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Principles of Toxicology Testing

Principles of Toxicology Testing

Nationally toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently the second edition of Principles of Toxicology Testing starts with basic toxicological principles including absorption distribution metabolism and elimination of toxins including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies including dermal ocular and reproductive toxicity testing. In addition mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity target organ toxicity and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications the concepts of standardizatio

GBP 175.00
1

PAT: Portable Appliance Testing In-Service Inspection and Testing of Electrical Equipment

Viburnum Tinus 'Eve Price' (Laurustinus 'Eve Price') - Half Standard

Viburnum Tinus 'Eve Price' (Laurustinus 'Eve Price') - Half Standard

Viburnum can be deciduous or evergreen shrubs with opposite, simple or palmately lobed leaves and clusters of small, often fragrant white or pink flowers, followed by red, blue or black berries. 'Eve Price' is a bushy, medium-sized evergreen shrub with broadly oval, leathery dark green leaves and, from late winter, flattened clusters of deep pink buds opening to small, starry white flowers. Berries deep metallic-blue. Product Dimensions 10 litre pot: trunk 80 – 120 cm (2.6-3.9 ft), canopy spread app. 20 – 40 cm (0.6-1.3 ft) 15-18 litre pot: trunk 80 – 120 cm (2.6-3.9 ft), canopy spread app. 30 – 40 cm (1-1.3 ft) 25 litre pot: trunk 80 – 120 cm (2.6-3.9 ft), canopy spread app. 40 – 60 cm (1.3-2 ft) 35 litre pot: trunk 80 – 120 cm (2.6-3.9 ft), canopy spread app. 40 – 60 cm (1.3-2 ft) 50 litre pot: trunk 80 – 120 cm (2.6-3.9 ft), canopy spread app. 50 – 80 cm (1.6-2.6 ft) Latin Name: Viburnum Tinus 'Eve Price' English Name: Laurustinus 'Eve Price' Species: Adoxaceae Genus: Viburnum Foliage Type: Evergreen. Foliage: Green. Flower: White. Flowering Period: April-May. Suggested Location: Outdoor. Suggested Soil Type: Moderately fertile, humus-rich, well-drained soils. Suggested Exposure to Sunlight: Full Sunlight or Partial Shade or Full Shade. Suggested Exposure to Weather: Sheltered or Exposed. Hardiness Rating: Medium (H4). Lowest Temperature Tolerance: -10 °C to -5 °C (14 °F to 23 °F) Suggested Uses: Small gardens. Rock gardens. Groups. Borders. Maintenance: Dead or damaged growth may be cut back in May. Growth Habit: Bushy. Growth Speed: Slow. Delivery Cost: This is calculated based on the total size, weight and quantity of your order, as well as the location of your delivery address. You will see the final price at the Online Checkout Page (before making payment) – our website will automatically calculate the lowest possible delivery price and apply discounts to orders of certain products – giving you the best value delivery every time! Please note that high-volume orders will decrease your delivery costs significantly by spreading the price across multiple items. Visit our Delivery Policy page for more information.

GBP 93.95
1

Ever Simply Sleep Anti Allergy Microfibre Duvet - Single Size - Galvin and Galloway

Ever Simply Sleep Anti Allergy Microfibre Duvet - King Size - Galvin and Galloway