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Forensic DNA Transfer

Forensic DNA Transfer

Forensic DNA Transfer provides a guide to the recognition and current understanding of DNA transfer in forensic criminal investigations. Increased improvements in technology mean that it is now routinely possible to obtain DNA profiles from non-visible deposits. How or when the DNA in question was deposited may be an issue in the context of the case especially if the donor of the DNA is not in dispute. A DNA profile alone cannot reveal when or how that DNA was deposited at a crime scene nor can it reveal the body matter from which it originated. Issues of transfer associated with activities may be debated—which the traditional discrimination purpose of DNA profiling cannot address. DNA may be everywhere and anywhere—in homes at workplaces during transport and on personal items including clothing. DNA from a person may be on an object they have never contacted or in a room they have never entered. Concepts discussed in the book include non-self DNA on hands through day-to-day activities the prevalence of background DNA in the environment and perhaps on the exhibit the persistence of any DNA transferred and that a DNA result will depend on these variables as well as recovery techniques. Since DNA may be transferred to an exhibit: (a) during the commission of a crime (b) before the crime and/or (c) after the crime through handling examination and testing this book covers various transfer pathways and sources of DNA. Documented cases of inadvertent transfer of DNA resulting in wrongful convictions or the misdirection of criminal investigations are discussed—with an emphasis on contamination mitigation throughout the entire process. Forensic DNA Transfer examines the additional complexity resulting from non-visible deposits of DNA that impact on sampling and testing regimes. The changing understanding of the composition of purported 'touch DNA' deposits from the skin including extracellular DNA transported via body secretions is described. Further the newer focus on interpreting DNA evidence—using activity level propositions and the rationale and associated issues—is also discussed.

GBP 46.99
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Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications An Interdisciplinary Perspective

Forensic DNA Applications: An Interdisciplinary Perspective Second Edition is fully updated to outline the latest advances in forensic DNA testing techniques and applications. It continues to fill the need for a reference book for people working in the field of forensic molecular biology testing and research as well as individuals investigating and adjudicating cases involving DNA evidence whether they be civil or criminal cases. DNA techniques have greatly impacted obvious traditional forensic areas but such advances have also positively affected myriad new areas of research and inquiry. It is possible today to think about solving forensic problems that were simply unheard of even a few years ago. As such the book pulls all relevant research and applied science together into a detailed and comprehensive collection. Part I begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples mitochondrial DNA testing Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs) and X SNP and STR testing. It also explores low copy number DNA typing mixtures and quality assurance and control. Part II moves on to cover the various uses and applications of analyzing collected physical evidence victim identification in mass disasters analyzing animal DNA forensic botany and other unique applications. Part III is dedicated to the latest advances and developments in human molecular biology and Part IV looks at policies and laws and ethics governing DNA evidence and its utilization in various cases and the courts. Forensic DNA Applications Second Edition covers cutting-edge research and advancements in the field and is the most up-to-date reference available. Edited and contributed to by the world's foremost leaders in the field it is a must-have reference for established professionals and an essential resource to legal professionals—lawyers and judges dealing with civil and criminal cases involving DNA technology—as well as students entering the fields of genetics and forensic DNA analysis. | Forensic DNA Applications An Interdisciplinary Perspective

GBP 56.99
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DNA Nanoscience From Prebiotic Origins to Emerging Nanotechnology

Artificial DNA Methods and Applications

Artificial DNA Methods and Applications

Combining elements of biochemistry molecular biology and immunology artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis hybridization amplification protein engineering anti-sense technology DNA vaccines protein vaccines recombinant antibodies screening for genetic and pathogenic diseases development of materials with new biochemical and structural properties and many more. Artificial DNA: Methods and Applications introduces the concept of artificial DNA that has been rationally designed and explains how it may be exploited in order to develop products that will achieve your intended purpose. The first part of the book covers methods of oligonucleotide synthesis and direct applications of synthetic DNA. The second part describes methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. The authors also discuss the different trends and future developments within each application area . With state-of-the art research the contributing authors describe how to engineer proteins using rational and semi-rational design to exhibit the desired traits and detail the various amplification reactions and hybridization techniques for modeling evolution and for use in basic research. The only text devoted to this subject Artificial DNA offers a comprehensive review that allows you to understand the strategy design and applications of synthetic oligonucleotides. | Artificial DNA Methods and Applications

