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Sequential Analysis Hypothesis Testing and Changepoint Detection

Sequential Analysis Hypothesis Testing and Changepoint Detection

Sequential Analysis: Hypothesis Testing and Changepoint Detection systematically develops the theory of sequential hypothesis testing and quickest changepoint detection. It also describes important applications in which theoretical results can be used efficiently. The book reviews recent accomplishments in hypothesis testing and changepoint detection both in decision-theoretic (Bayesian) and non-decision-theoretic (non-Bayesian) contexts. The authors not only emphasize traditional binary hypotheses but also substantially more difficult multiple decision problems. They address scenarios with simple hypotheses and more realistic cases of two and finitely many composite hypotheses. The book primarily focuses on practical discrete-time models with certain continuous-time models also examined when general results can be obtained very similarly in both cases. It treats both conventional i. i. d. and general non-i. i. d. stochastic models in detail including Markov hidden Markov state-space regression and autoregression models. Rigorous proofs are given for the most important results. Written by leading authorities in the field this book covers the theoretical developments and applications of sequential hypothesis testing and sequential quickest changepoint detection in a wide range of engineering and environmental domains. It explains how the theoretical aspects influence the hypothesis testing and changepoint detection problems as well as the design of algorithms. | Sequential Analysis Hypothesis Testing and Changepoint Detection

GBP 44.99
1

Statistical Testing Strategies in the Health Sciences

Statistical Testing Strategies in the Health Sciences

Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap between theoretical statistical methods and practical procedures applied to the planning and analysis of health-related experiments. The book is organized primarily based on the type of questions to be answered by inference procedures or according to the general type of mathematical derivation. It establishes the theoretical framework for each method with a substantial amount of chapter notes included for additional reference. It then focuses on the practical application for each concept providing real-world examples that can be easily implemented using corresponding statistical software code in R and SAS. The book also explains the basic elements and methods for constructing correct and powerful statistical decision-making processes to be adapted for complex statistical applications. With techniques spanning robust statistical methods to more computationally intensive approaches this book shows how to apply correct and efficient testing mechanisms to various problems encountered in medical and epidemiological studies including clinical trials. Theoretical statisticians medical researchers and other practitioners in epidemiology and clinical research will appreciate the book’s novel theoretical and applied results. The book is also suitable for graduate students in biostatistics epidemiology health-related sciences and areas pertaining to formal decision-making mechanisms.

GBP 44.99
1

The Weibull Distribution A Handbook

An Introduction to Nonparametric Statistics

Accelerated Life Models Modeling and Statistical Analysis

A Course in the Large Sample Theory of Statistical Inference

Handbook of Statistical Methods for Randomized Controlled Trials

Handbook of Statistical Methods for Randomized Controlled Trials

Statistical concepts provide scientific framework in experimental studies including randomized controlled trials. In order to design monitor analyze and draw conclusions scientifically from such clinical trials clinical investigators and statisticians should have a firm grasp of the requisite statistical concepts. The Handbook of Statistical Methods for Randomized Controlled Trials presents these statistical concepts in a logical sequence from beginning to end and can be used as a textbook in a course or as a reference on statistical methods for randomized controlled trials. Part I provides a brief historical background on modern randomized controlled trials and introduces statistical concepts central to planning monitoring and analysis of randomized controlled trials. Part II describes statistical methods for analysis of different types of outcomes and the associated statistical distributions used in testing the statistical hypotheses regarding the clinical questions. Part III describes some of the most used experimental designs for randomized controlled trials including the sample size estimation necessary in planning. Part IV describe statistical methods used in interim analysis for monitoring of efficacy and safety data. Part V describe important issues in statistical analyses such as multiple testing subgroup analysis competing risks and joint models for longitudinal markers and clinical outcomes. Part VI addresses selected miscellaneous topics in design and analysis including multiple assignment randomization trials analysis of safety outcomes non-inferiority trials incorporating historical data and validation of surrogate outcomes.

