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Forensic DNA Transfer

Forensic DNA Transfer

Forensic DNA Transfer provides a guide to the recognition and current understanding of DNA transfer in forensic criminal investigations. Increased improvements in technology mean that it is now routinely possible to obtain DNA profiles from non-visible deposits. How or when the DNA in question was deposited may be an issue in the context of the case especially if the donor of the DNA is not in dispute. A DNA profile alone cannot reveal when or how that DNA was deposited at a crime scene nor can it reveal the body matter from which it originated. Issues of transfer associated with activities may be debated—which the traditional discrimination purpose of DNA profiling cannot address. DNA may be everywhere and anywhere—in homes at workplaces during transport and on personal items including clothing. DNA from a person may be on an object they have never contacted or in a room they have never entered. Concepts discussed in the book include non-self DNA on hands through day-to-day activities the prevalence of background DNA in the environment and perhaps on the exhibit the persistence of any DNA transferred and that a DNA result will depend on these variables as well as recovery techniques. Since DNA may be transferred to an exhibit: (a) during the commission of a crime (b) before the crime and/or (c) after the crime through handling examination and testing this book covers various transfer pathways and sources of DNA. Documented cases of inadvertent transfer of DNA resulting in wrongful convictions or the misdirection of criminal investigations are discussed—with an emphasis on contamination mitigation throughout the entire process. Forensic DNA Transfer examines the additional complexity resulting from non-visible deposits of DNA that impact on sampling and testing regimes. The changing understanding of the composition of purported 'touch DNA' deposits from the skin including extracellular DNA transported via body secretions is described. Further the newer focus on interpreting DNA evidence—using activity level propositions and the rationale and associated issues—is also discussed.

GBP 46.99
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Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications: An Interdisciplinary Perspective Second Edition is fully updated to outline the latest advances in forensic DNA testing techniques and applications. It continues to fill the need for a reference book for people working in the field of forensic molecular biology testing and research as well as individuals investigating and adjudicating cases involving DNA evidence whether they be civil or criminal cases. DNA techniques have greatly impacted obvious traditional forensic areas but such advances have also positively affected myriad new areas of research and inquiry. It is possible today to think about solving forensic problems that were simply unheard of even a few years ago. As such the book pulls all relevant research and applied science together into a detailed and comprehensive collection. Part I begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples mitochondrial DNA testing Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs) and X SNP and STR testing. It also explores low copy number DNA typing mixtures and quality assurance and control. Part II moves on to cover the various uses and applications of analyzing collected physical evidence victim identification in mass disasters analyzing animal DNA forensic botany and other unique applications. Part III is dedicated to the latest advances and developments in human molecular biology and Part IV looks at policies and laws and ethics governing DNA evidence and its utilization in various cases and the courts. Forensic DNA Applications Second Edition covers cutting-edge research and advancements in the field and is the most up-to-date reference available. Edited and contributed to by the world's foremost leaders in the field it is a must-have reference for established professionals and an essential resource to legal professionals—lawyers and judges dealing with civil and criminal cases involving DNA technology—as well as students entering the fields of genetics and forensic DNA analysis. | Forensic DNA Applications An Interdisciplinary Perspective

GBP 56.99
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DNA Nanoscience From Prebiotic Origins to Emerging Nanotechnology

DNA Nanoscience From Prebiotic Origins to Emerging Nanotechnology

DNA Nanoscience: From Prebiotic Origins to Emerging Nanotechnology melds two tales of DNA. One is a look at the first 35 years of DNA nanotechnology to better appreciate what lies ahead in this emerging field. The other story looks back 4 billion years to the possible origins of DNA which are shrouded in mystery. The book is divided into three parts comprised of 15 chapters and two Brief Interludes. Part I includes subjects underpinning the book such as a primer on DNA the broader discipline of nanoscience and experimental tools used by the principals in the narrative. Part II examines the field of structural DNA nanotechnology founded by biochemist/crystallographer Nadrian Seeman that uses DNA as a construction material for nanoscale structures and devices rather than as a genetic material. Part III looks at the work of physicists Noel Clark and Tommaso Bellini who found that short DNA (nanoDNA) forms liquid crystals that act as a structural gatekeeper orchestrating a series of self-assembly processes using nanoDNA. This led to an explanation of the polymeric structure of DNA and of how life may have emerged from the prebiotic clutter. | DNA Nanoscience From Prebiotic Origins to Emerging Nanotechnology

