2.804 results (0,24060 seconds)

Show all filters

Brand

Merchant

Price (EUR)

Show all

Reset filter

Products
From
Shops

The Blood-Cerebrospinal Fluid Barrier

The Blood-Cerebrospinal Fluid Barrier

Despite the existence of two barrier systems in the brain research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus and then covers various aspects of its function such as the regulation of choroidal blood flow ion transport and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders the final section discusses in vitro in vivo and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience pharmacology and toxicology.

GBP 39.99
1

Red Blood Cell Aggregation

Red Blood Cell Aggregation

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology similar to a stack of coins. Known as rouleaux these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic clinical and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants mechanisms and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field this is an invaluable resource for basic science medical and clinical researchers; graduate stu

GBP 59.99
1

Controlling High Blood Pressure through Nutrition Supplements Lifestyle and Drugs

Controlling High Blood Pressure through Nutrition Supplements Lifestyle and Drugs

Controlling High Blood Pressure through Nutrition Nutritional Supplements Lifestyle and Drugs helps prevent and treat high blood pressure and hypertension the most common primary diagnosis in the United States and a leading cause of heart attack heart failure kidney failure and stroke. Written by two leading experts in nutrition and hypertension it takes an integrative and evidence-based approach based on scientific research and clinical studies. It explains what causes high blood pressure and includes easy-to-follow solutions for patients that help to treat and prevent it. These include: The ideal drugs to reduce blood pressure with fewest side effects and optimal efficacy A nutrition program to reduce weight and lower the risk of a cardiovascular problem A comprehensive review of nutritional supplements to improve blood pressure control and reduce cardiovascular disease A review of lifestyle changes to improve blood pressure such as a detailed exercise program. This book is for doctors nutritionists naturopaths pharmacists and other health practitioners as well as anyone with a family history of hypertension or overt blood pressure issues that would like to make better and healthier lifestyle choices. | Controlling High Blood Pressure through Nutrition Supplements Lifestyle and Drugs

GBP 52.99
1

The Blood-Brain Barrier in Health and Disease Volume Two Pathophysiology and Pathology

The Blood-Brain Barrier in Health and Disease Volume Two Pathophysiology and Pathology

Located at the interface between blood and the brain the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability transport and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Abnormalities of the blood-brain barrier are increasingly recognized as a key component in the pathogenesis of a range of primary diseases of the brain and the secondary involvement of the brain from pathological processes in other organs. In The Blood-Brain Barrier in Health and Disease Volume 2 international experts present comprehensive reviews and research accounts on blood-brain barrier dysfunction in infectious and inflammatory diseases cerebrovascular diseases stroke trauma vitamin deficiency exposure to neurotoxicants primary and metastatic brain tumors and neurodegenerative diseases. This book is intended to serve as a guide and reference to basic and advanced information for researchers students and clinicians interested in this fast-expanding field and stimulate further research well into the future. | The Blood-Brain Barrier in Health and Disease Volume Two Pathophysiology and Pathology

GBP 44.99
1

The Blood-Brain Barrier in Health and Disease Volume One Morphology Biology and Immune Function

The Blood-Brain Barrier in Health and Disease Volume One Morphology Biology and Immune Function

Located at the interface between blood and the brain the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability transport and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Over the last 25 years we have witnessed remarkable expansion of our knowledge of the structure biology and function of the cerebral endothelium. In The Blood-Brain Barrier in Health and Disease Volume 1 international experts discuss basic and new concepts and most recent advances pertaining to the development of the cerebral microvascular system. Subjects include the structure function permeability properties transport mechanisms and the inherent heterogeneity of the cerebral endothelium; the anatomy and physiological properties of the neurovascular unit; functional aspects of the choroid plexus; and important concepts and advances made over the last two decades that have shaped our understanding of the immunological function of the blood-brain barrier. This book is intended to serve as a valuable source of basic and advanced information for researchers students and clinicians interested in this fast-expanding field and stimulate further research well into the future. | The Blood-Brain Barrier in Health and Disease Volume One Morphology Biology and Immune Function

