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Genetic Engineering Volume 1: Principles Mechanism and Expression

Genetic Engineering Volume 1: Principles Mechanism and Expression

This new 2-volume set explores new research and perspectives in genetic engineering which enables the precise control of the genetic composition and gene expression of organism. This powerful technology can be used for environmental sustainability food and nutritional security medicinal advancement and more. Genetic Engineering aims to provide a deep understanding of the many aspects of this emerging technology and its diverse applications. Genetic Engineering Volume 1: Principles Mechanism and Expression covers genetic engineering concepts molecular tools and technologies utilized in the manipulation amplification and introgression of DNA. The volume explains the concepts of genetic engineering enzymes of genetic engineering and tools used in genetic engineering. It provides an introduction of recombinant DNA into host cells and discusses the linking of desired gene with DNA vector/gene cloning vector polymerase chain reactions the concept and nature of genes blotting techniques chromosome jumping electrophoresis genetically engineered microorganisms and molecular markers and their applications. Genetic Engineering Volume 2: Applications Bioethics and Biosafety expresses the various appreciation and challenges of genetic engineering and issues related to bioethics and biosafety. Chapters cover the legal issues of genetic engineering including intellectual property rights (IPR) and protection (IPP) and the patenting of living organisms copyrights trade secrets and trademarks. The volume considers the safety and benefits of genetic engineering in human welfare such as in genetically engineered Bt and Bt cotton along with the biohazards of recombinant DNA technology. Chapters explain genetically modified organisms and microorganisms genetic engineering of horticultural crops genetic engineering in the agricultural sciences and more. This 2-volume book will be a valuable asset to upper-level students in cell biology as well as to faculty and researchers involved in genetics molecular genetics biochemistry biotechnology botany zoology and agriculture sciences.

GBP 131.00
1

Diagnostics and Gene Therapy for Human Genetic Disorders

Diagnostics and Gene Therapy for Human Genetic Disorders

Diagnostics and Gene Therapy for Human Genetic Disorders provides an integrative and comprehensive source of information blending classical human genetics with the human genome. It provides a multidisciplinary overview of Mendelian inheritance and multifactorial inheritance genetic variations polymorphisms chromosomal multifactorial and mitochondrial disorders. PCR electrophoresis cytogenetics prenatal and HPLC based techniques applied for diagnosing genetic disorders are discussed with applications. Symptoms etiology diagnosis treatment of 14 major and 5 minor genetic disorders are discussed in detail. Methods employed for the preparation of kits for the diagnosis of diseases are provided. The role of gene therapy in the amelioration of genetic disorders and the methodology employed are discussed. The success of gene therapy in controlling various disorders such as immune system disorders neurodegenerative disorders cardiovascular disorders eye diseases and cancer has been described along with type studies. Features: A blend of classical human genetics with molecular and genome-based applications Techniques applied for the diagnosis of genetic disorders Diagnostics of 19 genetic disorders including symptoms etiology diagnosis and treatment Role of gene therapy in the amelioration of disorders Type studies describing the role of diagnostics in conserving the human health This book attempts to connect all the information about classical and modern human genetics genetic disorders and gene therapy to all types of diseases in one place. This work provides a comprehensive source of information that can serve as a reference book for scientific investigations and as a textbook for the graduate students.

GBP 110.00
1

Proceedings of the First International Conference on Genetic Algorithms and their Applications

Genetic Theory of Reality

CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials: Theoretical Foundations explores the mathematical foundations and emerging applications of this testing process which is based on elastic wave propagation in isotropic and anisotropic solids. In covering ultrasonic nondestructive testing methods the book emphasizes the engineering point of view yet it relies on the physics and mathematics aspects involved in elastic wave propagation theory. As a result this resource becomes a missing link in the literature by combining coverage of the theoretical aspects of testing and providing intuitive assessments of numerous standard problems to illustrate fundamental assertions. Content includes a brief description of the theory of acoustic and electromagnetic fields to underline the similarities and differences as compared to elastodynamics. It also covers vector algebra and analysis elastic plane and Rayleigh surface waves and ultrasonic beams as well as transducer radiation inverse scattering and ultrasonic nondestructive imaging. Includes numerical computations to explain wave propagation phenomena and compare results of analytical formulations Although ultrasonic nondestructive testing can often be roughly understood in terms of plane waves and beams this book addresses the key issues of transducer radiation and defect scattering and imaging respectively. The authors physically formulate point source synthesis and in mathematical terms they use representation integrals with Green functions always including intuitive interpretations with mathematical evaluations. Replacing cumbersome index notation with a coordinate-free version this reference offers step-by-step documentation of relevant tensorial elastodynamic cases involving isotropic and anisotropic materials. It provides all necessary mathematical tools readers require to understand the mathematical and physical basis for ultrasonic nondestructive testing. | Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