GBP 180.00
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Artificial DNA Methods and Applications

Artificial DNA Methods and Applications

Combining elements of biochemistry molecular biology and immunology artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis hybridization amplification protein engineering anti-sense technology DNA vaccines protein vaccines recombinant antibodies screening for genetic and pathogenic diseases development of materials with new biochemical and structural properties and many more. Artificial DNA: Methods and Applications introduces the concept of artificial DNA that has been rationally designed and explains how it may be exploited in order to develop products that will achieve your intended purpose. The first part of the book covers methods of oligonucleotide synthesis and direct applications of synthetic DNA. The second part describes methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. The authors also discuss the different trends and future developments within each application area . With state-of-the art research the contributing authors describe how to engineer proteins using rational and semi-rational design to exhibit the desired traits and detail the various amplification reactions and hybridization techniques for modeling evolution and for use in basic research. The only text devoted to this subject Artificial DNA offers a comprehensive review that allows you to understand the strategy design and applications of synthetic oligonucleotides. | Artificial DNA Methods and Applications

GBP 59.99
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Forensic DNA Analysis Current Practices and Emerging Technologies

Forensic DNA Analysis Current Practices and Emerging Technologies

The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing forensic casework family lineage studies identification of human remains and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize document collect and store it. The remaining chapters examine:The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remainsStudies carried out on the use of both messenger RNA and small (micro) RNA profilingReal-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotypingCapillary electrophoresis (CE) as a tool for forensic DNA analysisNext-generation short tandem repeat (STR) genotyping kits for forensic applications the biological nature of STR loci and Y-chromosome STRs (Y-STRs)Mitochondrial DNA (mtDNA) sequence analysisSingle nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in typing highly degraded DNADeep-sequencing technologiesThe current state of integrated systems in forensic DNA analysis The book concludes by discussing various aspects of sample-processing training and the entities that provide such training programs. This volume is an essential resource for students researchers teaching faculties and other professionals interested in human identification/forensic DNA analysis. | Forensic DNA Analysis Current Practices and Emerging Technologies

GBP 77.99
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Introduction to Forensic DNA Evidence for Criminal Justice Professionals

Introduction to Forensic DNA Evidence for Criminal Justice Professionals

The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting yet for those with limited scientific knowledge understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed for nonscientific readers who need to learn how to effectively use forensic DNA in criminal cases. Written by a forensic scientist world renowned for her expertise in clothing examination the book provides a balanced perspective on the weight of DNA evidence. Going beyond a simple explanation of the methodology it arms attorneys and other criminal justice professionals with knowledge of the strengths and limitations of the evidence including the danger in relying on DNA statistical probabilities in the determination of guilt. The book covers the most common DNA methods used in criminal trials today nuclear DNA short tandem repeat (STR) techniques mitochondrial DNA and Y-STR profiling. It helps prosecutors know when to emphasize DNA evidence or proceed with trial in the absence of such evidence. It assists defense lawyers in knowing when to challenge DNA evidence and perhaps employ an independent expert when to focus elsewhere or when to secure the advantage of an early guilty plea. By imparting practical and theoretical knowledge in an accessible manner the book demystifies the topic to help both sides of the adversarial system understand where DNA evidence fits within the context of the case.