GBP 59.99
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Forensic DNA Analysis Current Practices and Emerging Technologies

Forensic DNA Analysis Current Practices and Emerging Technologies

The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing forensic casework family lineage studies identification of human remains and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize document collect and store it. The remaining chapters examine:The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remainsStudies carried out on the use of both messenger RNA and small (micro) RNA profilingReal-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotypingCapillary electrophoresis (CE) as a tool for forensic DNA analysisNext-generation short tandem repeat (STR) genotyping kits for forensic applications the biological nature of STR loci and Y-chromosome STRs (Y-STRs)Mitochondrial DNA (mtDNA) sequence analysisSingle nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in typing highly degraded DNADeep-sequencing technologiesThe current state of integrated systems in forensic DNA analysis The book concludes by discussing various aspects of sample-processing training and the entities that provide such training programs. This volume is an essential resource for students researchers teaching faculties and other professionals interested in human identification/forensic DNA analysis. | Forensic DNA Analysis Current Practices and Emerging Technologies

GBP 77.99
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Introduction to Forensic DNA Evidence for Criminal Justice Professionals

Introduction to Forensic DNA Evidence for Criminal Justice Professionals

The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting yet for those with limited scientific knowledge understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed for nonscientific readers who need to learn how to effectively use forensic DNA in criminal cases. Written by a forensic scientist world renowned for her expertise in clothing examination the book provides a balanced perspective on the weight of DNA evidence. Going beyond a simple explanation of the methodology it arms attorneys and other criminal justice professionals with knowledge of the strengths and limitations of the evidence including the danger in relying on DNA statistical probabilities in the determination of guilt. The book covers the most common DNA methods used in criminal trials today nuclear DNA short tandem repeat (STR) techniques mitochondrial DNA and Y-STR profiling. It helps prosecutors know when to emphasize DNA evidence or proceed with trial in the absence of such evidence. It assists defense lawyers in knowing when to challenge DNA evidence and perhaps employ an independent expert when to focus elsewhere or when to secure the advantage of an early guilty plea. By imparting practical and theoretical knowledge in an accessible manner the book demystifies the topic to help both sides of the adversarial system understand where DNA evidence fits within the context of the case.

GBP 180.00
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DNA Repair and Replication Mechanisms and Clinical Significance

Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures how to assign a likelihood ratio and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods the polymerase chain reaction (PCR) capillary electrophoresis (CE) likelihood ratios (LRs) and their interpretation and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES:• The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods heretofore unpublished previously provide a means to innovate deconvoluting a mixed DNA profile assign an LR and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i. e. “It’s not me it was my brother”) and discusses strategies for the validation of probabilistic genotyping softwareForensic DNA Profiling fills the void for labs unfamiliar with LRs and moving to probabilistic solutions and for labs already familiar with LRs but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians students and legal professionals seeking to understand and apply the techniques covered. | Forensic DNA Profiling A Practical Guide to Assigning Likelihood Ratios

GBP 44.99
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Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