GBP 94.99
1

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook: Transients Control Principles Design and Testing presents a practical up-to-date treatment of intricate issues with induction machines (IM) required for design and testing in both rather constant- and variable-speed (with power electronics) drives. It contains ready-to-use industrial design and testing knowledge with numerous case studies to facilitate a thorough assimilation of new knowledge. Individual Chapters 1 through 14 discuss in detail the following: Three- and multiphase IM transients Single-phase source IM transients Super-high-frequency models and behavior of IM Motor specifications and design principles IM design below 100 kW and constant V1 and f1 IM design above 100 kW and constant V1 and f1 IM design principles for variable speed Optimization design Single-phase IM design Three-phase IM generators Single-phase IM generators Linear induction motors Testing of three-phase IMs Single-phase IM testing Fully revised and amply updated to add the new knowledge of the last decade this third edition includes special sections on Multiphase IM models for transients Doubly fed IMs models for transients Cage-rotor synchronized reluctance motors Cage-rotor PM synchronous motor Transient operation of self-excited induction generator Brushless doubly fed induction motor/generators Doubly fed induction generators with D. C. output Linear induction motor control with end effect Recent trends in IM testing with power electronics Cage-PM rotor line-start IM testing Linear induction motor (LIM) testing This up-to-date book discusses in detail the transients control principles and design and testing of various IMs for line-start and variable-speed applications in various topologies with numerous case studies. It will be of direct assistance to academia and industry in conceiving designing fabricating and testing IMs (for the future) of various industries from home appliances through robotics e-transport and renewable energy conversion. | Induction Machines Handbook Transients Control Principles Design and Testing

GBP 140.00
1

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials: Introduction and Laboratory Testing discusses the properties characterization procedures and analysis techniques of primary civil engineering materials. It presents the latest design considerations and uses of engineering materials as well as theories for fully understanding them through numerous worked mathematical examples. The book also includes important laboratory tests which are clearly described in a step-by-step manner and further illustrated by high-quality figures. Also analysis equations and their applications are presented with appropriate examples and relevant practice problems including Fundamentals of Engineering (FE) styled questions as well those found on the American Concrete Institute (ACI) Concrete Field Testing Technician - Grade I certification exam. Features: Includes numerous worked examples to illustrate the theories presented Presents Fundamentals of Engineering (FE) examination sample questions in each chapter Reviews the ACI Concrete Field Testing Technician - Grade I certification exam Utilizes the latest laboratory testing standards and practices Includes additional resources for instructors teaching related courses This book is intended for students in civil engineering construction engineering civil engineering technology construction management engineering technology and construction management programs. | Civil Engineering Materials Introduction and Laboratory Testing

GBP 99.99
1

Cone Penetration Testing 2022 Abstracts Volume

Testing of Concrete in Structures Fourth Edition

Testing and Balancing HVAC Air and Water Systems

Testing and Balancing HVAC Air and Water Systems

This thoroughly revised book will provide the reader with an understanding of the principles and practices of testing and balancing (TAB) heating ventilating and air conditioning (HVAC) air and water systems. It is for anyone interested in testing and balancing. For the novice and the experienced testing and balancing technician it is a field reference book of procedures equations and information tables. For those interested in getting into TAB or who are new to the HVAC industry it is a text for learning more about HVAC systems and testing and balancing. For the mechanical engineer building owner facility manager commissioning agency or energy manager this book can be used for teaching TAB writing more effective specifications and learning about TAB and how it interacts with system commissioning indoor air quality and energy management. It is the intent of this book to improve the communications between owners mechanical engineers designers vendors contractors TAB engineers supervisors and technicians to ensure that HVAC systems are being thoroughly tested and balanced. This book is used in test and balance self-study courses in-house training programs seminars and other training formats as preparation for TAB certification and as a text in colleges and technical schools. The sixth edition has general and specific testing and balancing procedures for constant air volume systems variable air volume systems return air and exhaust air systems positive and negative pressure conditioned spaces and fans and fan performance in Chapters 1 through 9. Chapters 10–12 cover testing and balancing fume hood systems and cleanrooms and commissioning HVAC systems. Chapters 13 and 14 provide information on water systems and centrifugal pumps including water balancing procedures using flow meters system components and temperatures and water pumps and pump performance. Chapter 15 reviews analog and digital controls. Chapters 16–20 cover terminology for fluid flow psychrometrics refrigeration¸ air distribution water distribution fans and pumps motors electrical and instrument usage and care. Chapters 21 and 22 are equations and tables. | Testing and Balancing HVAC Air and Water Systems

