their pursuit of forensic certification. In the years since the NAS report was published there has been increased discussion of forensic certification requirements. ABC’s Molecular Biology exam is a quality certification and learning the concepts for it will invariably help any professional working in the field. The book prepares readers in all relevant topic areas including: accreditation safety biological screen principles anatomy and cell biology crime scene and evidence handling concepts in genetics biochemistry statistics DNA evidence and DNA testing. The book will be particularly helpful for forensic science laboratory technicians police and investigations professionals forensic serology and DNA analysts attorneys and forensic science students. This study guide follows the guidelines for the exam and presents all the information necessary to prepare individuals to pass the exam. | The Complete Guide to the ABC Molecular Biology Certification Exam

GBP 74.99
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