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DNA Repair and Replication Mechanisms and Clinical Significance

DNA Repair and Replication Mechanisms and Clinical Significance

DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways. Key Selling Features: Chapters written by leading researchers Includes description of replication processes causes of damage and methods of repair | DNA Repair and Replication Mechanisms and Clinical Significance

GBP 77.99
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Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA RNA and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous yet still concise summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system Coronaviruses – structure genome vaccine and drug development and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology. Key Features Highlights the experimental basis of important discoveries in molecular biology Thoroughly updated with new information on gene editing tools viruses and transcription mechanisms termination and antisense Provides learning objectives for each chapter Includes a list of relevant videos from the Internet about the topics covered in the chapter | Molecular Biology Structure and Dynamics of Genomes and Proteomes

GBP 64.99
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Bacterial Genetics and Genomics

Bacterial Genetics and Genomics

Our understanding of bacterial genetics has progressed as the genomics field has advanced. Genetics and genomics complement and influence each other; they are inseparable. Under the novel insights from genetics and genomics once-believed borders in biology start to fade: biological knowledge of the bacterial world is being viewed under a new light and concepts are being redefined. Species are difficult to delimit and relationships within and between groups of bacteria – the whole concept of a tree of life – is hotly debated when dealing with bacteria. The DNA within bacterial cells contains a variety of features and signals that influence the diversity of the microbial world. This text assumes readers have some knowledge of genetics and microbiology but acknowledges that it can be varied. Therefore the book includes all of the information that readers need to know in order to understand the more advanced material in the book. | Bacterial Genetics and Genomics

GBP 66.99
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Human Molecular Genetics

Human Molecular Genetics

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics genomics and cell biology. Maintaining the features that have made previous editions so popular this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized coverage of newer DNA sequencing technologies has been expanded and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS functional genomics stem cells and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation. Key features: Fully integrated approach to the molecular aspects of human genetics genomics and cell biology Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms Summary boxes at the end of each chapter provide clear learning points Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study Reorganized into five sections for improved access to related topics Also new to this edition – brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics A proven and popular textbook for upper-level undergraduates and graduate students the new edition of Human Molecular Genetics remains the ‘go-to’ book for those studying human molecular genetics or genomics courses around the world.

GBP 74.99
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Plant Ecology and Conservation

Plant Ecology and Conservation

Plant Ecology & Conservation is an introduction to the world of plant ecology. It includes the main areas of current research including ideas about plant populations nutrition and plant community ecology and has a particular emphasis on the interactions of plants with animals fungi and microorganisms whose important is being increasingly demonstrated. With the world’s environmental problems having such a high profile the book focusses on the human impact on the world’s plant species. Conservation of the terrestrial world starts with plants as they form the basis of all ecosystems on land. We can only understand how best to conserve the world’s biodiversity with an understanding of the central role of plant ecology. This theme runs throughout with numerous examples of the disruption of ecosystems by human activity emphasising the connection between plant ecology and conservation. Key Features: Boxes present case studies important statistics and interesting asides Full-colour photos depict key species and habitats and superb line drawings illustrate many concepts Important data are presented in Tables and Figures throughout Each chapter has Key Concepts and review questions to test a reader’s grasp of the content Key References and Further Reading are given for each chapter to point the reader towards the most important and influential literature Jargon is kept to a minimum and a full Glossary of all technical terms is presented The book is aimed primarily at undergraduate and graduate students in any aspect of ecology or plant science. It should also appeal to anyone interested in how plants function and are concerned about what is needed for the conservation of the world’s ecosystems.

GBP 44.99
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