GBP 59.99
1

Statistical Design and Analysis of Stability Studies

Statistical Design and Analysis of Stability Studies

The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates. Pharmaceutical companies conduct stability studies to characterize the degradation of drug products and to estimate drug shelf life. Illustrating how stability studies play an important role in drug safety and quality assurance Statistical Design and Analysis of Stability Studies presents the principles and methodologies in the design and analysis of stability studies. After introducing the basic concepts of stability testing the book focuses on short-term stability studies and reviews several methods for estimating drug expiration dating periods. It then compares some commonly employed study designs and discusses both fixed and random batch statistical analyses. Following a chapter on the statistical methods for stability analysis under a linear mixed effects model the book examines stability analyses with discrete responses multiple components and frozen drug products. In addition the author provides statistical methods for dissolution testing and explores current issues and recent developments in stability studies. To ensure the safety of consumers professionals in the field must carry out stability studies to determine the reliability of drug products during their expiration period. This book provides the material necessary for you to perform stability designs and analyses in pharmaceutical research and development.

GBP 44.99
1

Statistical Inference Based on Divergence Measures

Statistical Inference Based on Divergence Measures

The idea of using functionals of Information Theory such as entropies or divergences in statistical inference is not new. However in spite of the fact that divergence statistics have become a very good alternative to the classical likelihood ratio test and the Pearson-type statistic in discrete models many statisticians remain unaware of this powerful approach. Statistical Inference Based on Divergence Measures explores classical problems of statistical inference such as estimation and hypothesis testing on the basis of measures of entropy and divergence. The first two chapters form an overview from a statistical perspective of the most important measures of entropy and divergence and study their properties. The author then examines the statistical analysis of discrete multivariate data with emphasis is on problems in contingency tables and loglinear models using phi-divergence test statistics as well as minimum phi-divergence estimators. The final chapter looks at testing in general populations presenting the interesting possibility of introducing alternative test statistics to classical ones like Wald Rao and likelihood ratio. Each chapter concludes with exercises that clarify the theoretical results and present additional results that complement the main discussions. Clear comprehensive and logically developed this book offers a unique opportunity to gain not only a new perspective on some standard statistics problems but the tools to put it into practice.

GBP 44.99
1

Project-Based R Companion to Introductory Statistics

Project-Based R Companion to Introductory Statistics

Project-Based R Companion to Introductory Statistics is envisioned as a companion to a traditional statistics or biostatistics textbook with each chapter covering traditional topics such as descriptive statistics regression and hypothesis testing. However unlike a traditional textbook each chapter will present its material using a complete step-by-step analysis of a real publicly available dataset with an emphasis on the practical skills of testing assumptions data exploration and forming conclusions. The chapters in the main body of the book include a worked example showing the R code used at each step followed by a multi-part project for students to complete. These projects which could serve as alternatives to traditional discrete homework problems will illustrate how to put the pieces together and conduct a complete start-to-finish data analysis using the R statistical software package. At the end of the book there are several projects that require the use of multiple statistical techniques that could be used as a take-home final exam or final project for a class. Key features of the text: Organized in chapters focusing on the same topics found in typical introductory statistics textbooks (descriptive statistics regression two-way tables hypothesis testing for means and proportions etc. ) so instructors can easily pair this supplementary material with course plans Includes student projects for each chapter which can be assigned as laboratory exercises or homework assignments to supplement traditional homework Features real-world datasets from scientific publications in the fields of history pop culture business medicine and forensics for students to analyze Allows students to gain experience working through a variety of statistical analyses from start to finish The book is written at the undergraduate level to be used in an introductory statistical methods course or subject-specific research methods course such as biostatistics or research methods for psychology or business analytics. Author After a 10-year career as a research biostatistician in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin-Madison Chelsea Myers teaches statistics and biostatistics at Rollins College and Valencia College in Central Florida. She has authored or co-authored more than 30 scientific papers and presentations and is the creator of the MCAT preparation website MCATMath. com.