GBP 120.00
1

Introduction to Soil Mechanics Laboratory Testing

GBP 175.00
1

Composite Structures Design Mechanics Analysis Manufacturing and Testing

Ethical Hacking and Penetration Testing Guide

Ethical Hacking and Penetration Testing Guide

Requiring no prior hacking experience Ethical Hacking and Penetration Testing Guide supplies a complete introduction to the steps required to complete a penetration test or ethical hack from beginning to end. You will learn how to properly utilize and interpret the results of modern-day hacking tools which are required to complete a penetration test. The book covers a wide range of tools including Backtrack Linux Google reconnaissance MetaGooFil dig Nmap Nessus Metasploit Fast Track Autopwn Netcat and Hacker Defender rootkit. Supplying a simple and clean explanation of how to effectively utilize these tools it details a four-step methodology for conducting an effective penetration test or hack. Providing an accessible introduction to penetration testing and hacking the book supplies you with a fundamental understanding of offensive security. After completing the book you will be prepared to take on in-depth and advanced topics in hacking and penetration testing. The book walks you through each of the steps and tools in a structured orderly manner allowing you to understand how the output from each tool can be fully utilized in the subsequent phases of the penetration test. This process will allow you to clearly see how the various tools and phases relate to each other. An ideal resource for those who want to learn about ethical hacking but don‘t know where to start this book will help take your hacking skills to the next level. The topics described in this book comply with international standards and with what is being taught in international certifications.

GBP 170.00
1

Process Plant Piping Practical Guide to Fabrication Installation Inspection Testing and Commissioning

Process Plant Piping Practical Guide to Fabrication Installation Inspection Testing and Commissioning

This book is designed as a complete guide to manufacturing installation inspection testing and commissioning of process plant piping. It provides exhaustive coverage of the entire piping spool fabrication including receiving material inspection at site material traceability installation of spools at site inspection testing and pre-commissioning activities. In nutshell it serves as a complete guide to piping fabrication and erection. In addition typical formats for use in piping fabrication for effective implementation of QA/QC requirements inspection and test plans and typical procedures for all types of testing are included. Features: Provides an overview of development of piping documentation in process plant design with number of illustrations Gives exposure to various codes used in piping and pipelines within its jurisdiction Quick reference guide to various applicable sections of ASME B 31. 3 provided Coverage of entire construction contractors' scope of work with regard to plant piping Written with special emphasis on practical aspects of construction and final documentation of plant piping for later modifications/investigations This book is aimed at mechanical process and plant construction engineers/supervisors specifically as a guide to all novices in the above disciplines. | Process Plant Piping Practical Guide to Fabrication Installation Inspection Testing and Commissioning

GBP 130.00
1

Autonomous Driving and Advanced Driver-Assistance Systems (ADAS) Applications Development Legal Issues and Testing

Laboratory Manual for Exercise Physiology Exercise Testing and Physical Fitness

Art Conservation Mechanical Properties and Testing of Materials

Radiation Detection Systems Medical Imaging Industrial Testing and Security Applications

Radiation Detection Systems Medical Imaging Industrial Testing and Security Applications

The advances in semiconductor detectors scintillators photodetectors such as silicon photomultipliers (SiPM) and readout electronics have experienced tremendous growth in recent years in terms of basic technologies and a variety of applications. The second edition of Radiation Detection Systems presents variety of radiation detection systems giving readers a broad view of the state-of-the-art in the design of detectors front-end electronics and systems offering optimized choices of the detection tools for a particular application. The new edition has been divided into two volumes. This volume on Medical Imaging Industrial Testing and Security Applications presents specific applications of the detection systems in medical imaging industrial testing and security applications. These newely developed technologies play a vital role in the detection diagnosis and treatment of major human diseases. Featuring contributions from leading experts and pioneers in their respective fields this book: Describes new advances in development of detection systems based on CdZnTe (CZT) and CdTe detectors utilizing a direct conversion of radiation to electric signals Reports a recent progress in technologies and performance of SiPM used for reading the light from scintillators Explores exciting new application opportunities created by development of the cutting-edge detection technologies in X-ray spectroscopy computed tomography (CT) bone dosimetry and nuclear medicine (PET SPECT) Considers the future use of photon-counting detectors in clinical CT scanners providing K-edge imaging to reduce the amount of contrast agents and ultimately offering both an anatomical and a functional information Describes uses of radiation detection systems in security applications such as luggage scanning dirty bomb detection and border control With its combined coverage of new materials and innovative new system approaches as well as a succinct overview of recent developments this book is an invaluable tool for any engineer professional or student working in electronics or an associated field. Readers can refer to the other volume Sensor Materials Systems Technology and Characterization Measurements which puts emphasis on sensor materials detector structures front electronics technology and their designs and system optimization for different applications. | Radiation Detection Systems Medical Imaging Industrial Testing and Security Applications