GBP 180.00
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Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures how to assign a likelihood ratio and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods the polymerase chain reaction (PCR) capillary electrophoresis (CE) likelihood ratios (LRs) and their interpretation and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES:• The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods heretofore unpublished previously provide a means to innovate deconvoluting a mixed DNA profile assign an LR and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i. e. “It’s not me it was my brother”) and discusses strategies for the validation of probabilistic genotyping softwareForensic DNA Profiling fills the void for labs unfamiliar with LRs and moving to probabilistic solutions and for labs already familiar with LRs but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians students and legal professionals seeking to understand and apply the techniques covered. | Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

GBP 44.99
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Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

A powerful tool in the identification of individuals DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories Forensic Analysis of Biological Evidence: A Laboratory Guide for Serological and DNA Typing introduces readers to the science of serological analysis and DNA typing methods and provides a thorough background of the molecular techniques used to determine an individual‘s identity or parental lineage. Originally published as Forensic DNA Analysis: A Laboratory Manual this revised work offers updated exercises and protocols for all kinds of DNA and serological analyses with delineated objectives step-by-step procedures and required laboratory supplies. Each exercise in this manual: Provides an overview of forensic DNA analysis Explains the sources or types of biological material used in a particular DNA analysis Supplies the background principles and practical methodology for specific serological analysis and DNA typing techniques Simulates human forensic testing and can also be used to simulate a wide range of applications for genetic analysis The book contains an extensive glossary to make readers familiar with terminology used in the forensic analysis of biological evidence as well as basic terms used in molecular biology. Those who master the material in this volume will understand the methodology of the investigation in DNA typing develop an understanding of the scientific principles involved in serology and DNA analysis and succeed in analyzing and interpreting the data generated in each exercise with clarity and confidence. | Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

GBP 180.00
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Rotating Machinery Research and Development Test Rigs

Rotating Machinery Research and Development Test Rigs

Rotating Machinery Research and Development Test Rigs presents the purpose and development processes for test apparatuses built for Research & Development in machinery technology and product development. Each R & D apparatus is the focus of an entire chapter with fifteen detailed case studies included from mechanical aerospace chemical and biomedical engineering. Specific machinery components covered include bearings seals power plant pumps rotors turbines and compressors. Machinery condition monitoring and product development processes have been integrated. The specific purpose and results for each test rig are comprehensively presented and explained.

GBP 150.00
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Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs: From Science to Scene Second Edition is designed to help canine handlers detectives death investigators crime scene personnel (including forensic laboratory personnel technicians and supervisors) and attorneys understand the science involved when utilizing human remains detector (HRD) canines as a locating tool. The book covers the basic anatomy and physiology of canine olfaction and the unique characteristics of their scenting ability that allows dogs to be trained to locate distinct odors. Using concise and clear explanations and photographs the book reviews the science of forensic taphonomy. Factors that may affect the decomposition process are highlighted along with what the potential outcomes that may be encountered. The book examines how the odor of human remains is generated through various stages of decomposition and the manner in which environmental conditions in both land and water settings may affect that odor. Different types of background information that may help in determining possible search locations for missing individuals are included as well as assist the HRD canine handler in developing search plans are covered. Different tools and technologies that may be used in addition to an HRD canine team are included to help readers understand that are many ways to address searching for a decedent. Several case reports involving decedents found in both land and water settings in addition to different weather conditions are included to help the reader understand how the environment may have affected the condition of the decedent. This edition includes more case reports explaining how environmental factors were considered in HRD canine deployments in both land and water settings. Understanding which variables—and how such variables—can affect the state and condition of human remains as well as dispersion of odor from human remains will help canine handlers utilize their HRD canine more effectively as a locating tool. Death Decomposition and Detector Dogs Second Edition will help HRD canine handlers and other law enforcement personnel be better prepared to meet the challenges of their jobs before during and after searches for the missing. | Death Decomposition and Detector Dogs From Science to Scene

GBP 42.99
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Psoralen Dna Photobiology Volume I