GBP 48.99
1

A Concise Introduction to Robot Programming with ROS2

Software Engineering for Science

Software Engineering for Science

Software Engineering for Science provides an in-depth collection of peer-reviewed chapters that describe experiences with applying software engineering practices to the development of scientific software. It provides a better understanding of how software engineering is and should be practiced and which software engineering practices are effective for scientific software. The book starts with a detailed overview of the Scientific Software Lifecycle and a general overview of the scientific software development process. It highlights key issues commonly arising during scientific software development as well as solutions to these problems. The second part of the book provides examples of the use of testing in scientific software development including key issues and challenges. The chapters then describe solutions and case studies aimed at applying testing to scientific software development efforts. The final part of the book provides examples of applying software engineering techniques to scientific software including not only computational modeling but also software for data management and analysis. The authors describe their experiences and lessons learned from developing complex scientific software in different domains. About the EditorsJeffrey Carver is an Associate Professor in the Department of Computer Science at the University of Alabama. He is one of the primary organizers of the workshop series on Software Engineering for Science (http://www. SE4Science. org/workshops). Neil P. Chue Hong is Director of the Software Sustainability Institute at the University of Edinburgh. His research interests include barriers and incentives in research software ecosystems and the role of software as a research object. George K. Thiruvathukal is Professor of Computer Science at Loyola University Chicago and Visiting Faculty at Argonne National Laboratory. His current research is focused on software metrics in open source mathematical and scientific software.

GBP 44.99
1

Data Analysis Using Hierarchical Generalized Linear Models with R

Computational Aspects of Psychometric Methods With R

Design and Analysis of Experiments and Observational Studies using R

Fundamentals of Mathematical Statistics

Statistics in Toxicology Using R

Handbook of Spatial Epidemiology

Handbook of Spatial Epidemiology

Handbook of Spatial Epidemiology explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists geographers and statisticians share interdisciplinary viewpoints on analyzing spatial data and space–time variations in disease incidences. These analyses can provide important information that leads to better decision making in public health. The first part of the book addresses general issues related to epidemiology GIS environmental studies clustering and ecological analysis. The second part presents basic statistical methods used in spatial epidemiology including fundamental likelihood principles Bayesian methods and testing and nonparametric approaches. With a focus on special methods the third part describes geostatistical models splines quantile regression focused clustering mixtures multivariate methods and much more. The final part examines special problems and application areas such as residential history analysis segregation health services research health surveys infectious disease veterinary topics and health surveillance and clustering. Spatial epidemiology also known as disease mapping studies the geographical or spatial distribution of health outcomes. This handbook offers a wide-ranging overview of state-of-the-art approaches to determine the relationships between health and various risk factors empowering researchers and policy makers to tackle public health problems.

GBP 66.99
1

Basic Statistics and Pharmaceutical Statistical Applications

Solvency Models Assessment and Regulation

Nonlinear Time Series Semiparametric and Nonparametric Methods

Nonlinear Time Series Semiparametric and Nonparametric Methods

Useful in the theoretical and empirical analysis of nonlinear time series data semiparametric methods have received extensive attention in the economics and statistics communities over the past twenty years. Recent studies show that semiparametric methods and models may be applied to solve dimensionality reduction problems arising from using fully nonparametric models and methods. Answering the call for an up-to-date overview of the latest developments in the field Nonlinear Time Series: Semiparametric and Nonparametric Methods focuses on various semiparametric methods in model estimation specification testing and selection of time series data. After a brief introduction the book examines semiparametric estimation and specification methods and then applies these approaches to a class of nonlinear continuous-time models with real-world data. It also assesses some newly proposed semiparametric estimation procedures for time series data with long-range dependence. Even though the book only deals with climatological and financial data the estimation and specifications methods discussed can be applied to models with real-world data in many disciplines. This resource covers key methods in time series analysis and provides the necessary theoretical details. The latest applied finance and financial econometrics results and applications presented in the book enable researchers and graduate students to keep abreast of developments in the field. | Nonlinear Time Series Semiparametric and Nonparametric Methods

