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Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - Super King Size - Galvin and Galloway

Bath Grooming Table for Dogs Cats Pets Adjustable 2 Loops - Style and Chic

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook Transients Control Principles Design and Testing

Induction Machines Handbook: Transients Control Principles Design and Testing presents a practical up-to-date treatment of intricate issues with induction machines (IM) required for design and testing in both rather constant- and variable-speed (with power electronics) drives. It contains ready-to-use industrial design and testing knowledge with numerous case studies to facilitate a thorough assimilation of new knowledge. Individual Chapters 1 through 14 discuss in detail the following: Three- and multiphase IM transients Single-phase source IM transients Super-high-frequency models and behavior of IM Motor specifications and design principles IM design below 100 kW and constant V1 and f1 IM design above 100 kW and constant V1 and f1 IM design principles for variable speed Optimization design Single-phase IM design Three-phase IM generators Single-phase IM generators Linear induction motors Testing of three-phase IMs Single-phase IM testing Fully revised and amply updated to add the new knowledge of the last decade this third edition includes special sections on Multiphase IM models for transients Doubly fed IMs models for transients Cage-rotor synchronized reluctance motors Cage-rotor PM synchronous motor Transient operation of self-excited induction generator Brushless doubly fed induction motor/generators Doubly fed induction generators with D. C. output Linear induction motor control with end effect Recent trends in IM testing with power electronics Cage-PM rotor line-start IM testing Linear induction motor (LIM) testing This up-to-date book discusses in detail the transients control principles and design and testing of various IMs for line-start and variable-speed applications in various topologies with numerous case studies. It will be of direct assistance to academia and industry in conceiving designing fabricating and testing IMs (for the future) of various industries from home appliances through robotics e-transport and renewable energy conversion. | Induction Machines Handbook Transients Control Principles Design and Testing

GBP 140.00
1

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials Introduction and Laboratory Testing

Civil Engineering Materials: Introduction and Laboratory Testing discusses the properties characterization procedures and analysis techniques of primary civil engineering materials. It presents the latest design considerations and uses of engineering materials as well as theories for fully understanding them through numerous worked mathematical examples. The book also includes important laboratory tests which are clearly described in a step-by-step manner and further illustrated by high-quality figures. Also analysis equations and their applications are presented with appropriate examples and relevant practice problems including Fundamentals of Engineering (FE) styled questions as well those found on the American Concrete Institute (ACI) Concrete Field Testing Technician - Grade I certification exam. Features: Includes numerous worked examples to illustrate the theories presented Presents Fundamentals of Engineering (FE) examination sample questions in each chapter Reviews the ACI Concrete Field Testing Technician - Grade I certification exam Utilizes the latest laboratory testing standards and practices Includes additional resources for instructors teaching related courses This book is intended for students in civil engineering construction engineering civil engineering technology construction management engineering technology and construction management programs. | Civil Engineering Materials Introduction and Laboratory Testing

GBP 99.99
1