GBP 44.99
1

Diagnostic Ultrasound Imaging and Blood Flow Measurements Second Edition

Diagnostic Ultrasound Imaging and Blood Flow Measurements Second Edition

Offers an Extensive Discussion on High Frequency Ultrasound Based on a course taught and developed by a foremost expert in diagnostic ultrasound technology Diagnostic Ultrasound: Imaging and Blood Flow Measurements Second Edition covers cutting-edge developments along with the fundamental physics instrumentation system architecture clinical applications and biological effects of ultrasound. This text addresses the technical side of diagnostic ultrasound and begins with an overview of the field of ultrasonic imaging and its role in diagnostic medicine relative to other imaging modalities. The author describes the fundamental physics involved in ultrasonic transducers as well as in conventional imaging approaches and Doppler measurements including contrast imaging and 4D imaging. He reviews the current status and standards on ultrasound bioeffect and discusses methods that have been used to measure ultrasonic properties of tissues. He also provides a list of relevant references and further reading materials at the end of each chapter. New in the Second Edition: Details the latest advances in ultrasound technology related to biomedical applications including elastrography portable scanners ultrasound molecular imaging preclinical high frequency imaging 2D array and 4D imaging techniques Updates and expands each chapter Adds a new chapter on new developments such as elastography and miniature scanners Includes new case studies and examples throughout the book Diagnostic Ultrasound: Imaging and Blood Flow Measurements Second Edition covers recent advances in ultrasound technology related to biomedical applications. Intended for senior- to graduate-level coursework in ultrasonic imaging this text also serves practicing physicists engineers clinicians and sonographers. | Diagnostic Ultrasound Imaging and Blood Flow Measurements Second Edition

GBP 74.99
1

Outpatient Nutrition Care: GI Metabolic and Home Nutrition Support Practical Guidelines for Assessment and Management

Outpatient Nutrition Care: GI Metabolic and Home Nutrition Support Practical Guidelines for Assessment and Management

As the number of patients receiving home care nutrition support increases proper assessment and management of this therapy is crucial and clinicians need to practice at an advanced level. This second edition provides practical nutrition care information for professionals working with individuals outside of the hospital including registered dietitians nurses pharmacists and physicians. It covers screening assessing and treating malnutrition; outpatient nutrition care in diabetes cardiovascular disease gastrointestinal disease and home enteral and parenteral nutrition. Each chapter describes the disease process as well as the management of the disease or therapy. Key Features Presents practical information on proper nutrition care of individuals in the outpatient setting and those receiving home nutrition support New information on GI tests and procedures; gastroparesis/pancreatitis parenteral lipids and bariatric surgery Expanded chapter on short bowel syndrome and malabsorptive disorders Additional information on feeding options including an overview of oral oral supplements and enteral and parenteral nutrition Teaches the user additional information on disease processes as well as the management of the disease or therapy | Outpatient Nutrition Care: GI Metabolic and Home Nutrition Support Practical Guidelines for Assessment and Management

GBP 44.99
1

Extremophiles From Biology to Biotechnology

Extremophiles From Biology to Biotechnology

Highly recommended by CHOICE Oct 2018Extremophiles are nature’s ultimate survivors thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents. Their lifeforms span bacteria to fishes and are categorized as halophiles from hypersaline environments acidophiles from acidic waters psychrophiles from cold habitats and thermophiles from warm waters. Extremophiles: From Biology to Biotechnology comprehensively covers the basic biology physiology habitats secondary metabolites for bioprospecting and biotechnology of these extreme survivors. The chapters focus on the novel genetic and biochemical traits that lend these organisms to biotechnological applications. Couples studies of marine extremophile biology/genomics and extremophile culture for biotechnological applications with the latest advances in bio-prospecting and bio-product developmentIncludes practical experiments that a laboratory can use to replicate extreme habitats for research purposesPresents latest advances in extremophile genomics to give the reader a better understanding of the regulatory mechanisms of extremophilesOffers insights into the production of commercially important extremozymes carotenoids bioactive compounds and secondary metabolites of medicinal value. This unique guide serves as a resource for biotechnologists who wish to explore extremophiles for their commercial potential as well as a valuable reference for teaching undergraduate graduate and postgraduate students. | Extremophiles From Biology to Biotechnology