GBP 59.99
1

Translational Medicine Strategies and Statistical Methods

Translational Medicine Strategies and Statistical Methods

Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result translational medicine (TM) is becoming increasingly important in the healthcare industry – a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery through pre-clinical testing early clinical trials and late confirmatory studies that lead to regulatory approval of drug release to patients. Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patient’s bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research. Documents Alternative Research Approaches for Faster and More Accurate Data Judgment CallsElaborating on how to introduce TM into clinical studies this authoritative work presents a keen approach to building executing and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts. This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists research executives clinicians and biostatisticians looking to expedite successful implementation of this important process. | Translational Medicine Strategies and Statistical Methods

GBP 59.99
1

Machine Learning for Factor Investing: R Version

Machine Learning for Factor Investing: R Version

Machine learning (ML) is progressively reshaping the fields of quantitative finance and algorithmic trading. ML tools are increasingly adopted by hedge funds and asset managers notably for alpha signal generation and stocks selection. The technicality of the subject can make it hard for non-specialists to join the bandwagon as the jargon and coding requirements may seem out of reach. Machine Learning for Factor Investing: R Version bridges this gap. It provides a comprehensive tour of modern ML-based investment strategies that rely on firm characteristics. The book covers a wide array of subjects which range from economic rationales to rigorous portfolio back-testing and encompass both data processing and model interpretability. Common supervised learning algorithms such as tree models and neural networks are explained in the context of style investing and the reader can also dig into more complex techniques like autoencoder asset returns Bayesian additive trees and causal models. All topics are illustrated with self-contained R code samples and snippets that are applied to a large public dataset that contains over 90 predictors. The material along with the content of the book is available online so that readers can reproduce and enhance the examples at their convenience. If you have even a basic knowledge of quantitative finance this combination of theoretical concepts and practical illustrations will help you learn quickly and deepen your financial and technical expertise.

GBP 66.99
1

Probability Statistics and Data A Fresh Approach Using R

Probability Statistics and Data A Fresh Approach Using R

This book is a fresh approach to a calculus based first course in probability and statistics using R throughout to give a central role to data and simulation. The book introduces probability with Monte Carlo simulation as an essential tool. Simulation makes challenging probability questions quickly accessible and easily understandable. Mathematical approaches are included using calculus when appropriate but are always connected to experimental computations. Using R and simulation gives a nuanced understanding of statistical inference. The impact of departure from assumptions in statistical tests is emphasized quantified using simulations and demonstrated with real data. The book compares parametric and non-parametric methods through simulation allowing for a thorough investigation of testing error and power. The text builds R skills from the outset allowing modern methods of resampling and cross validation to be introduced along with traditional statistical techniques. Fifty-two data sets are included in the complementary R package fosdata. Most of these data sets are from recently published papers so that you are working with current real data which is often large and messy. Two central chapters use powerful tidyverse tools (dplyr ggplot2 tidyr stringr) to wrangle data and produce meaningful visualizations. Preliminary versions of the book have been used for five semesters at Saint Louis University and the majority of the more than 400 exercises have been classroom tested. | Probability Statistics and Data A Fresh Approach Using R

GBP 82.99
1

Machine Learning for Factor Investing Python Version

Machine Learning for Factor Investing Python Version

Machine learning (ML) is progressively reshaping the fields of quantitative finance and algorithmic trading. ML tools are increasingly adopted by hedge funds and asset managers notably for alpha signal generation and stocks selection. The technicality of the subject can make it hard for non-specialists to join the bandwagon as the jargon and coding requirements may seem out-of-reach. Machine learning for factor investing: Python version bridges this gap. It provides a comprehensive tour of modern ML-based investment strategies that rely on firm characteristics. The book covers a wide array of subjects which range from economic rationales to rigorous portfolio back-testing and encompass both data processing and model interpretability. Common supervised learning algorithms such as tree models and neural networks are explained in the context of style investing and the reader can also dig into more complex techniques like autoencoder asset returns Bayesian additive trees and causal models. All topics are illustrated with self-contained Python code samples and snippets that are applied to a large public dataset that contains over 90 predictors. The material is available online so that readers can reproduce and enhance the examples at their convenience. If you have even a basic knowledge of quantitative finance this combination of theoretical concepts and practical illustrations will help you learn quickly and deepen your financial and technical expertise. | Machine Learning for Factor Investing Python Version

GBP 66.99
1