Psoralen Dna Photobiology Volume I

In one form or another psoralens have been in use dating back to biblical times for the treatment of depigmented patches of skin. However it has only been in the past 40 years that the structure and function of psoralens have been elucidated. Although several volumes have been published on photobiology and photomedicine no one volume has ever been devoted to the psoralen photobiology. In these two volumes we focus on the properties and uses of photoactivated psoralens. In these volumes the various aspects of psoralens are presented in a review of the field as it stands in mid 1986. In retrospect we may find that this particular time was crucial in the development of new therapeutic modalities as many of the applications of modem molecular biology are beginning to impact on the practice of medicine. This book was written with two purposes in mind. First to serve as an update (the last collective review of the field was in 1982). Second it is hoped that newcomers to the fields of photobiology andphotomedicine both scientists and clinicians would find it a useful introduction. | Psoralen Dna Photobiology Volume I

GBP 89.99
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Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

Dogs detect scent from a source that is carried to them in a plume by the wind. The most important tool for a detector dog handler to have on searches is a knowledge of scent plume movement or scent dynamics (the science of scent movement). Such knowledge resides primarily in scientific journals that are largely inaccessible to detector dog handlers and written in language that is difficult to understand. Detector Dogs and the Science of Scent Movement: A Handler’s Guide to Environments and Procedures retrieves reviews and interprets the results of pertinent scientific research on scent dynamics and presents these results in terms that are easier for handlers to understand. Information on the physiology of the dog’s nose their sense of smell and the properties of scent provide the essential information on the process of scenting. The composition of training aids for explosives narcotics human remains and other sources is discussed. Recommendations are made on the use of training aids their placement during training and the resulting availability of scent. Potential problems and handler errors in the use of training aids are also examined. The characteristics of scent plumes and how wind influences their movement are a key focus of the book. The primary task for the handler is to get the dog into the scent plume so that the dog can detect the scent and follow it to the source the handler seeks. As such a knowledge of scent and scent plume movement will vastly improve the ability of the handler to accomplish this task. The influence of weather and physical settings such as terrain vegetation ground cover soil and water on scent movement are examined in detail. Strategies for searching detecting and locating sources in all physical settings are presented. Specific effects associated with hills and mountains fields and forests bare soils and soils covered by vegetation different soil types and lakes and rivers are examined in detail. This includes specific recommendations are made about weather and physical settings that result in higher probability of success on searches. Detector Dogs and the Science of Scent Movement will be a vital resource for K9 handles in the private and public sectors—including in Homeland Security law enforcement and military settings—as well as a useful guide for lawyers forensic and investigative professionals who need to better understand K9 operations. | Detector Dogs and Scent Movement How Weather Terrain and Vegetation Influence Search Strategies

GBP 44.99
1

Test Quality for Construction Materials and Structures Proceedings of the International RILEM/ILAC Symposium

Test Quality for Construction Materials and Structures Proceedings of the International RILEM/ILAC Symposium

Testing of materials and manufactured items is a key element in the process from standard specifications though control and verification during manufacture to trade in actual products. Cooperative agreements and networks are being set up covering reference materials and calibration. This process is becoming more urgent with the development in the European market and other international developments. This book presents international views on this fast changing field with the main themes of: technical components of test quality; quality assurance in testing laboratories; laboratory accreditation and transnational recognition of test results. | Test Quality for Construction Materials and Structures Proceedings of the International RILEM/ILAC Symposium