A powerful tool in the identification of individuals DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories Forensic Analysis of Biological Evidence: A Laboratory Guide for Serological and DNA Typing introduces readers to the science of serological analysis and DNA typing methods and provides a thorough background of the molecular techniques used to determine an individual‘s identity or parental lineage. Originally published as Forensic DNA Analysis: A Laboratory Manual this revised work offers updated exercises and protocols for all kinds of DNA and serological analyses with delineated objectives step-by-step procedures and required laboratory supplies. Each exercise in this manual: Provides an overview of forensic DNA analysis Explains the sources or types of biological material used in a particular DNA analysis Supplies the background principles and practical methodology for specific serological analysis and DNA typing techniques Simulates human forensic testing and can also be used to simulate a wide range of applications for genetic analysis The book contains an extensive glossary to make readers familiar with terminology used in the forensic analysis of biological evidence as well as basic terms used in molecular biology. Those who master the material in this volume will understand the methodology of the investigation in DNA typing develop an understanding of the scientific principles involved in serology and DNA analysis and succeed in analyzing and interpreting the data generated in each exercise with clarity and confidence. | Forensic Analysis of Biological Evidence A Laboratory Guide for Serological and DNA Typing

GBP 180.00
1

DNA Methylation Microarrays Experimental Design and Statistical Analysis

Dogs in the North Stories of Cooperation and Co-Domestication

Police and Military Dogs Criminal Detection Forensic Evidence and Judicial Admissibility

Treating Chronically Traumatized Children The Sleeping Dogs Method

Treating Chronically Traumatized Children The Sleeping Dogs Method

When children refuse or seem unable to talk about their traumatic memories it might be tempting to ‘let sleeping dogs lie’. However if left untreated the memories of childhood abuse and neglect can have a devastating effect on the development of children and young people. How can these children be motivated and engage in trauma-focused therapy? Treating Chronically Traumatized Children: The Sleeping Dogs Method describes a structured method to overcome resistance and enable children to wake these sleeping dogs safely so these children heal from their trauma. The ‘Sleeping Dogs method’ is a comprehensive approach to treating chronically traumatized children first preparing the child to such an extent that he or she can engage in therapy to process traumatic memories then by the trauma processing and integration phase. Collaboration with the child’s network the child’s biological family including the abuser-parent and child protection services are key elements of the 'Sleeping Dogs method'. The underlying theory about the consequences of traumatization such as disturbed attachment and dissociation is described in a comprehensive easy-to-read manner illustrated with case studies and is accompanied by downloadable worksheets. This new edition has been updated to include the clinical experience in working with this method and the most recent literature and research as well as entirely new chapters that apply the ‘Sleeping Dogs method’ to the experiences of children in foster care and residential care and those with an intellectual disability. Treating Chronically Traumatized Children will have a wide appeal including psychologists psychiatrists psychotherapists counsellors family therapists social workers child protection frontline foster care and youth workers inpatient and residential staff and (foster or adoptive) parents. | Treating Chronically Traumatized Children The Sleeping Dogs Method

GBP 38.99
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Dogs in Schools Pedagogy and Practice for Happy Healthy and Humane Interventions

Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R

Comprehensive Aphasia Test

Comprehensive Aphasia Test

The Comprehensive Aphasia Test (CAT) is a test for use with people who have acquired aphasia that can be completed over one or two assessment sessions. The test includes a user manual a cognitive screen and language battery and a scoring booklet which are all unchanged since the previous edition and - new to this release - a concise Aphasia Impact Questionnaire which replaces the Disability Questionnaire. The cognitive section assesses people's abilities across a range of task that can affect rehabilitation. Forming the main body of the test the language battery provides a profile of performance across all modalities of language production and comprehension. The Aphasia Impact Questionnaire is a pictorial Patient Reported Outcome Measure which produces both qualitative and quantitative information. It was co-produced with people with aphasia. It supports the person with aphasia to give a subjective rating of how language difficulties identified in the Language Battery affect their daily life enabling first steps towards goal setting. By capturing this information the CAT helps the therapist track changes over the course of recovery and provides a guide to likely outcomes on the basis of an early assessment. The first two sections of the CAT are supported by normative data on people both with and without aphasia and extensive data on reliability and clinical validity. The CAT allows users to: Identify underlying impairments Find where to focus assessments using PALPA and other batteries Ascertain the practical psychological and social impact of aphasia from the perceptive of the person with aphasia Create a profile of strengths and weaknesses to guide therapy. Structured around fully up-to-date models of language assessment from cognitive neuropsychology to patient reported outcome measures test is an indispensable resource for speech and language therapists and researchers. It provides as much information about people's language ability as possible in a relatively brief test designed to be completed in 90-120 minutes. Additional scoring booklets can be ordered in packs of 10 at https://www. routledge. com/Comprehensive-Aphasia-Test-Scoring-Book-pack-of-10/Swinburn-Porter-Howard/p/book/ 9781032128177