GBP 115.00
1

Cardiovascular Disease in Companion Animals Dog Cat and Horse

Cardiovascular Disease in Companion Animals Dog Cat and Horse

*Note that the supplementary electronic material for Chapters 26-40 will be available in the Support Material tab soon* This new edition of Cardiovascular Disease in Companion Animals authored by two leading experts in the field now covers the horse as well as the dog and cat. The comprehensive superbly illustrated book has been completely revised and expanded from the original Cardiovascular Disease in Small Animal Medicine. Five key sections provide clearly written overviews of normal cardiovascular structure and function pathophysiologic derangements and their manifestations clinical cardiology testing and interpretation and extensive guidance for cardiovascular disease diagnosis and management. A broad collection of clinical images graphics tables diagrams and a Summary Drug Tables for each species enhances the book’s utility as a practical clinical resource. Up-to-date references support the focus on cardiovascular diseases and reflect important developments in veterinary cardiology and practice. A valuable companion website contains videos and additional images to enhance each chapter. Since first publication in 2007 Dr Ware’s authoritative yet user-friendly guide to cardiovascular diseases in veterinary practice has been widely praised. This book contains even more illustrations of the highest quality. Coverage also includes diagnostic considerations for various clinical problems procedures and techniques for patient evaluation and detailed management strategies for congestive heart failure arrhythmias and other complications of cardiovascular disease. This second edition is a must-have for veterinary practitioners students interns residents and others with an in-depth interest in veterinary cardiology. | Cardiovascular Disease in Companion Animals Dog Cat and Horse

GBP 170.00
1

Manual of Geotechnical Laboratory Soil Testing

Manual of Geotechnical Laboratory Soil Testing

Manual of Geotechnical Laboratory Soil Testing covers the physical index and engineering properties of soils including compaction characteristics (optimum moisture content) permeability (coefficient of hydraulic conductivity) compressibility characteristics and shear strength (cohesion intercept and angle of internal friction). Further this manual covers data collection analysis computations additional considerations sources of error precautionary measures and the presentation results along with well-defined illustrations for each of the listed tests. Each test is based on relevant standards with pertinent references broadly aimed at geotechnical design applications. FEATURES Provides fundamental coverage of elementary-level laboratory characterization of soils Describes objectives basic concepts general understanding and appreciation of the geotechnical principles for determination of physical index and engineering properties of soil materials Presents the step-by-step procedures for various tests based on relevant standards Interprets soil analytical data and illustrates empirical relationship between various soil properties Includes observation data sheet and analysis results and discussions and applications of test results This manual is aimed at undergraduates senior undergraduates and researchers in geotechnical and civil engineering. Prof. (Dr. ) Bashir Ahmed Mir is among the senior faculty of the Civil Engineering Department of the National Institute of Technology Srinagar and has more than two decades of teaching experience. Prof. Mir has published more than 100 research papers in international journals and conferences; chaired technical sessions in international conferences in India and throughout the world; and provided consultancy services to more than 150 projects of national importance to various government and private agencies.

GBP 105.00
1

Genetics and Randomness

Genetics and Randomness

Analyzes Randomness in Major Genetic Processes and Events No matter how far science advances the proportion of what is knowable to what is random will remain unchanged and attempts to ignore this critical threshold are futile at best. With the revolutionary explosion in genetic information discovery it is crucially important to recognize the underlying limitations of scientific prediction in genetics. Genetics and Randomness furthers the understanding of the role randomness plays in critical biological processes. The book also navigates the complex nature of genetic uncertainty from different points of view and at various levels of biological organization. Avoids Unnecessary Technical Details and Specific Terminology Exploring areas ranging from basic quantum mechanics and molecular genetics to modern evolutionary genetics and the philosophy of mathematics this well-organized text discusses: Spontaneity of mutations and their relation to subatomic randomness Deep links between subatomic fluctuations and long-term macroscopic changes in living organisms The multitude of random events that occur during development Segregation genetic drift and natural selection Randomness and uncertainty are not occasional and regretful deviations from the true principles upon which life is built. Genetics and Randomness illustrates the ubiquitous nature of randomness as an integral feature of all essential processes effectively embracing a probabilistic understanding of the phenomena of life.

GBP 175.00
1

Karch's Drug Abuse Handbook