GBP 62.99
1

Diagnostic MRI in Dogs and Cats

Diagnostic MRI in Dogs and Cats

Diagnostic MRI in Dogs and Cats makes the vast and increasingly complex topic of clinical MRI in small animals accessible to all veterinarians. With the increasing availability of MRI technology there is also a pressing need for expertise in interpreting these images. This is the first reference textbook to provide a well-illustrated and comprehensive overview of the current knowledge focusing on imaging appearance rather than on clinical signs or treatment. With chapters on MRI physics and technology as well as sections on specific anatomical regions the book functions as a stand-alone reference for the reader whether they be a radiology/neurology resident in training or a practitioner with a need to learn about veterinary clinical MRI. Includes both evidenced-based material and the authors' personal experience providing an excellent overview of current knowledge in the field. Contributors are international leaders in the field. Bullet points format and table summaries throughout the book keep the concepts concise and organized. Richly illustrated with over 650 annotated images showcasing the main features of the disease processes. Images are obtained at all magnet field strengths so as to reflect the current reality of veterinary MRI which uses low- mid- and high-field magnets. The chapters on physics and MRI technology are concise and accessible using many visual aids and diagrams and avoiding abstract concepts and equations whenever possible. Within each anatomical section each chapter focuses on a disease category of that body region. When it is important to understand the imaging appearance the pathophysiology is reviewed and imaging features of prognostic relevance are detailed. This practical yet thoroughly comprehensive book is primarily an evidence-based learning resource for trainees but will also aid practising veterinarians who have less MRI experience.

GBP 240.00
1

Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing chromosome aberrations and mutations before exploring organ damage organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics biomedical engineering radiological protection medicine radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy | Understanding Radiation Biology From DNA Damage to Cancer and Radiation Risk

GBP 94.99
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PgMP Exam Practice Test and Study Guide

PgMP Exam Practice Test and Study Guide

PgMP Exam Practice Test and Study Guide Fourth Edition is the book you need to pass the Program Management Professional (PgMP) exam the first time around. It reflects recent revisions based on PMI's Standard for Program Management - Third Edition (2013). Based on best practices that complement PMI‘s standards this is the most comprehensive and up-to-date resource available to help you prepare for the exam with new and changed terminology. It includes a list of the major topics covered on the exam organized by the five performance domains‘strategic program management program life cycle benefits management stakeholder management and governance as presented in the Program Management Professional Examination Content Outline. It also includes helpful tips on how to make the most of the time you have available to prepare for the exam. Just like its bestselling predecessors this indispensable study guide includes 20 multiple-choice practice questions for each domain along with a comprehensive answer key. The program life cycle domain includes 20 questions for each of the five phases. Each question also has a plainly written rationale for each correct answer with bibliographic references for further study. Two challenging 170-question practice tests that simulate the actual exam are included in the book and online so you can retake them as many times as necessary. They also include a rationale and reference. Scores for the online tests are presented as if each question is rated similarly but this edition also includes a new component: the authors own weighting system for the level of difficulty for each question. This system will show you what they feel meets the exam‘s criteria for Proficient Moderately Proficient and below Proficient. You then will see your scores by domain in both approaches. Supplying an in | PgMP® Exam Practice Test and Study Guide

GBP 175.00
1

Engineered Concrete Mix Design and Test Methods Second Edition

Engineered Concrete Mix Design and Test Methods Second Edition

As every civil engineer knows Portland Cement is the most versatile and important material of construction and will probably remain so far into the future. Yet few books if any exist that offer an in-depth analysis of the mixing and testing methods of this vital hydraulic cement. This statement written about the first edition of Engineered Concrete: Mix Design and Test Methods remains as true today as it was ten years ago. Revised and updated the second edition of this groundbreaking resource completely covers Portland Cement Portland Cement Concrete and their uses. See what‘s new in the Second Edition: New coverage of the latest concrete technologies such as high-performance and lightweight concrete Several new tests and sample tearsheets Additional and updated data sheets The body of the book is divided into several sections with the first explaining how concrete batches are designed mixed and measured for various consistencies. Another section details the tests of the primary component materials of concrete other than water namely Portland Cement aggregates and mortar while the final section includes some of the fundamental concrete testing procedures for different strength parameters in conformity with the standards of the American Society for Testing Materials. Solidly researched and written the book supplies a fundamental understanding of cement concrete and mixing and testing methods that allow readers to produce the most economical combinations of concrete materials and satisfy performance requirements and specifications. | Engineered Concrete Mix Design and Test Methods Second Edition

GBP 180.00
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Handbook of Mitochondrial Dysfunction

