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Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Fully up-to-date with the relevant parts of the 17th Edition IET Wiring Regulations: Amendment 3 and the 2012 Code of Practice Provides all the required information on portable appliance testing in a user-friendly manner Expert advice from an engineering training consultant supported with colour diagrams examples and tables The Electricity at Work Regulations 1989 requires any electrical system to be constructed maintained and used in such a manner as to prevent danger. This means that inspection and testing of systems including portable appliances is needed in order to determine if maintenance is required. This book explains in clear language what needs to be done and includes expert advice on legislation as well as actual testing. The book contains an appendix providing the electrical fundamentals needed by non-specialists and also has sample questions (with answers) for the CandG 2377 exam. It is also an ideal revision guide for the non-specialist such as maintenance staff and caretakers who carry out these tasks part-time alongside their many other duties. | PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

GBP 175.00
1

Martindale Electric Thermokitlgn Legionella Testing Thermometry Kit

Martindale Electric Thermokitlgn Legionella Testing Thermometry Kit

Designed for monitoring water temperatures and ensuring compliance with HSE regulations, the Legionella thermometry kit from Martindale Electric is an essential tool for preventing the growth of Legionella and similar bacteria. It helps maintain a safe water supply and ensures site safety. Features and Benefits Switches effortlessly between Celsius and Fahrenheit for added user convenience Equipped with a clear LCD display for easy readability Delivers an impressive 200 hours of battery life using 4x AAA batteries Auto power-off function conserves battery life effectively Contents 1x digital thermometer 1x penetration probe 1x surface probe 1x bead type thermocouple 1x hard carry case Standards BS EN 61010-1 50V BS EN 61326-1

GBP 169.99
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway

<p>Experience ultimate comfort and allergy protection with the Ever range from Home Done. Our Simply Sleep Anti Allergy Microfibre Duvet is perfect for those with allergies, offering a luxurious feel 'Just like Down' with premium filling for warmth and comfort. The duvet is treated to be anti-allergy, featuring a 233 thread count 100% cotton percale piped case for pure luxury. Its carefully constructed baffle box stitching keeps the luxury filling evenly spaced, preventing cold patches and lumpy areas while allowing for proper aeration. Available in 10.5 Tog and four sizes: Single, Double, King, and Super King, in a classic white color.</p>

GBP 113.19
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - Single Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - Single Size - Galvin and Galloway

<p>Experience ultimate comfort and allergy protection with the Ever range from Home Done. Our Simply Sleep Anti Allergy Microfibre Duvet is perfect for those with allergies, offering a luxurious feel 'Just like Down' with premium filling for warmth and comfort. The duvet is treated to be anti-allergy, featuring a 233 thread count 100% cotton percale piped case for pure luxury. Its carefully constructed baffle box stitching keeps the luxury filling evenly spaced, preventing cold patches and lumpy areas while allowing for proper aeration. Available in 10.5 Tog and four sizes: Single, Double, King, and Super King, in a classic white color.</p>

GBP 88.89
1

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

Ultrasonic Nondestructive Testing of Materials: Theoretical Foundations explores the mathematical foundations and emerging applications of this testing process which is based on elastic wave propagation in isotropic and anisotropic solids. In covering ultrasonic nondestructive testing methods the book emphasizes the engineering point of view yet it relies on the physics and mathematics aspects involved in elastic wave propagation theory. As a result this resource becomes a missing link in the literature by combining coverage of the theoretical aspects of testing and providing intuitive assessments of numerous standard problems to illustrate fundamental assertions. Content includes a brief description of the theory of acoustic and electromagnetic fields to underline the similarities and differences as compared to elastodynamics. It also covers vector algebra and analysis elastic plane and Rayleigh surface waves and ultrasonic beams as well as transducer radiation inverse scattering and ultrasonic nondestructive imaging. Includes numerical computations to explain wave propagation phenomena and compare results of analytical formulations Although ultrasonic nondestructive testing can often be roughly understood in terms of plane waves and beams this book addresses the key issues of transducer radiation and defect scattering and imaging respectively. The authors physically formulate point source synthesis and in mathematical terms they use representation integrals with Green functions always including intuitive interpretations with mathematical evaluations. Replacing cumbersome index notation with a coordinate-free version this reference offers step-by-step documentation of relevant tensorial elastodynamic cases involving isotropic and anisotropic materials. It provides all necessary mathematical tools readers require to understand the mathematical and physical basis for ultrasonic nondestructive testing. | Ultrasonic Nondestructive Testing of Materials Theoretical Foundations

GBP 94.99
1