GBP 250.00
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The Turing Test Argument

Rotating Machinery Research and Development Test Rigs

Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs From Science to Scene

Death Decomposition and Detector Dogs: From Science to Scene Second Edition is designed to help canine handlers detectives death investigators crime scene personnel (including forensic laboratory personnel technicians and supervisors) and attorneys understand the science involved when utilizing human remains detector (HRD) canines as a locating tool. The book covers the basic anatomy and physiology of canine olfaction and the unique characteristics of their scenting ability that allows dogs to be trained to locate distinct odors. Using concise and clear explanations and photographs the book reviews the science of forensic taphonomy. Factors that may affect the decomposition process are highlighted along with what the potential outcomes that may be encountered. The book examines how the odor of human remains is generated through various stages of decomposition and the manner in which environmental conditions in both land and water settings may affect that odor. Different types of background information that may help in determining possible search locations for missing individuals are included as well as assist the HRD canine handler in developing search plans are covered. Different tools and technologies that may be used in addition to an HRD canine team are included to help readers understand that are many ways to address searching for a decedent. Several case reports involving decedents found in both land and water settings in addition to different weather conditions are included to help the reader understand how the environment may have affected the condition of the decedent. This edition includes more case reports explaining how environmental factors were considered in HRD canine deployments in both land and water settings. Understanding which variables—and how such variables—can affect the state and condition of human remains as well as dispersion of odor from human remains will help canine handlers utilize their HRD canine more effectively as a locating tool. Death Decomposition and Detector Dogs Second Edition will help HRD canine handlers and other law enforcement personnel be better prepared to meet the challenges of their jobs before during and after searches for the missing. | Death Decomposition and Detector Dogs From Science to Scene

GBP 42.99
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Practical Psychometrics A Guide for Test Users

Psoralen Dna Photobiology Volume I

Secure and Resilient Software Requirements Test Cases and Testing Methods

Secure and Resilient Software Requirements Test Cases and Testing Methods

Secure and Resilient Software: Requirements Test Cases and Testing Methods provides a comprehensive set of requirements for secure and resilient software development and operation. It supplies documented test cases for those requirements as well as best practices for testing nonfunctional requirements for improved information assurance. This resource-rich book includes:Pre-developed nonfunctional requirements that can be reused for any software development project Documented test cases that go along with the requirements and can be used to develop a Test Plan for the softwareTesting methods that can be applied to the test cases provided Downloadable resources with all security requirements and test cases as well as MS Word versions of the checklists requirements and test cases covered in the bookOffering ground-level already-developed software nonfunctional requirements and corresponding test cases and methods this book will help to ensure that your software meets its nonfunctional requirements for security and resilience. The accompanying downloadable resources filled with helpful checklists and reusable documentation provides you with the tools needed to integrate security into the requirements analysis design and testing phases of your software development lifecycle. Some Praise for the Book:This book pulls together the state of the art in thinking about this important issue in a holistic way with several examples. It takes you through the entire lifecycle from conception to implementation . . —Doug Cavit Chief Security Strategist Microsoft Corporation. provides the reader with the tools necessary to jump-start and mature security within the software development lifecycle (SDLC). —Jeff Weekes Sr. Security Architect at Terra Verde Services. full of useful insights and practical advice from two au | Secure and Resilient Software Requirements Test Cases and Testing Methods

GBP 56.99
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