Handbook of Mitochondrial Dysfunction

Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key FeaturesPresents the detailed structure of mitochondria mitochondrial function roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseasesExplores a wide variety of diseases caused by dysfunctional mitochondria. | Handbook of Mitochondrial Dysfunction

GBP 44.99
1

Manipulation of the Avian Genome

Manipulation of the Avian Genome

Many genes have been cloned from chicken cells and during the next decade numerous laboratories will be concentrating their resources in developing ways of using these tools. Manipulation of the Avian Genome contains the most recent information from leading research laboratories in the areas of developmental and molecular genetics of the chicken. This information was presented at the Keystone Symposium held at Lake Tahoe in March 1991. The book discusses potential applications of emerging technology in basic science and poultry production. Various techniques for altering genomic DNA such as microinjection retroviral vectors and lipofection are covered. Genome evaluation using DNA fingerprinting and conventional breeding techniques are presented.

GBP 59.99
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Genomes 5

Genomes 5

Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with previous Genomes editions techniques come first then genome anatomies followed by genome function and finally genome evolution. The genomes of all types of organism are covered: viruses bacteria fungi plants and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised to include new developments in long-read DNA sequencing. Coverage of genome annotation emphasizes genome-wide RNA mapping with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the chapters that describe the three main types of genomes: eukaryotic prokaryotic (including eukaryotic organelles) and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic concentrating on the genome-wide implications of DNA packaging epigenome modifications DNA-binding proteins non-coding RNAs regulatory genome sequences and protein-protein interactions. Also included are examples of the applications of metabolomics and systems biology. The final chapter is on genome evolution including the evolution of the epigenome using genomics to study human evolution and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Genomes 5 is the ideal text for upper-level courses focused on genomes and genomics. Key Features A highly accessible and well-structured book with chapters organized into four parts to aid navigation Superb artwork illustrates the key concepts and mechanisms Each chapter has a set of short-answer questions and in-depth problems to test the reader’s understanding of the material Thoroughly up to date with references to the latest research from the 2020s

GBP 64.99
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How to Raise a Puppy A Dog-centric Approach

How to Raise a Puppy A Dog-centric Approach

How to Raise a Puppy moves away from the traditional approach to raising puppies focused on obedience and control and instead takes an holistic dog-centred approach. Drawing on research into how dogs naturally rear their young and how dogs have evolved to behave and spend their time it supports a new way of sharing our lives with our dogs. It also offers advice on dealing with some of the common challenges people experience with puppies and tips for managing adolescence. A much-needed resource for dog trainers veterinarians and behaviourists to recommend to clients this conveys a powerful message to help overcome all too common issues so many people have with their puppies. Packed with practical advice it offers an overdue puppy perspective with respect for a dog as a sentient being at its core. | How to Raise a Puppy A Dog-centric Approach

GBP 12.99
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Nutrigenomics and Nutraceuticals Clinical Relevance and Disease Prevention

Nutrigenomics and Nutraceuticals Clinical Relevance and Disease Prevention

Genomics and related areas of research have contributed greatly to the understanding of the cellular and molecular mechanisms underlying diet–disease relationships. In the past decade the evidence has become stronger for a direct link between genome/epigenome damage and increased risk for adverse health outcomes. It is now exceedingly clear that micronutrients are critical as cofactors for many cellular functions including DNA repair enzymes methylation of CpG sequences DNA oxidation and/or uracil incorporation into DNA. Nutrigenomics and Nutraceuticals: Clinical Relevance and Disease Prevention brings new perspectives on disease prevention strategy based on the genomic knowledge and nutraceuticals of an individual and the diet he or she receives. This book discusses the integration and application of genetic and genomics technology into nutrition research and paves the way for the development of nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. In this book the editors bring together a wide spectrum of nutritional scientists worldwide to contribute to the growing knowledge in the field of nutrigenomics and nutraceuticals. | Nutrigenomics and Nutraceuticals Clinical Relevance and Disease Prevention

GBP 175.00
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