GBP 48.99
1

Animation From Concepts and Production

Animation From Concepts and Production

This book explains the creation of animation from concept to production. Instead of focusing on singular aspects of animation production talented animators can learn to make better films by understanding the process as a whole. Veteran independent filmmaker Hannes Rall teaches you how to develop an animation project from the very start of conceptual exploration though to completed production. Subjects like script storyboarding character and production design illuminate the pre-production process; later chapters explain the production process applied to different animation techniques like 2D animation 3D computer animation and stop motion. This book is just the right mix of practical advice lavish illustrations and industry case studies to give you everything you need to start creating animation today. Key Features Learn the concepts of film animation production from an expert instructor Interviews with legends Andreas Deja Hans Bacher and Volker Engel Robust coverage of the pre-production process from script to storyboarding and visual development Includes a glossary and further reading recommendations | Animation From Concepts and Production

GBP 42.99
1

Hydroponics for the Home Grower

Hydroponics for the Home Grower

Hydroponics offers many advantages to traditional soil-based horticulture. These include greater control over many of the limiting factors such as light temperature and pests as well as the ability to grow plants in all seasons. With instruction from one of the top recognized authorities worldwide Hydroponics for the Home Grower gives you step-by-step guidance on how to grow tomatoes peppers cucumbers eggplant lettuce arugula bok choy and various herbs year-round within your home or in a backyard greenhouse. Read an Interview with Dr. Resh here With Dr. Howard Resh‘s help you‘ll learn: Background information on how hydroponics evolved The nutritional and environmental demands of plants and how to control these factors How to provide formulations of nutrients optimal to the plants you wish to grow The many different hydroponic systems you can purchase or build for yourself Designs for different types of greenhouses with components to fit your personal taste and budget Crop selection and step-by-step procedures including seeding transplanting training pest and disease control and harvesting along with when to plant and when to change crops How you can grow microgreens on your kitchen counter The book includes an appendix with sources of seeds and other supplies along with helpful websites and lists of books articles and conferences on growing hydroponically and caring for your crops. By following the guidelines in this book you‘ll understand everything you need to know to get your home-growing operation up and running in no time.

GBP 180.00
1

Kava From Ethnology to Pharmacology

Kava From Ethnology to Pharmacology

Kava is an herb that has been used for ceremonial ritual religious social political and medicinal purposes for centuries. In the past few decades kava has been widely marketed as an over-the-counter treatment for anxiety stress restlessness and sleep disorders. Kava: From Ethnology to Pharmacology describes the history botanical origins production economic aspects and chemical and biological properties of this medicinal herb. A major part of the book focuses on the chemical and pharmacological properties of kavalactones the psychoactive constituents of kava that reportedly have sedative anxiolytic analgesic local anesthetic anticonvulsant and neuroprotective properties. Clinical and medical studies that provide evidence of kava's therapeutic benefits are balanced with an assessment of the known adverse effects and interactions in which kava has been implicated. With contributions from experts in the field this volume presents a comprehensive view of the traditional aspects of kava and the latest applications for the herb. It is a valuable reference for botanists phytochemists toxicologists physicians pharmacists herbalists and alternative medicine practitioners. | Kava From Ethnology to Pharmacology

GBP 56.99
1

Numerical Modeling of COVID-19 Neurological Effects ODE/PDE Analysis in R

Numerical Modeling of COVID-19 Neurological Effects ODE/PDE Analysis in R

Covid-19 is primarily a respiratory disease which results in impaired oxygenation of blood. The O2-deficient blood then moves through the body and for the study in this book the focus is on the blood flowing to the brain. The dynamics of blood flow along the brain capillaries and tissue is modeled as systems of ordinary and partial differential equations (ODE/PDEs). The ODE/PDE methodology is presented through a series of examples 1. A basic one PDE model for O2 concentration in the brain capillary blood. 2. A two PDE model for O2 concentration in the brain capillary blood and in the brain tissue with O2 transport across the blood brain barrier (BBB). 3. The two model extended to three PDEs to include the brain functional neuron cell density. Cognitive impairment could result from reduced neuron cell density in time and space (in the brain) that follows from lowered O2 concentration (hypoxia). The computer-based implementation of the example models is presented through routines coded (programmed) in R a quality open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized e. g. no theorems and proofs. Rather the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The PDE analysis is based on the method of lines (MOL) an established general algorithm for PDEs implemented with finite differences. The routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the blood/brain hypoxia models such as changes in the ODE/PDE parameters (constants) and form of the model equations. | Numerical Modeling of COVID-19 Neurological Effects ODE/PDE Analysis in R

GBP 82.99
1

Cancer Inhibitors from Chinese Natural Medicines

Cancer Inhibitors from Chinese Natural Medicines

Nature is an attractive source of therapeutic and preventive compounds and with such chemical diversity found in millions of species of plants over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new advancements in the experimental and clinical research of a selection of promising cancer inhibitors. It focuses on the latest scientific investigations of 238 Chinese herbs and discusses important aspects including the types of inhibitors in the herbs level of potency mechanisms and the advances in modification and formulation. Formulations from nano-particulates and immunotoxins in cancer inhibitors are also included in this comprehensive resource.

GBP 44.99
1

Nanotherapeutics From Laboratory to Clinic

Nanotherapeutics From Laboratory to Clinic

The emergence of nanotherapeutics is attributable to the integration of nanotechnology recombinant DNA technology and synthetic organic chemistry with medicine for treating critical human diseases in a more efficient and specific molecular approach than therapy with conventionally-designed and formulated drugs. Nanotherapeutics: From Laboratory to Clinic comprehensively discusses the current shortcomings for delivery of classical (small) drugs macromolecular therapeutics and recombinant vaccine via the common intravascular and extravascular routes. The book describes the synthetic/chemical engineering methods as well as recombinant hybridoma and phage display technologies to fabricate different types of nanoparticulate carriers and drugs. It also reveals the diversified approaches undertaken by harnessing nanotechnology to overcome the multistep extracellular and intracellular barriers and to facilitate the development of novel strategies for therapeutic delivery and imaging. The author elaborates on the preclinical and clinical trials of potential nanoparticle-based products in animal models and patients and the approval/commercialization of nanotherapeutics addressing all relevant human diseases. A focus on the above issues in a concise but illustrative manner fills the gap between the laboratory findings originating from the research on identification of cellular and systemic barriers of classical and macromolecular drugs along with development of strategies for fabrication and testing of nanotherapeutics and the clinical outcomes emanating from the testing of the selected potential nanotherapeutics on patients of particular diseases. The book also fills a gap in the existing literature between the design and development of diversified nanotherapeutics for various purposes and the investigation and evaluation of potential barriers and resultant therapeutic efficacy of those nano-medicine formulations. | Nanotherapeutics From Laboratory to Clinic

GBP 44.99
1

Energy from Waste Production and Storage

Energy from Waste Production and Storage

Conversion of waste into value-added products such as energy transforms a potential environmental problem into a sustainable solution. Energy from Waste: Production and Storage focuses on the conversion of waste from various sources for use in energy production and storage applications. It provides the state-of-the-art in developing advanced materials and chemicals for energy applications using wastes and discusses the various treatment processes and technologies. Covers synthesis of usable materials from various types of waste and their application in energy production and storage Presents an overview and applications of wastes for green energy production and storage Provides fundamentals of electrochemical behavior and understanding of energy devices such as fuel cells batteries supercapacitors and solar cells Elaborates on advanced technologies used to convert waste into green biochemical energy This work provides new direction to scientists researchers and students in materials and chemical engineering and related subjects seeking to sustainable solutions to energy production and waste management. | Energy from Waste Production and Storage

GBP 150.00
1

Structural Design from First Principles

Structural Design from First Principles

This enlightening textbook for undergraduates on civil engineering degree courses explains structural design from its mechanical principles showing the speed and simplicity of effective design from first principles. This text presents good approximate solutions to complex design problems such as Wembley-Arch type structures the design of thin-walled structures and long-span box girder bridges. Other more code-based textbooks concentrate on relatively simple member design and avoid some of the most interesting design problems because code compliant solutions are complex. Yet these problems can be addressed by relatively manageable techniques. The methods outlined here enable quick early stage ball-park design solutions to be considered and are also useful for checking finite element analysis solutions to complex problems. The conventions used in the book are in accordance with the Eurocodes especially where they provide convenient solutions that can be easily understood by students. Many of the topics such as composite beam design are straight applications of Eurocodes but with the underlying theory fully explained. The techniques are illustrated through a series of worked examples which develop in complexity with the more advanced questions forming extended exam type questions. A comprehensive range of fully worked tutorial questions are provided at the end of each section for students to practice in preparation for closed book exams. | Structural Design from First Principles

GBP 48.99
1

Environmental Exposure From Chemicals Volume II

Environmental Exposure From Chemicals Volume II

This two-volume series will describe the mechanisms that are operating on chemicals as thy move in the environment. Knowledge of these mechanisms is a vital component in performing a risk assessment. Volume I will deal with the physical and chemical properties of a material and how these influence the degradation and dissipating reactions. Volume 2 will address the transport of the chemical as it moves through the environment from the source to the final sink. | Environmental Exposure From Chemicals Volume II

GBP 140.00
1

Rehabilitation from COVID-19 An Integrated Traditional Chinese and Western Medicine Protocol

Rehabilitation from COVID-19 An Integrated Traditional Chinese and Western Medicine Protocol

The COVID-19 pandemic is unlike anything the world has ever seen before. Its reach is wide and its effects have been debilitating. Understanding this particular strain of the coronavirus and knowing the best ways to recover are more important than ever. Rehabilitation from COVID-19: An Integrated Traditional Chinese and Western Medicine Protocol contains basic knowledge about COVID-19 including its etiology pathogenesis and treatment both in traditional Chinese medicine and Western medicine. It also includes relative assessment and rehabilitation targeting residual dysfunctions due to COVID-19 such as pulmonary dysfunction mental disorders and malnutrition among others. Key Features Presents a new concept of CRN (COVID-19 Rehabilitation Unit) that will protect patients and medical workers Emphasizes special management of rehabilitation procedures under COVID-19 conditions Includes home-based rehabilitation tactics Provides assessment scales to help patients self-evaluate Based on clinical experience from experts this text has been compiled by those on the frontline against COVID-19 in Wuhan. Rehabilitation from COVID-19 is an informative collection that will be helpful to patients and medical workers alike. | Rehabilitation from COVID-19 An Integrated Traditional Chinese and Western Medicine Protocol

GBP 66.99
1

Magnetic Nanoparticles From Fabrication to Clinical Applications

Magnetic Nanoparticles From Fabrication to Clinical Applications

Offering the latest information in magnetic nanoparticle (MNP) research Magnetic Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review from synthesis characterization and biofunctionalization to clinical applications of MNPs including the diagnosis and treatment of cancers. This book written by some of the most qualified experts in the field not only fills a hole in the literature but also bridges the gaps between all the different areas in this field. Translational research on tailored magnetic nanoparticles for biomedical applications spans a variety of disciplines and putting together the most significant advances into a practical format is a challenging task. Balancing clinical applications with the underlying theory and foundational science behind these new discoveries Magnetic Nanoparticles: From Fabrication to Clinical Applications supplies a toolbox of solutions and ideas for scientists in the field and for young researchers interested in magnetic nanoparticles. | Magnetic Nanoparticles From Fabrication to Clinical Applications

GBP 77.99
1

Multiscale Modeling From Atoms to Devices

Multiscale Modeling From Atoms to Devices

While the relevant features and properties of nanosystems necessarily depend on nanoscopic details their performance resides in the macroscopic world. To rationally develop and accurately predict performance of these systems we must tackle problems where multiple length and time scales are coupled. Rather than forcing a single modeling approach to predict an event it was not designed for a new paradigm must be employed: multiscale modeling. A brilliant solution to a pervasive problem Multiscale Modeling: From Atoms to Devices offers a number of approaches for which more than one scale is explicitly considered. It provides several alternatives from coarse-graining sampling of the atomic and mesoscale to Monte Carlo- and thermodynamic-based models that allow sampling of increasingly large scales up to multiscale models able to describe entire devices. Beginning with common techniques for coarse-graining the book discusses their theoretical background advantages and limitations. It examines the application-dependent parameterization characteristics of coarse-graining along with the finer-trains-coarser multiscale approach and describes three carefully selected examples in which the parameterization although based on the same principles depends on the actual application. The book considers the use of ab initio and density functional theory to obtain parameters needed for larger scale models the alternative use of density functional theory parameters in a Monte Carlo method and the use of ab initio and density functional theory as the atomistic technique underlying the calculation of thermodynamics properties of alloy phase stability. Highlighting one of the most challenging tasks for multiscale modelers Multiscale Modeling: From Atoms to Devices also presents modeling for nanocomposite materials using the embedded fiber finite element method (EFFEM). It emphasizes an ensemble Monte Carlo method to high field-charge transport problems and demonstrates the practical application of modern many-body quantum theories. The author maintains a website with additional information. | Multiscale Modeling From Atoms to Devices

GBP 69.99
1